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Twins vs Astros Prediction 6/15/25 MLB Picks

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Houston Astros (40-30) vs Minnesota Twins (36-34)

June 15, 2025 at 02:10 PM EDT

The Line: Betting Odds: Houston Astros -137 / Minnesota Twins +112 — Over/Under: 8.5

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In this article, we will formulate a Twins vs Astros prediction for this MLB game on Sunday, June 15th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Minnesota Twins Betting Preview

The Minnesota Twins are 36-34 this year after they lost the first two games in this series by scores of 3-10 and 2-3. In their game two loss, Minnesota tied the game at two in the fifth inning, but couldn’t find any more offense in the game for the loss. The Twins recorded three hits in the game, and they were led by Lee, who went 1-4 with one home run and two RBIs in the loss. Minnesota started Ryan, who allowed two hits and two earned runs over 7.0 innings, while Duran was charged with the loss. 

Prior to this series, the Twins lost two out of three against the Rangers and two out of three against the Blue Jays. Minnesota has lost seven of its last nine games, and they are currently tied for second in the AL Central standings. The Minnesota pitching staff has a 3.90 ERA with a 1.22 WHIP and a .241 opponent batting average, while their offense has scored 294 runs with a .242 batting average and a .313 on-base percentage this season. Byron Buxton has led Minnesota with 11 home runs and 41 RBIs, while Trevor Larnach has added 10 home runs and 32 RBIs this year. The projected starting pitcher for Minnesota is Simeon Woods Richardson, who is 2-3 with a 5.74 ERA and a 1.61 WHIP over 42.1 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 40-30 this season after they won game two by a score of 3-2 on Saturday. Houston led 2-0 in the third inning, but didn’t score again until the bottom of the ninth for the walk-off win. The Astros recorded four hits in the game, and they were led by Diaz, who went 1-4 with one home run and two RBIs in the win. Houston started Brown, who allowed three hits and two earned runs over 7.0 innings, while Hader picked up the win. 

Prior to this series, the Astros won two out of three against the White Sox and two out of three against the Guardians. Houston has won seven of their last nine games, and they are currently first in the AL West standings. The Houston pitching staff has a 3.47 ERA with a 1.15 WHIP and a .218 opponent batting average, while their offense has scored 290 runs with a .255 batting average and a .319 on-base percentage this season. Isaac Paredes has led Houston with 15 home runs and 42 RBIs, while Jeremy Pena has added nine home runs and 34 RBIs this year. The projected starting pitcher for Houston is Brandon Walter, who is 0-0 with a 1.64 ERA and a 0.91 WHIP over 11.0 innings pitched this season. 

Why the Astros will beat the Twins 

  • The Twins have lost eight of their last nine day games after playing the previous day.
  • The Astros have won each of their last five home games after playing the previous day.
  • The Twins have failed to cover the run line in five of their last six games against AL West opponents.
  • The Astros have covered the run line in four of their last five games against teams that held a winning record.
  • The Twins have trailed after 5 innings in three of their last four games at Daikin Park.
  • The Astros have led after 3 innings in each of their last four games against American League opponents.

Total Runs Facts

  • Four of the Twins’ last five day games against American League opponents have gone OVER the total runs line.
  • Each of the Astros’ last three games as favorites against the Twins have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last four day games against AL Central opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Twins’ last six games as road underdogs.

Houston Astros Player Prop Facts

  • Yainer Diaz has recorded a Double in three of the Astros’ last four games against AL Central opponents at Daikin Park.
  • Jeremy Pena has recorded at least one hit in each of the Astros’ last 13 games as favorites.
  • Isaac Paredes has recorded at least one RBI in each of the Astros’ last five games as home favorites against AL Central opponents.
  • Jeremy Pena has scored at least one run in each of the Astros’ last seven games at Daikin Park.
  • Isaac Paredes has hit a home run in each of his last two home appearances against AL Central opponents that held a winning record.

Minnesota Twins Player Prop Facts

  • Carlos Correa has recorded at least one Double in three of his last four appearances with the Twins as underdogs against the Astros.
  • Carlos Correa has recorded at least one RBI in seven of his last eight appearances with the Twins as underdogs against AL West opponents.
  • Ty France has recorded two or more hits in each of his last five appearances with his team as an underdog against AL West opponents.
  • Byron Buxton has scored at least one run in each of his last five appearances with the Twins as underdogs against AL opponents.
  • Trevor Larnach has hit a home run in each of his last two appearances with the Twins as road underdogs against the Astros.

Twins vs Astros Prediction 

Houston comes into this matchup riding a four-game winning streak, and they are looking for the series sweep here. The Astros are 26-13 at home this season, while the Twins are 16-22 on the road. Minnesota has lost three games in a row, and they have allowed 29 runs in that span. The Twins are starting Woods Richardson, who has allowed 12 earned runs in his last two starts. Houston is going with Walter, who has allowed two earned runs in 11.0 innings this year. I don’t trust Woods Richardson or the Twins on the road, so give me Houston here. 

David Racey's Pick: Astros ML

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