Seattle Mariners vs Los Angeles Angels Prediction 4/3/2026 Today’s MLB Picks

The Seattle Mariners and the Los Angeles Angels meet Friday in MLB action from Angels Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. Los Angeles Angels prediction.

Starting Pitching Matchup

The Seattle Mariners will start Bryan Woo here and Woo is 0-0 with a 3.00 ERA and 9 strikeouts this season. In his last five starts against the Mariners, Woo is 1-0 with a 3.90 ERA and 25 strikeouts. Reid Detmers will start here for the Angels and is 0-0 with a 5.79 ERA and 9 strikeouts this season. In his career, Detmers is 1-1 with a 6.39 ERA and 24 strikeouts.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to bounce back from a 5-3 loss at the hands of the Yankees last time out to sit at 3-4 this season. After this series, the Mariners will head on the road for a series against the Texas Rangers.

Mariners Lose Back-To-Back Games

Brendan Donovan has 10 hits with 2 doubles, 2 home runs and 4 RBIS while Luke Raley has 3 home runs and 6 RBIs this season. Cole Young’s added 8 hits with 2 doubles, a home run and 4 RBIs and Cal Raleigh has 4 hits with a double and 4 RBIs as well this season. Randy Arozarena has 6 hits with 3 doubles and 2 RBIs as well on the year.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to bounce back from a 6-2 loss at the hands of the Chicago Cubs last time out to sit at 3-4 this season. After this series, the Angels will take on the Atlanta Braves in a series at home.

Angels Lose 4 Of Last 5

Nolan Schanuel has 7 hits with a pair of homers and 5 RBIs while Mike Trout’s added 6 hits with 2 home runs and 3 RBIs this season. Zach Neto’s also added 6 hits with a double, 2 homers and 3 RBIs and Jo Adel has 7 hits with 2 RBIS as well this season. Oswald Peraza has 6 hits with a double, a home run and two RBIs and Jorge Soler has 4 hits with a double as well this season.

Seattle Mariners @ Los Angeles Angels Betting Trends: April 3, 2026

• Probable Starting Pitcher: Reid Detmers      Record this season: 0-0      ERA: 5.79
• Home Record: 0-0
• Last 5 against Mariners: 0-1

Why the Los Angeles Angels will win

• The Angels have won each of their last five games as home underdogs against the Mariners following a loss.
• The Mariners have lost nine of their last 12 games as favorites.
• The Mariners have failed to cover the run line each of their last eight road games against American League opponents that held a losing record.
• The Angels have covered the run line in each of their last six games as home underdogs against the Mariners following a loss.
• The Mariners have trailed after 5 innings in five of their last six road openers.
• The Angels have led after 3 innings in four of their last five games against American League opponents that held a losing record.

• Probable Starting Pitcher: Bryan Woo      Record this season: 0-0      ERA: 3.00
• Road Record: 0-0
• Last 5 against Angels: 1-0

Why the Seattle Mariners will win

• The Mariners have won each of their last eight games against AL West opponents.
• The Angels have lost each of their last six games against American League opponents following a road loss.
• The Mariners have covered the run line in 21 of their last 24 road games following a home loss.
• The Angels have failed to cover the run line in seven of their last eight night games against AL West opponents that held a losing record.
• The Mariners have led after 5 innings in each of their last six games against AL West opponents.
• The Mariners have led after 3 innings in each of their last eight games as road favorites.
• The Mariners have won the first inning in four of their last five games against AL West opponents.

Total Runs Facts

• Eight of the Mariners’ last nine games as favorites have gone OVER the total runs line.
• Each of the Angels’ last four home games against AL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Angels’ last five games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Mariners’ last five games against AL West opponents.

Los Angeles Angels Player Prop Facts

• Mike Trout has hit a home run in four of his last five home appearances against the Mariners after not playing the previous day.
• Nolan Schanuel has recorded at least one hit in each of his last nine appearances against opponents that held a losing record.
• Mike Trout ranks T7th in the league in Steals (2) this season.

Seattle Mariners Player Prop Facts

• Julio Rodriguez has recorded at least one hit in each of the Mariners’ last eight games against AL West opponents.
• Luke Raley has hit a home run in each of his last three appearances in night games.
• Brendan Donovan ranks T3rd in the league in Hits (10) this season.

Matchup/League Facts

• The Angels rank T1st in the league for home runs this season (10).
• The Angels rank 30th in the league for strikeouts against this season (80).
• The Mariners rank T3rd in the league for strikeouts this season (76).
• The Mariners rank T4th in the league for triples this season (1).

Seattle Mariners vs. Los Angeles Angels Prediction

I’m on the Mariners here. I just think there’s too much of a gap in starting pitching for the Angels to overcome here as Bryan Woo is arguably Seattle’s staff ace while the Angels are sending Detmers out for just his second start in over a year. Granted, Detmers was used out of the bullpen last year and looked good in his debut, but I just don’t trust the offense for the Halos right now against Woo so give me the Mariners to draw first blood here.

Chris Ruffolo's Pick: Seattle -160