Washington Nationals vs Miami Marlins Prediction 9/10/2025 Today’s MLB Picks

In this article, we will formulate a Nationals vs Marlins Prediction for this MLB game on Wednesday, September 10th at the loanDepot park in the third game of this series, with the Nationals having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 66-79 record this season and are sitting on the third place of the NL East. The Marlins have a 32-41 home record and are 72-68 in over/under. They are coming off a 5-7 home defeat by the Nationals, and are 1-7 in their last 8 games. Over is 4-1-1 in their last 6 games and are playing the Tigers and the Rockies next.

The Marlins have a .250 batting average this season, .314 OBP and .393 slugging percentage. Miami’s pitching staff has a 4.80 ERA and 1.33 WHIP.  Xavier Edwards leads the Marlins with 144 hits, while Kyle Stowers is the team’s best hitter with a .288 batting average. He also adds team-highs in RBI with 73, and in home runs with 25.

Eury Perez (R) is the projected starting pitcher for the Marlins, and he has a 6-5 record, 4.66 ERA and 1.10 WHIP.

Washington Nationals Preview

The Washington Nationals have a 60-84 record this season and are sitting on the last place of the NL East. The Nationals have a 31-42 road record and are 73-62 in over/under. They are coming off 7-5 road victory over the Marlins, and are 7-1 in their last 8 games. Over is 5-1 in their last 6 games and are playing the Pirates and the Braves next.

The Nationals have a .245 batting average this season, .309 OBP and .392 Slugging percentage. Washington’s pitching staff has a 5.29 ERA and 1.43 WHIP. James Wood leads the Nationals with 140 hits, while CJ Abrams is the team’s best hitter with a .268 batting average. James Wood adds a team-high 88 RBI and leads the team in home runs, with 27.

Jake Irvin (R) is the projected starting pitcher for the Nationals, and he has an 8-11 record, 5.71 ERA and 1.44 WHIP.

Washington Nationals @ Miami Marlins Betting Trends: September 10, 2025

• Probable Starting Pitcher: Eury Perez      Record this season: 6-5      ERA: 4.66
• Home Record: 3-2
• Last 5 against Nationals: 1-1

Why the Miami Marlins will win

• The Marlins have covered the run line in four of their last five night games against NL East opponents following a home loss.
• The Nationals have trailed after 5 innings in 14 of their last 18 games as road underdogs against NL East opponents.

• Probable Starting Pitcher: Jake Irvin      Record this season: 8-11      ERA: 5.71
• Road Record: 6-7
• Last 5 against Marlins: 1-0

Why the Washington Nationals will win

• The Marlins have lost eight of their last nine games as home favorites against NL East opponents.
• The Nationals have won seven of their last eight games as road underdogs against the Marlins.
• The Marlins have failed to cover the run line in each of their last 16 games as home favorites against NL East opponents.
• The Nationals have covered the run line in each of their last 11 games as road underdogs against the Marlins.
• The Marlins have trailed after 3 innings in five of their last six games against opponents that held a losing record.
• The Marlins have trailed after 5 innings in each of their last seven games against opponents that held a losing record.

Total Runs Facts

• Eight of the Marlins’ last nine games as favorites against the Nationals have gone OVER the total runs line.
• Each of the Nationals’ last five games as underdogs against the Marlins have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Nationals’ last eight games at LoanDepot Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Marlins’ last seven home games.

Miami Marlins Player Prop Facts

• Joey Wiemer has hit a home run in each of his last two appearances against the Nationals.
• Kyle Stowers has recorded a Double in each of his last three home appearances against the Nationals.
• Kyle Stowers has recorded two or more hits in each of his last three home appearances against the Nationals.

Washington Nationals Player Prop Facts

• Josh Bell has hit at least one home run in each of the Nationals’ last three games.
• CJ Abrams has recorded at least one Double in each of the Nationals’ last four night games.
• Josh Bell has recorded at least one hit in each of the Nationals’ last nine road games against NL opponents that held a losing record.

Matchup/League Facts

• The Marlins rank T4th in the league for triples this season (26).
• The Marlins rank T26th in the league for home runs this season (138).
• The Nationals rank 29th in the league for ERA this season (5.29).
• The Nationals rank 29th in the league for opponent batting average this season (.266).

Nationals vs Marlins Prediction

The Nationals have won their last five head-to-head meetings against the Marlins, and are 3-2 wins in their last 5 meetings in Miami. Over is 3-0 in their last 3 meetings.

In this Nationals vs Marlins Prediction, the Marlins are coming as -160 home favorites. This one is simple. Both pitchers struggle with a combined 10.37 ERA this season. Irvin has been even weaker on the road for the Nats, with a 6.19 road ERA. Both pitchers are coming into this matchup in horrendous form, as they have an 8.55 and 10.80 ERA across their last five starts respectively. The first two games in this series had 22 and 12 total runs, so expect another high-scoring affair. Take the over 8.5 runs in this one.