Oct 24, 2025; Houston, Texas, USA; Detroit Pistons forward Paul Reed (7) drives with the ball as Houston Rockets guard Reed Sheppard (15) defends during the fourth quarter at Toyota Center. Mandatory Credit: Troy Taormina-Imagn Images
Troy Taormina-Imagn Images

Boston Celtics vs Detroit Pistons Prediction 10/26/2025 Today’s NBA Picks

Pick details

Boston (0-2) vs Detroit (1-1)

October 26, 2025 at 03:30 PM EDT

The Line: Betting Odds: Detroit -3.5 — Over/Under: +227.5

(Get latest betting odds)

The Boston Celtics travel to Little Caesars Arena to do battle with the Detroit Pistons on Sunday. Here’s a Boston Celtics vs Detroit Pistons Prediction. This article will include a Boston Celtics vs Detroit Pistons Pick.

Boston Celtics Betting Preview 

The Boston Celtics are still searching for their first victory of the season and are coming into this game fresh off a 105-95 road defeat to the Knicks on Friday. Jaylen Brown led the team with 23 points, four rebounds and three assists on nine of 18 shooting, Sam Hauser drained six 3-pointers to finish with 18 points while Derrick White chipped in with 15 points, four rebounds and four assists.

As a team, the Celtics shot just 42 percent from the field and 15 of 44 from the 3-point line as they got off to a solid start and looked to be in the contest. However, they got dominated by 42-14 in a nightmare of a second quarter to have them trailing by 24 points early. The Celtics put up a stiffer challenge in the second half, but they were never truly a threat as they could never cut the deficit to single digits. Payton Pritchard had a night to forget as he shot just two of 10 from the field and one of seven from the 3-point line to finish with eight points. 

Detroit Pistons Betting Preview 

Meanwhile, the Detroit Pistons have split their first two games of the season and they will be eager to build some momentum after sneaking past the Rockets in a 115-111 road win on Friday. Cade Cunningham led the team with 21 points, seven rebounds and nine assists, Ausar Thompson added 19 points while Duncan Robinson chipped in with 17 points. A

s a team, the Pistons shot 46 percent from the field and 16 of 39 from the 3-point line as they battled the Rockets in a tight contest that remained with single digits. Until the Pistons’ defense kept the Rockets to just one point in the final 2:18 to allow Cunningham to seal the victory with free throws in the final seconds. 

Why the Detroit Pistons will win

  • The Pistons have won nine of their last 10 games against Eastern Conference opponents that held a losing record.
  • The Celtics have lost four of their last five games against Eastern Conference opponents.
  • The Pistons have covered the spread in each of their last five games against Atlantic Division opponents that held a losing record.
  • The Celtics have failed to cover the spread in six of their last seven games as road underdogs against Eastern Conference opponents.

Why the Boston Celtics will win

  • The Celtics have won each of their last 10 day games against Eastern Conference opponents.
  • The Pistons have lost each of their last five games as favorites.
  • The Celtics have covered the spread in each of their last eight road games against Central Division opponents following a loss.
  • The Pistons have failed to cover the spread in 10 of their last 11 games as home favorites after winning as underdogs.
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Total Points Facts

  • Each of the Celtics’ last eight games as road underdogs have gone UNDER the total points line.
  • Four of the Pistons’ last five home games against opponents who are on the first leg of a back-to-back have gone UNDER the total points line.

Detroit Pistons Player Facts

  • Duncan Robinson is one of only six qualified players in the league averaging at least 1.5 threes and 1.5 blocks this season.
  • Jalen Duren ranks 9th amongst qualified players for blocks per 36 minutes (3.4) this season.

Boston Celtics Player Facts

  • Anfernee Simons ranks T12th amongst qualified players for steals per game (2.0) this season.
  • Payton Pritchard ranks T16th in the Eastern Conference amongst qualified players for steals per game (1.5) this season.

Matchup/League Facts

  • The Pistons rank T1st in the league for Q2 win percentage this season (100.0%).
  • The Pistons rank T1st in the league for Q4 win percentage this season (100.0%).
  • The Celtics rank 1st in the league for opponent steals per game this season (5.0).
  • The Celtics have suffered the largest comeback loss when leading through Q3 this season – led by 11 points @ 76ers on October 22.

Boston Celtics vs Detroit Pistons Prediction

The Celtics are still missing Jayson Tatum, and they are keeping eyes on Jaylen Brown and Luka Garza who are both currently listed as questionable. The Pistons have listed both Caris LeVert and Marcus Sasser as doubtful for this contest. These teams met four times last season with the Celtics winning three of those meetings, but they could be seriously shorthanded for this one which opens the door for the Pistons to get some revenge. I get why the line is so short for this matchup, but I think the Pistons get the job done at home in this spot.

Peter Tran's Pick: Detroit -3.5

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