St. Louis Cardinals vs Cincinnati Reds Prediction 5/24/2026 Today’s MLB Picks

The St. Louis Cardinals and Cincinnati Reds meet Sunday in MLB action at Great American Ball Park. Here’s a St. Louis Cardinals vs. Cincinnati Reds Prediction. This article will include a St. Louis Cardinals vs. Cincinnati Reds Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 29-22 on the year and play the Cubs and Brewers next. The St. Louis Cardinals are batting .242 on the season and have a .323 OBP, and a .393 slugging percentage. The St. Louis Cardinals pitching staff has a 4.20 ERA and a 1.37 WHIP. Jordan Walker leads the St. Louis Cardinals with 58 hits and 42 RBI while Alec Burleson and Ivan Herrera have combined for 108 hits and 60 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 2-2 with a 4.70 ERA and 43 strikeouts this season. Liberatore is 1-1 with a 3.32 ERA and 19 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 27-25 on the year and play the Mets and Braves next. The Cincinnati Reds are batting. 227 on the season, have a .310 OBP, and have a .393 slugging percentage. The Cincinnati Reds pitching staff has a 4.78 ERA and a 1.47 WHIP. Elly De La Cruz leads the Cincinnati Reds with 60 hits and 35 RBI, while Sal Stewart and Spencer Steer have combined for 98 hits and 52 RBI.

Brady Singer gets the ball for the Cincinnati Reds, and he is 2-4 with a 6.26 ERA and 34 strikeouts this season. Singer is 2-3 with a 3.04 ERA and 29 strikeouts in his career against the St. Louis Cardinals.

Why the Cincinnati Reds will win

• The Reds have won seven of their last eight day games after going to extra innings.
• The Cardinals have lost five of their last six day games against National League opponents that held a winning record.
• The Reds have covered the run line in five of their last six games against National League opponents.
• The Cardinals have failed to cover the run line in four of their last five day games against NL Central opponents following a loss.
• The Reds have led after 5 innings in three of their last four games.

Why the St. Louis Cardinals will win

• The underdogs have won seven of the Cardinals’ last eight games at Great American Ball Park.
• The Reds have lost each of their last four games as home favorites against National League opponents following a win.
• The Cardinals have covered the run line in each of their last nine games as road underdogs following a loss.
• The Reds have failed to cover the run line in eight of their last nine games as favorites following an extra innings win.
• The Reds have trailed after 3 innings in each of their last four home games against NL Central opponents.
• The Cardinals have led after 5 innings in four of their last five road games against NL Central opponents.

Total Runs Facts

• Seven of the Cardinals’ last eight games as road underdogs have gone UNDER the total runs line.
• Six of the Reds’ last seven games as favorites against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last eight games as home favorites against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last five road games against National League opponents.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in two of the Reds’ last three games at Great American Ball Park against opponents that held winning records.
• Brady Singer has recorded five or more strikeouts in each of his last seven Sunday appearances with his team as a favorite.
• Ke’Bryan Hayes has recorded at least one hit in eight of his last nine home appearances against the Cardinals.
• Brady Singer has recorded a win in each of his last six Sunday appearances in day games with his team as a favorite.
• Elly De La Cruz ranks T5th in the league in Hits (60) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in three of the Cardinals’ last 13 games as underdogs against NL opponents.
• Alec Burleson has recorded two hits in each of the Cardinals’ last three games as underdogs against the Reds.
• Jordan Walker ranks T6th in the league in Home Runs (15) this season.

Matchup/League Facts

• The Reds rank 27th in the league for hits this season (396).
• The Reds rank 27th in the league for batting average this season (.227).
• The Cardinals are one of only five teams in the league to rank top 10 in both strikeouts and on-base percentage this season.
• The Cardinals rank 26th in the league for opponent batting average this season (.254).

St. Louis Cardinals vs Cincinnati Reds Prediction

Not a great pitching matchup, but the Cardinals are playing the better baseball and have the slightly better pitcher. Liberatore has a 4.70 ERA and 1.55 WHIP through 51.2 innings, while Singer has a 6.26 ERA and 1.70 WHIP through 46 innings. In his last 17 innings, Singer has allowed 26 hits and 16 runs. No, thanks. The Cardinals should have a field day in this spot. Give me the Cards.

Randy Chambers's Pick: St. Louis Cardinals