May 14, 2025; San Francisco, California, USA; San Francisco Giants first baseman David Villar (32) tags Arizona Diamondbacks first baseman Pavin Smith (26) after he was caught in a rundown between first and second base during the ninth inning at Oracle Park. Mandatory Credit: D. Ross Cameron-Imagn Images

San Francisco Giants vs Arizona Diamondbacks Prediction 06/30/2025 Picks

Pick details

San Francisco (45-39) vs Arizona (41-42)

June 30, 2025 at 09:40 PM EDT

The Line: Betting Odds: Arizona +1.5 — Over/Under: +8

(Get latest betting odds)


The San Francisco Giants and Arizona Diamondbacks meet Monday in MLB action at Chase Field. Here’s a San Francisco Giants vs Arizona Diamondbacks Prediction. This article will include a San Francisco Giants vs Arizona Diamondbacks Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 45-39 on the year and play the Athletics, Phillies, and Dodgers next. The San Francisco Giants are batting .230 on the season, have a .313 OBP, and a .371 slugging percentage. The San Francisco Giants pitching staff has a 3.38 ERA and a 1.24 WHIP. Heliot Ramos leads the San Francisco Giants with 88 hits and 44 RBI, while Jung Hoo Lee and Wilmer Flores have combined for 143 hits and 89 RBI. 

Logan Webb gets the ball for the San Francisco Giants, and he is 7-5 with a 2.52 ERA and 120 strikeouts this season. Webb is 7-3 with a 2.31 ERA and 59 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 41-42 on the year and play the Royals, Padres, and Angels next. The Arizona Diamondbacks are batting .254 on the season, have a .329 OBP, and a .447 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.78 ERA and a 1.35 WHIP. Josh Naylor leads the Arizona Diamondbacks with 89 hits and 53 RBI while Geraldo Perdomo and Eugenio Suarez have combined for 155 hits and 125 RBI.

Ryne Nelson gets the ball for the Arizona Diamondbacks, and he is 4-2 with a 3.71 ERA and 52 strikeouts this season. Nelson is 2-0 with a 3.11 ERA and 26 strikeouts in his career against the San Francisco Giants.

Why the Arizona Diamondbacks will win

The underdogs have won each of the Diamondbacks’ last four games at Chase Field.
The Giants have lost five of their last six games as favorites.
The Diamondbacks have covered the run line in seven of their last eight games as underdogs against National League opponents.
The Giants have failed to cover the run line in eight of their last nine games as favorites following a loss.
The Giants have trailed after 5 innings in four of their last five games at Chase Field against National League opponents that held a losing record.

Why the San Francisco Giants will win

The Diamondbacks have lost each of their last five games against National League opponents following a loss.
The Giants have won each of their last nine Monday night games as road favorites against National League opponents.
The Diamondbacks have failed to cover the run line in each of their last five games at Chase Field.
The Giants have covered the run line in each of their last four night games against National League opponents following a road loss.
The Diamondbacks have trailed after 3 innings in three of their last four games as underdogs.
The Diamondbacks have trailed after 5 innings in three of their last four games as home underdogs against NL West opponents.

Arizona Diamondbacks Player Prop Facts

Eugenio Suarez has recorded a Double in three of the Diamondbacks’ last four games as underdogs against NL opponents.
Josh Naylor has recorded at least one hit in each of the Diamondbacks’ last nine home games against opponents that held a winning record.
Gabriel Moreno has hit a home run in three of his last four appearances with the Diamondbacks as underdogs against NL West opponents.
Eugenio Suarez ranks 6th amongst qualified players for Slugging Percentage (.564) this season.

San Francisco Giants Player Prop Facts

Willy Adames has hit at least one home run in three of the Giants’ last four games against NL West opponents that held a losing record.
Willy Adames has recorded at least one Double in each of his last four appearances against the Diamondbacks.
Logan Webb has recorded a win in three of his last four appearances with the Giants as favorites against the Diamondbacks.
Logan Webb has recorded six or more strikeouts in seven of his last eight appearances against NL opponents.
Wilmer Flores has recorded at least one hit in each of his last nine appearances against NL West opponents that held a losing record.
Rafael Devers ranks 6th amongst qualified players for On Base Percentage (.392) this season.

San Francisco Giants vs Arizona Diamondbacks Prediction

The Giants and Diamondbacks are coming off a poor showing over the weekend, so this is a big series to get back on the right track. Webb is the flashy name, and he’s been great this season, but he’s never as good on the road as he is at home. Webb has an ERA of 1.52 at home and a 3.75 ERA on the road. Nelson is having a solid season of his own and through 32 home innings, he has a 2.25 ERA and .207 allowed batting average. I’ll give the Diamondbacks the edge at home in this series opener.

Randy Chambers's Pick: Arizona Diamondbacks

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