St. Louis Cardinals vs Athletics Prediction 5/12/2026 Today’s MLB Picks

The St. Louis Cardinals and Athletics meet Tuesday in MLB action at Sutter Health Park. Here’s a St. Louis Cardinals vs. Athletics Prediction. This article will include a St. Louis Cardinals vs. Athletics Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 23-17 on the year and play the Royals and Pirates next. The St. Louis Cardinals are batting .235 on the season and have a .318 OBP, and a .388 slugging percentage. The St. Louis Cardinals pitching staff has a 4.25 ERA and a 1.37 WHIP. Jordan Walker leads the St. Louis Cardinals with 44 hits and 29 RBI while Alec Burleson and Ivan Herrera have combined for 79 hits and 48 RBI.

Andre Pallante gets the ball for the St. Louis Cardinals, and he is 3-3 with a 4.34 ERA and 29 strikeouts this season. This will be Pallante’s first career game against the Athletics.

Athletics Betting Preview

The Athletics are 21-19 on the year and play the Giants and Angels next. The Athletics are batting. 249 on the season, have a .326 OBP, and have a .400 slugging percentage. The Athletics pitching staff has a 4.42 ERA and a 1.44 WHIP. Shea Langeliers leads the Athletics with 50 hits and 22 RBI while Jacob Wilson and Nick Kurtz have combined for 84 hits and 39 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 3-2 with a 3.89 ERA and 39 strikeouts this season. Springs is 0-2 with a 3.15 ERA and 14 strikeouts in his career against the St. Louis Cardinals.

Why the Athletics will win

• The Cardinals have lost seven of their last eight road games against AL West opponents that held a winning record.
• The Athletics have won five of their last six night games at Sutter Health Park following a loss.
• The Cardinals have failed to cover the run line in each of their last five night games against AL West opponents that held a winning record.
• The Athletics have covered the run line in six of their last seven games following a road loss.

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last seven Tuesday games as underdogs.
• The Athletics have lost four of their last six games as favorites against NL Central opponents.
• The Cardinals have covered the run line in each of their last six road games following a loss.
• The Athletics have failed to cover the run line in five of their last six games as favorites against NL Central opponents.

Total Runs Facts

• Nine of the Athletics’ last 10 games as favorites against National League opponents have gone UNDER the total runs line.
• Each of the Cardinals’ last four road games has gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Athletics’ last 10 games as favorites.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last three games.

Athletics Player Prop Facts

• Brent Rooker has hit a home run in each of the Athletics’ last two home games against NL opponents.
• Lawrence Butler has recorded at least one hit in each of his six previous appearances in night games against NL Central teams that held a winning record.
• Shea Langeliers ranks 3rd amongst qualified players for Batting Average (.336) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in three of the Cardinals’ last six night games.
• Lars Nootbaar has recorded at least one hit in each of the Cardinals’ last six games against AL West opponents that held a winning record.
• Jordan Walker ranks 8th amongst qualified players for Slugging Percentage (.578) this season.

Matchup/League Facts

• The Athletics rank 7th in the league for batting average this season (.249).
• The Athletics rank 24th in the league for home runs allowed this season (49).
• The Cardinals rank 22nd in the league for hits this season (315).
• The Cardinals rank 22nd in the league for opponent batting average this season (.251).

St. Louis Cardinals vs Athletics Prediction

The Athletics are playing better ball right now while the Cardinals’ bats have been quiet all week. The Athletics also have the edge on the mound in this match. Pallante has a 4.34 ERA and 1.37 WHIP through 37.1 innings, while Springs has a 3.89 ERA and 1.14 WHIP through 44 innings. The Athletics are finally starting to look like the fun surprise team they were expected to be before the season. A reasonable price, I’ll side with the A’s at home.

Randy Chambers's Pick: Athletics