Texas Rangers vs Cleveland Guardians Prediction 9/26/2025 Today’s MLB Picks

The Texas Rangers and Cleveland Guardians meet Friday in MLB action at Progressive Field. Here’s a Texas Rangers vs Cleveland Guardians Prediction. This article will include a Texas Rangers vs Cleveland Guardians Pick.

Texas Rangers Betting Preview

The Texas Rangers are 80-79 on the year after playing the Twins. The Texas Rangers are batting .34 on the season, have a .303 OBP, and a .382 slugging percentage. The Texas Rangers pitching staff has a 3.45 ERA and a 1.18 WHIP. Josh Smith leads the Texas Rangers with 124 hits and 35 RBI, while Wyatt Langford and Josh Jung have combined for 235 hits and 122 RBI.

Jack Leiter gets the ball for the Texas Rangers, and he is 9-10 with a 3.92 ERA and 138 strikeouts this season. Leiter is 1-1 with a 6.23 ERA and 11 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 86-73 on the year after playing the Tigers. The Cleveland Guardians are batting .226 on the season, have a .296 OBP, and a .373 slugging percentage. The Cleveland Guardians pitching staff has a 3.68 ERA and a 1.27 WHIP. Steven Kwan leads the Cleveland Guardians with 169 hits and 56 RBI while Jose Ramirez and Kyle Manzardo have combined for 272 hits and 153 RBI.

Slade Cecconi gets the ball for the Cleveland Guardians, and he is 7-6 with a 4.15 ERA and 106 strikeouts this season. Cecconi is 0-0 with a 3.09 ERA and 5 strikeouts in his career against the Texas Rangers.

Texas Rangers @ Cleveland Guardians Betting Trends: September 26, 2025

• Probable Starting Pitcher: Slade Cecconi      Record this season: 7-6      ERA: 4.15
• Home Record: 2-3
• Last 5 against Rangers: 0-0

Why the Cleveland Guardians will win

• The Guardians have won each of their last nine games against the Rangers at Progressive Field following a home loss.
• The Rangers have lost seven of their last eight games after playing the previous day.
• The Guardians have covered the run line in each of their last nine games against the Rangers at Progressive Field following a home loss.
• The Rangers have failed to cover the run line in seven of their last eight games after playing the previous day.
• The Guardians have led after 3 innings in each of their last four games as home favorites against AL West opponents.
• The Guardians have led after 5 innings in 12 of their last 15 night games against American League opponents.

• Probable Starting Pitcher: Jack Leiter      Record this season: 9-10      ERA: 3.92
• Road Record: 3-7
• Last 5 against Guardians: 1-1

Why the Texas Rangers will win

• The Rangers have won six of their last eight games as underdogs.
• The Guardians have lost four of their last five Friday night games as home favorites against AL West opponents.
• The underdogs have covered the run line in seven of the Rangers’ last eight games.
• The Guardians have failed to cover the run line in four of their last five games as home favorites following a loss.
• The Guardians have trailed after 5 innings in three of their last four home games against opponents that held a winning record.

Total Runs Facts

• Each of the Guardians’ last seven games as home favorites have gone UNDER the total runs line.
• Each of the Rangers’ last five games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six games as home favorites against AL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rangers’ last five night games against American League opponents.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in three of the Guardians’ last five night games against AL West opponents that held a winning record.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last eight games against AL opponents.
• Steven Kwan ranks T10th in the league in Hits (169) this season.

Texas Rangers Player Prop Facts

• Corey Seager has recorded a Double in three of his last four appearances with the Rangers as underdogs.
• Marcus Semien has recorded at least one hit in 12 of his last 13 appearances with his team as an underdog against the Guardians.
• Corey Seager has hit a home run in each of his last two appearances against AL opponents.

Matchup/League Facts

• The Guardians rank 29th in the league for on-base percentage this season (.296).
• The Guardians rank 28th in the league for slugging percentage this season (.373).
• The Rangers rank 2nd in the league for opponent batting average this season (.230).
• The Rangers rank 2nd in the league for hits allowed this season (1212).

Texas Rangers vs Cleveland Guardians Prediction

The Rangers look like a team that’s ready for vacation, as they’ve won one game since September 14. Leiter has been hit or miss his whole career, and he has a 4.41 ERA on the road this season. The Guardians are one of the hottest teams in baseball as they chase down a division crown, and they haven’t lost two straight games since September 2. Cecconi has allowed 17 hits and 9 runs in his last 26 innings, and has allowed 3 or fewer runs in 8 of his last 11 starts. Give me the Guardians on Friday, as they inch closer toward a payoff spot.