Cleveland Cavaliers vs Portland Trail Blazers Prediction 3/25/25 NBA Picks

Portland Trail Blazers (32-40) vs Cleveland Cavaliers (57-14)

Game Info: Tuesday, March 25, 2025 at 10:00 pm (Moda Center)

Betting Odds: Portland Trail Blazers +6.5 -- Over/Under: 231 Click Here for the Latest Odds

Where to Watch: BlazerVision

The Cleveland Cavaliers and Portland Trail Blazers meet Tuesday in NBA action at the Moda Center. Here’s a Cleveland Cavaliers vs Portland Trail Blazers Prediction. This article will include a Cleveland Cavaliers vs Portland Trail Blazers Pick.

Cleveland Cavaliers Betting Preview 

The Cleveland Cavaliers lost to the Suns, beat the Jazz, and they play the Spurs, Pistons, and Clippers next. The Cavs have lost four of their last five games and are two games behind the Thunder for the best record in the NBA.

The Cleveland Cavaliers are averaging 122.3 points on 49.2 percent shooting and allowing 111.9 points on 45.5 percent shooting. Donovan Mitchell is averaging 23.7 points and 4.8 assists, while Darius Garland is averaging 20.7 points and 6.6 assists. Evan Mobley is the third double-digit scorer and Jarrett Allen is grabbing 10 rebounds. The Cleveland Cavaliers are shooting 38.4 percent from beyond the arc and 78.7 percent from the free throw line. The Cleveland Cavaliers are allowing 36.1 percent shooting from deep and are grabbing 45.1 rebounds per game.

Portland Trail Blazers Betting Preview 

The Portland Trail Blazers beat the Nuggets, lost to the Celtics, and they play the Kings, Knicks, and Hawks next. The Trail Blazers have won four of their last five games and are three games out of a play-in spot. 

The Portland Trail Blazers are averaging 111 points on 45.2 percent shooting and allowing 114.1 points on 47 percent shooting. Anfernee Simons is averaging 19.5 points and 2.7 rebounds, while Shaedon Sharpe is averaging 17.6 points and 4.2 rebounds. Deni Avdija is the third double-digit scorer and Deandre Ayton is grabbing 10.2 rebounds. The Portland Trail Blazers are shooting 34.8 percent from beyond the arc and 76.8 percent from the free-throw line. The Portland Trail Blazers are allowing 36.3 percent shooting from deep and are grabbing 44.4 rebounds per game.

Why the Portland Trail Blazers will win

  • The Cavaliers have lost each of their last six games at Moda Center following a road win.
  • The Trail Blazers have won four of their last five games as home underdogs against Central Division opponents.
  • The Cavaliers have failed to cover the spread in each of their last six games at Moda Center following a road win.
  • The Trail Blazers have covered the spread in nine of their last 10 games as underdogs against Central Division opponents.

Why the Cleveland Cavaliers will win

  • The Cavaliers have won each of their last nine night games following a road win.
  • The Trail Blazers have lost each of their last seven games as underdogs following a loss.
  • The favorites have covered the spread in each of the last six games between the Cavaliers and Trail Blazers at Moda Center.
  • The Trail Blazers have failed to cover the spread in three of their last four games against Eastern Conference opponents that held a winning record.

Matchup/League Facts

  • The Trail Blazers rank 29th in the league for Q1 points per game this season (26.2).
  • The Trail Blazers rank 29th in the league for Q1 win percentage this season (30.6%).
  • The Cavaliers rank 1st in the league for Q4 points per game this season (29.7).
  • The Cavaliers rank 1st in the league for H1 points per game this season (61.5).

Cleveland Cavaliers vs Portland Trail Blazers Injury Report 

The Trail Blazers won’t have Deandre Ayton, Robert Williams III, and Jerami Grant. Dalano Banton is questionable with an illness.

The Cavs will be without Jaylon Tyson and Donovan Mitchell.

Cleveland Cavaliers vs Portland Trail Blazers Prediction

The Cavaliers are getting the benefit of the doubt because of what they’ve done this season both SU and ATS, but this line is a bit off when you consider what they’ve done over the last week and the fact there’s no Mitchell. The Trail Blazers keep playing hard, winning games, and they’re a profitable 41-30-1 ATS on the season. The Trail Blazers are also just three games out of a play-in spot, so there’s motivation to keep trying to win games. The Cavs are 3-7 ATS in their last 10 games. The Trail Blazers took the Cavs to overtime on the road earlier this month. Give me the Trail Blazers and the points.

Randy’s Pick Portland Trail Blazers +6.5

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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