Nov 18, 2025; Atlanta, Georgia, USA; Detroit Pistons guard Cade Cunningham (2) does an interview after a victory over the Atlanta Hawks at State Farm Arena. Mandatory Credit: Brett Davis-Imagn Images
Brett Davis-Imagn Images

Detroit Pistons vs Milwaukee Bucks Prediction 11/22/2025 Today’s NBA Picks

Pick details

MATCHUP Detroit Pistons Milwaukee Bucks
Team Records 13-2 8-8
Spread -8.5 -115 +8.5 -105
Moneyline -380 +300
Total Over 223.5 (-108) Under 223.5 (-112)
Where Fiserv Forum, Milwaukee, WI
When Saturday, November 22, 2025
Time 08:00 PM EST
TV FanDuel SN DET

The Detroit Pistons and Milwaukee Bucks meet Saturday in NBA action at the Fiserv Forum. Here’s a Detroit Pistons vs Milwaukee Bucks Prediction. This article will include a Detroit Pistons vs Milwaukee Bucks Pick.

Detroit Pistons Betting Preview


The Detroit Pistons beat the Hawks and Pacers, and they play the Pacers next. The Pistons have won 11 straight games.

The Detroit Pistons are averaging 118.9 points on 48.1 percent shooting and allowing 112.1 points on 43.9 percent shooting. Cade Cunningham is averaging 27.3 points and 5.4 rebounds, while Jalen Duren is averaging 20.6 points and 1.8 assists. Tobias Harris is the third double-digit scorer and Ausar Thompson is grabbing 6.2 rebounds. The Detroit Pistons are shooting 34.6 percent from beyond the arc and 74.2 percent from the free-throw line. The Detroit Pistons are allowing 35.3 percent shooting from deep and are grabbing 46.9 rebounds per game.

Milwaukee Bucks Betting Preview


The Milwaukee Bucks lost to the 76ers and Cavs, and they play the Trail Blazers next. The Bucks have lost 4 of their last 5 games.

The Milwaukee Bucks are averaging 117.4 points on 49.5 percent shooting and allowing 119 points on 47 percent shooting. Giannis Antetokounmpo is averaging 31.2 points and 10.8 rebounds, while Ryan Rollins is averaging 18.3 points and 3.9 rebounds. Kyle Kuzma is the third double-digit scorer and Myles Turner is grabbing 6.5 rebounds. The Milwaukee Bucks are shooting 41.3 percent from beyond the arc and 70.3 percent from the free throw line. The Milwaukee Bucks are allowing 34.7 percent shooting from deep and are grabbing 39.8 rebounds per game.

Why the Milwaukee Bucks will win

  • The Bucks have won each of their last 11 night games against the Pistons.
  • The Pistons have lost 13 of their 14 previous night games at Fiserv Forum.
  • The Bucks have covered the spread in seven of their last eight night games against the Pistons following a home loss.
  • The Pistons have failed to cover the spread in each of their last four road games following a road win.

Why the Detroit Pistons will win

  • The Pistons have won each of their last 10 games following a win.
  • The Bucks have lost each of their last four games against teams that held a winning record.
  • The Bucks have failed to cover the spread in seven of their last eight games after coming off overtime.
  • The Pistons have covered the spread in each of their last four games against Eastern Conference opponents.

Total Points Facts

  • Each of the Bucks’ last seven night games against the Pistons following a home loss have gone UNDER the total points line.
  • Each of the Pistons’ last four games at Fiserv Forum have gone OVER the total points line.

Milwaukee Bucks Player Facts

  • Cole Anthony ranks 4th amongst qualified players for assists per 36 minutes (9.8) this season.
  • Ryan Rollins is one of only 15 qualified Guards in the league shooting at least 50% from the field this season.

Detroit Pistons Player Facts

  • Isaiah Stewart ranks T4th amongst qualified players for blocks per game (2.0) this season.
  • Ausar Thompson rank 11th amongst qualified players for steals + blocks per game (2.6) this season.

Matchup/League Facts

  • The Bucks rank 30th for second chance points (170) this season.
  • The Bucks rank 30th for second chance points per game (10.6) this season.
  • The Pistons rank 1st for points in the paint per game (59.3) this season.
  • Eleven different Pistons players have scored 15+ points in a game this season – equal-most in the league.

Detroit Pistons vs Milwaukee Bucks Injury Report


The Bucks will be without Kevin Porter Jr. and Taurean Prince. Giannis Antetokounmpo is out with a groin injury.

The Pistons will be without Marcus Sasser, Tobias Harris, Jaden Ivey, and Bobi Klintman.

Detroit Pistons vs Milwaukee Bucks Prediction


The Bucks have lost 3 straight games and are struggling to find offense without Antetokounmpo. The Pistons have not only won 11 straight games, but they’re 11-4 ATS on the season. The Pistons are tied with the Lakers with a cover percentage of 73.3 percent, which is the best in the NBA. At this point, you just blindly back the Pistons until the tickets stop cashing. I’m not stepping in front of the Pistons for the Bucks without their best player. I’ll lay the points with the Pistons.

Randy Chambers's Pick: Detroit Pistons -8.5

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