Oct 22, 2025; New York, New York, USA; New York Knicks guard Jalen Brunson (11) controls the ball against Cleveland Cavaliers guard Jaylon Tyson (20) during the first quarter at Madison Square Garden. Mandatory Credit: Brad Penner-Imagn Images
Brad Penner-Imagn Images

Boston Celtics vs New York Knicks Prediction 10/24/2025 Today’s NBA Picks

Pick details

Boston (0-1) vs New York (1-0)

October 24, 2025 at 07:30 PM EDT

The Line: Betting Odds: New York -5.5 — Over/Under: +228.5

(Get latest betting odds)

The Boston Celtics pay a visit to the New York Knicks at Madison Square Garden on Friday night. Here’s a Boston Celtics vs New York Knicks Prediction. This article will include a Boston Celtics vs New York Knicks Pick.

Boston Celtics Betting Preview 

The Boston Celtics will be eager to atone for their tough defeat on opening night after falling just short to the 76ers in a 117-116 on Wednesday. Derrick White drained four 3-pointers to lead the team with 25 points on seven of 20 shooting, Jaylen Brown added 25 points with six rebounds and four assists, Neemias Queta scored 17 points while Payton Pritchard chipped in with 16 points.

As a team, the Celtics shot 45 percent from the field and 11 of 43 from the 3-point line as they dominated the third quarter by 35-18 to take a 13-point lead after trailing for most of the first half. However, they allowed the 76ers to hang around, and it cost them in the fourth quarter when they leaked 42 points to come up just short in the end. In fact, the Celtics held the lead late in the contest, before they went ice-cold and managed just four points during a 3:30 stretch to allow the 76ers to run them down and steal the lead.

New York Knicks Betting Preview 

Meanwhile, the New York Knicks will be gunning for a second straight victory to kick off their season after outlasting the Cavaliers in a 119-111 home win on Wednesday. OG Anunoby led the team with 24 points, 14 rebounds and three steals on nine of 17 shooting, Jalen Brunson added 23 points with five assists, Karl-Anthony Towns added 19 points iwth 11 rebounds while Mikal Bridges chipped in with 16 points and six assists.

As a team, the Knicks shot just 43 percent from the field and 14 of 40 from the 3-point line as they looked to be in trouble when they allowed the Cavaliers to erase their early 15-point halftime lead. But they didn’t panic and instead went on a crucial 14-4 run in the fourth quarter to reclaim the lead and grind out a gritty win at home. 

Why the New York Knicks will win

  • The Knicks have won each of their last 17 night games against Atlantic Division opponents that held a losing record.
  • The Celtics have lost five of their last six road openers against Atlantic Division opponents.
  • The Knicks have covered the spread in each of their last six home games against teams that held a losing record.
  • The Celtics have failed to cover the spread in seven of their last eight night games against Eastern Conference opponents that held a winning record.

Why the Boston Celtics will win

  • The Celtics have won each of their last 13 road games after losing as favorites.
  • The Knicks have lost each of their last six night games following a home win.
  • The Celtics have covered the spread in each of their last 13 road games after losing as favorites.
  • The Knicks have failed to cover the spread in seven of their last eight home games after winning as underdogs.

Total Points Facts

  • Each of the Celtics’ last seven games as road underdogs have gone UNDER the total points line.
  • Five of the Knicks’ last six games as home favorites have gone UNDER the total points line.

Boston Celtics vs New York Knicks Prediction

The Celtics are still shorthanded with Jayson Tatum and Luka Garzo both ruled out again, while the Knicks have ruled out Mitchell Robinson. They are keeping eyes on Josh Hart and Karl-Anthony Towns, who are both questionable for this matchup. The line could shift a little depending on the availability of Hart and Towns, but the Celtics shipped away plenty of depth in the offseason. They look thin on offensive firepower without Tatum in the lineup, so I am banking on the Knicks to take advantage and come away with a win and cover at home in this spot.

Peter Tran's Pick: New York -5.5

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