San Antonio Spurs vs Detroit Pistons Prediction 3/25/25 NBA Picks

The San Antonio Spurs have sprung to life with five wins from their past seven games overall and they will be gunning for a fourth straight victory after blowing past the Raptors in a 123-89 road win on Sunday. Devin Vassell led the team with 25 points, six rebounds and three assists on 11 of 14 shooting, Julian Champagnie added 20 points off the bench while Stephon Castle chipped in with 15 points. As a team, the Spurs shot 47 percent from the field and 14 of 43 from the 3-point line as they dominated from the start and outscored the Raptors by 36-16 in the first quarter. Before they poured in another 35 points in the third quarter to push the lead out to 38 points. The Spurs will face the Cavaliers following this one.

Meanwhile, the Detroit Pistons have been in decent form as they've won five of their last eight games overall and they will be looking to stay hot after outlasting the pesky Pelicans in a 136-130 home win on Sunday. Ronald Holland led the team with 26 points and six assists on 10 of 14 shooting off the bench, Jalen Duren added 22 points with 12 rebounds on eight of 11 shooting while Marcus Sasser chipped in with 20 points on six of nine shooting. As a team, the Pistons shot 54 percent from the field and 13 of 27 from the 3-point line as they wasted an early 13-point lead. They found themselves in a real battle with the Pelicans until the fourth quarter, where the Pistons poured in 43 points to escape with the narrow win at home. The Pistons will take on the Cavs, Timberwolves, and Thunder after this game.

Why the Detroit Pistons will win

• The Spurs have lost each of their last nine games as underdogs following a win.
• The Pistons have won 13 of their last 15 games against teams that held a losing record.
• The Spurs have failed to cover the spread in seven of their last eight games as road underdogs.
• The favorites have covered the spread in each of the last five games between the Spurs and Pistons.

Why the San Antonio Spurs will win

• The Pistons have lost 16 of their last 17 games against Southwest Division opponents following a win.
• The Spurs have won each of their last five night games against the Pistons following a road win.
• The Pistons have failed to cover the spread in each of their last 10 games at Little Caesars Arena against Western Conference opponents that held a losing record.
• The Spurs have covered the spread in each of their last five night games against the Pistons following a road win.

The Spurs are still missing De'Aaron Fox and Charles Bassey with Stephon Castle listed as questionable, while the Pistons are keeping an eye on Cade Cunningham and Tim Hardaway Jr who are both questionable. This is one of those games where you should check the lineups before tip-off. These teams last met on Feb. 21, and it was the Pistons who romped to a 125-110 road win. The Spurs have been pretty good over the last week or so, but the Pistons are clear favorites in this spot, and I think they get the job done with another double-digit win to sweep the season series.