Sep 15, 2025; Tampa, Florida, USA; Toronto Blue Jays outfielder George Springer (21) hits an rbi single against the Tampa Bay Rays in the eleventh inning at George M. Steinbrenner Field. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

Toronto Blue Jays vs Tampa Bay Rays Prediction 9/16/2025 Today’s MLB Picks

Pick details

Toronto (88-62) vs Tampa Bay (73-76)

September 16, 2025 at 07:35 PM EDT

The Line: Betting Odds: Tampa Bay +1.5 — Over/Under: +8.5

(Get latest betting odds)

The Toronto Blue Jays vs Tampa Bay Rays meet on Tuesday in MLB action from the George M. Steinbrenner Field. Here’s a Toronto Blue Jays vs Tampa Bay Rays prediction. We will look at this from a betting perspective and determine the best Blue Jays vs Rays pick. We will examine:

The Toronto Blue Jays’ recent form and player performance

The Tampa Bay Rays’ recent form and player performance

Recent betting trends and streaks involving the Rays

Recent betting trends and streaks involving the Blue Jays

Recent betting trends in games played between the Rays and Blue Jays

A summary that ties it all together and produces a favorable betting outcome for the Blue Jays and Rays game.

Blue Jays Pulled it Out


The Blue Jays didn’t play their best game on Monday, at least in terms of the offense, but the pitching was dominant, and they were able to win 2-1 in extra innings. Trey Yesavage went five innings giving up three hits and one run. He had nine strikeouts and two walks. George Springer finished with a hit and a run driven in.

The Blue Jays are averaging 5.03 runs while their pitching is giving up 4.45 runs per game. The offense is ranked 4th while the pitching is ranked 19th. George Springer has hit 29 home runs and driven in 75 RBIs so far this season. Getting the start for the Blue Jays will be Jose Berrios who sits with a 9-5 record and an ERA of 3.99. Against the Houston Astros in his last 5.1 innings giving up five hits and two runs. Two starts ago against the Cincinnati Reds, he went two innings giving up five hits and six runs. 

Rays Have Blown It

The Rays have really blown it as of late, and they are out of the playoff race because of it. On Monday they had their chances to come away with a victory, but they couldn’t get the big hits, and they suffered another loss. Yandy Diaz was the top player, and he finished with three hits, two walks, and one RBI.  At this point, they should get the young guys some playing time, because there isn’t much left to play for. 

The Rays are averaging 4.48 runs while their pitching is giving up 4.15 runs per game. The offense is ranked 13th while the pitching is ranked 10th. Junior Caminero is having a huge season and has hit 44 home runs and driven 108 RBIs so far. Getting the start for the Rays will be Ryan Pepiot who sits with an 11-10 record and an ERA of 3.59. Against the Guardians in his last start he went five innings giving up zero hits and zero runs. Over his last three starts, he has given up zero runs in 15 innings. 

Toronto Blue Jays vs Tampa Bay Rays Prediction


The Blue Jays offense has been strong this season, but their bats are going to be ice cold, at least to start this game. Pepiot is on the mound for the Rays and he has been dominant heading into this start. Over his last three starts he has given up zero runs total, and he’s going to be dominant here. He might give up one run here, but it won’t be more than that. I don’t really have interest in trusting the Rays bullpen, but by betting it this way we  will take the bullpen out of the picture. Back the Rays on the money line in the first five innings.

Shane Mickle's Pick: Rays ML – First Five Innings

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