Tampa Bay Rays vs Baltimore Orioles Prediction 8/22/2026 Today’s MLB Picks

In this article, we will formulate a Rays vs Orioles Prediction for this MLB matchup on Saturday, August 22nd in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Preview

The Baltimore Orioles have a 62-67 record this season and are sitting in the 5th place of the AL East. They have a 33-33 home record and are coming off a 5-3 home win against the Rays. They will face the Cardinals and the Athletics next.

The Baltimore Orioles have a .236 batting average this season, .319 OBP and .397 Slugging percentage. Baltimore’s pitching staff has a 4.22 ERA and 1.35 WHIP. Pete Alonso is the Orioles’ best hitter with a .271 batting average, while also leading the team in RBI with 85 and adding a team-high 30 home runs.

Brandon Young (R) is the projected starting pitcher for the Orioles, and he has a 9-3 record, 3.52 ERA and 1.35 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 76-52 record this season and are sitting in the 1st place of the AL East. They have a 33-29 road record and are coming off a 3-5 road loss against the Orioles. They will face the Tigers and the Padres next.

The Tampa Bay Rays have a .261 batting average this season, .330 OBP and .406 Slugging percentage. Tampa Bay’s pitching staff has a 3.87 ERA and 1.17 WHIP. Chandler Simpson is the Rays’ best hitter with a .308 batting average. Junior Caminero leads the team in RBI with 81, while also adding a team-high 35 home runs.

Shane McClanahan (L) is the projected starting pitcher for the Rays, and he has a 9-6 record, 3.25 ERA and 1.12 WHIP.

Tampa Bay Rays @ Baltimore Orioles Betting Trends: August 22, 2026

• Probable Starting Pitcher: Brandon Young      Record this season: 9-3      ERA: 3.52
• Home Record: 2-2
• Last 5 against Rays: 0-0

Why the Baltimore Orioles will win

• The Orioles have won each of their last seven games as home underdogs against the Rays.
• The Rays have lost eight of their last nine games as road favorites against AL East opponents.
• The Rays have failed to cover the run line in each of their last nine games against AL East opponents.
• The Orioles have covered the run line in each of their last eight games against the Rays.
• The Rays have trailed after 3 innings in each of their last three games as road favorites against AL East opponents.
• The Rays have lost the first inning in each of their last three road games against AL East opponents.
• The Orioles have led after 5 innings in each of their last four games against the Rays.

• Probable Starting Pitcher: Shane McClanahan      Record this season: 9-6      ERA: 3.25
• Road Record: 2-5
• Last 5 against Orioles: 2-0

Why the Tampa Bay Rays will win

• The Rays have won nine of their last 10 road games.
• The Orioles have lost each of their last seven games as home underdogs.
• The road team has covered the run line in 20 of the Rays’ last 21 games.
• The Orioles have failed to cover the run line in each of their last five games as home underdogs.
• The Orioles have trailed after 3 innings in five of their last six home games against American League opponents that held a winning record.
• The Orioles have trailed after 5 innings in six of their last seven games as home underdogs.

Total Runs Facts

• Seven of the Rays’ last eight night games against American League opponents have gone OVER the total runs line.
• Six of the Orioles’ last seven home games have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in nine of the Rays’ last 10 games as road favorites.
• There has been no run scored during the first inning in eight of Brandon Young’s last nine home appearances as a starter.

Baltimore Orioles Player Prop Facts

• Brandon Young has recorded four or more strikeouts in each of his last nine home appearances.
• Pete Alonso has recorded at least one hit in each of the Orioles’ last 13 games.
• Dylan Beavers has hit a home run in each of the Orioles’ last three games.
• Brandon Young has recorded a win in four of his last five appearances with the Orioles as underdogs.
• Pete Alonso ranks T8th in the league in Home Runs (30) this season.

Tampa Bay Rays Player Prop Facts

• Junior Caminero has hit a home run in three of the Rays’ last four games as road favorites.
• Taylor Walls has recorded at least one hit in each of his last nine appearances with the Rays as favorites.
• Shane McClanahan has recorded a win in three of his last four appearances in night games.
• Chandler Simpson ranks 2nd in the league in Steals (35) this season.

Matchup/League Facts

• The Orioles rank 3rd in the league for walks this season (490).
• The Orioles rank 27th in the league for strikeouts against this season (1188).
• The Rays rank 1st in the league for batting average this season (.261).
• The Rays rank 1st in the league for strikeouts against this season (909).

Rays vs Orioles Prediction

The Orioles are 7-1 in their last 8 meetings against the Rays and have won their last four meetings in Baltimore.

In this Rays vs Orioles Prediction, the Rays are coming as -125 road favorites. I like the Rays in a bounce back spot today with Shane McClanahan on the mound, who has given up one run or less in four of his last six starts. On the flip side, Brandon Young has not been in good form, having given up 3+ runs in three of his last four starts and the Orioles have been terrible against lefties in their last 5 games, averaging just 2.3 runs per game. Take the Rays in this one.

Nikos Lagouretos's Pick: Tampa Bay Rays ML