Toronto Blue Jays vs St. Louis Cardinals Prediction 6/10/25 MLB Picks

In this article, we will formulate a Blue Jays vs Cardinals prediction for this MLB game on Tuesday, June 10, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays (36-30, 14-17 Away) are playing their best baseball of the season after winning ten of the previous 12 games. The Blue Jays swept the Athletics, beat the Phillies and Twins, and opened the current series in St. Louis with a 5-4 victory in extra innings. Alejandro Kirk led the offense with two RBI, while Jose Berrios pitched for 6.2 innings in a no-decision, allowing no runs on four hits with one strikeout and two walks. Yariel Rodriguez was credited with the win. 

This season, the Blue Jays average 4.26 runs per game (16th in the MLB) on a .253/.324/.399 triple-slash. When it comes to pitching, the Blue Jays’ staff has a 4.01 ERA (20th) and 1.21 WHIP (12th). Bo Bichette leads the Blue Jays with a .268 batting average, eight home runs, and 38 RBI this season.

Chris Bassitt will take the mound for the Blue Jays on Tuesday. The 36-year-old right-hander has a 6-3 record in 13 starts this year with a 3.56 ERA and 1.32 WHIP in 73.1 innings.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals (36-30, 22-12 Home) bounced back from losses to the Texas Rangers and Kansas City Royals with a series win over the Los Angeles Dodgers. The Cards had a chance to sweep the Dodgersbut lost Game 3, and then lost the opening game of the current series against the Blue Jays. St. Louis scored four runs in the 8th inning to get a 4-3 lead, but Toronto tied in the 9th and then won in extra innings. Ivan Herrera led the offense with three RBI, while Andre Pallante pitched for 6.0 innings in a no-decision, allowing two runs on seven hits with three strikeouts and one walk. Phil Maton took the loss. 

This year, the Cardinals average 4.62 runs per game (8th in the MLB) on a .257/.327/.393 triple-slash. When it comes to pitching, the Cardinals’ staff has a 3.87 ERA (16th) and 1.27 WHIP (16th). Willson Contreras leads the Cardinals with a .252 batting average, seven home runs, and 39 RBI this season.

The projected starting pitcher for the Cardinals is Miles Mikolas, who is 4-2 in 12 starts this season, with a 3.96 ERA and 1.27 WHIP in 61.1 innings.

Total Runs Facts

• Nine of the Cardinals’ last 10 night games against American League opponents have gone OVER the total runs line.
• Nine of the Blue Jays’ last 10 games after playing the previous day have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Cardinals’ last eight night games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Blue Jays’ last five games at Busch Stadium.

Matchup/League Facts

• The Cardinals rank 3rd in the league for home runs allowed this season (53).
• The Cardinals rank 4th in the league for doubles this season (120).
• The Blue Jays rank T28th in the league for home runs allowed this season (91).
• The Blue Jays rank T5th in the league for doubles this season (117).

Blue Jays vs Cardinals Prediction

The Blue Jays won seven of the previous ten H2H encounters, including the last four. Six of the last ten H2Hs went Over, which was the case in nine of Toronto’s previous ten, and in seven of St. Louis’ last ten games. Chris Bassitt had a rough May, during which he posted a 5.06 ERA, and he surrendered 11 runs in his last three starts. Bassitt allowed a .444 BA in 27 at-bats against the Cardinals in his career. Miles Mikolas, on the other hand, did have a better last month, registering a 3.08 ERA, but he did allow seven runs in his previous two starts. I think each pitcher will surrender 3+ in the opening six innings on Tuesday. Go with Over. 

Oliver Zivic's Pick: Over 8.5