Toronto Blue Jays vs St. Louis Cardinals Prediction 6/11/25 MLB Picks

The Toronto Blue Jays and St. Louis Cardinals meet Wednesday in MLB action at Busch Stadium. Here’s a Toronto Blue Jays vs St. Louis Cardinals Prediction. This article will include a Toronto Blue Jays vs St. Louis Cardinals Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 37-30 on the year and play the Phillies, Diamondbacks, and White Sox next. The Toronto Blue Jays are batting .256 on the season, have a .325 OBP, and a .402 slugging percentage. The Toronto Blue Jays’ pitching staff has a 4.09 ERA and a 1.22 WHIP. Bo Bichette leads the Toronto Blue Jays with 78 hits and 38 RBI, while Vladimir Guerrero Jr. and Alejandro Kirk have combined for 131 hits and 60 RBI. 

Eric Lauer gets the ball for the Toronto Blue Jays, and he is 2-1 with a 2.08 ERA and 24 strikeouts this season. Lauer is 2-4 with a 7.27 ERA and 22 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 36-31 on the year and play the Brewers, White Sox, and Reds next. The St. Louis Cardinals are batting .258 on the season, have a .328 OBP, and a .396 slugging percentage. The St. Louis Cardinals’ pitching staff has a 3.96 ERA and a 1.28 WHIP. Brendan Donovan leads the St. Louis Cardinals with 77 hits and 26 RBI, while Willson Contreras and Lars Nootbaar have combined for 120 hits and 70 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 3-5 with a 3.82 ERA and 58 strikeouts this season. This will be Liberatore’s second career game against the Toronto Blue Jays.

Why the St. Louis Cardinals will win

• The Cardinals have won nine of their last 10 day games at Busch Stadium following a home loss.
• The Blue Jays have lost five of their last six day games against National League opponents following a road win.
• The Cardinals have covered the run line in 10 of their last 11 day games against AL East opponents that held a winning record.

Why the Toronto Blue Jays will win

• The Blue Jays have won nine of their last 10 games against National League opponents.
• The Cardinals have lost six of their last seven home games against American League opponents.
• The Blue Jays have covered the run line in 14 of their last 15 road games against National League opponents after playing the previous day.
• The Cardinals have failed to cover the run line in each of their last six home games against American League opponents.
• The Blue Jays have won the first inning in each of their last three road games against NL Central opponents that held a winning record.
• The Cardinals have trailed after 3 innings in five of their last six games against AL East opponents that held a winning record.
• The Blue Jays have led after 5 innings in six of their last seven road games against NL Central opponents that held a winning record.

St. Louis Cardinals Player Prop Facts

• Willson Contreras has recorded at least one RBI in each of the Cardinals’ last six home games against AL opponents.
• Masyn Winn has scored at least one run in each of the Cardinals’ last six games against AL East opponents at Busch Stadium.
• Willson Contreras has recorded at least one hit in each of the Cardinals’ last nine home games against AL opponents that held a winning record.
• Nolan Gorman has hit at least one home run in each of his last two home appearances against the Blue Jays after playing the previous day.
• Nolan Arenado has recorded at least one Single in nine of the Cardinals’ last 10 games against AL East opponents that held a winning record.
• Masyn Winn has recorded a Double in six of the Cardinals’ last eight home games against AL East opponents that held a winning record.

Toronto Blue Jays Player Prop Facts

• George Springer has recorded at least one RBI in each of his last six appearances at Busch Stadium against NL opponents that held a winning record.
• Vladimir Guerrero Jr. has scored at least one run in each of the Blue Jays’ last seven Wednesday games against opponents that held a winning record.
• Eric Lauer has recorded four or more strikeouts in 13 of his last 15 road appearances against NL Central opponents.
• Daulton Varsho has recorded at least one hit in 14 of his last 15 appearances against NL Central opponents.
• Alejandro Kirk has hit a home run in each of the Blue Jays’ last two games against the Cardinals.
• Alejandro Kirk has recorded at least one Single in each of his last seven appearances in day games.
• Bo Bichette ranks 8th in the league in Hits (78) this season.

Toronto Blue Jays vs St. Louis Cardinals Prediction

I’m not a fan of bullpen games, but Lauer hasn’t allowed a run in his last 9.2 innings, and he’s going deeper into games lately. Liberatore has allowed 15 hits and 11 earned runs in his last nine innings and has allowed four homers in his last 16 innings. The Blue Jays have quietly been one of the hottest teams in baseball over the last few weeks, while the Cardinals have had issues finishing games lately. I’ve been on the Blue Jays bandwagon a lot recently, and there’s no reason to jump off now. Give me the Blue Jays on Wednesday afternoon.

Randy Chambers's Pick: Toronto Blue Jays