San Diego Padres vs Milwaukee Brewers Prediction 5/13/2026 Today’s MLB Picks

In this article, we will formulate a Padres vs Brewers Prediction for this MLB matchup on Wednesday, May 13th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 23-16 record this season and are sitting in the second place of the NL Central. They have a 14-8 home record and are coming off a 6-4 win at home against the Padres. They will face the Twins and the Cubs next.

The Brewers have a .243 batting average this season, .334 OBP and .358 Slugging percentage. Milwaukee’s pitching staff has a 3.45 ERA and 1.24 WHIP. Brice Turang is the team’s best hitter with a .304 batting average. William Contreras leads the team in RBI with 26, and Jake Bauers adds a team‑high 6 home runs.

Jacob Misiorowski (R) is the projected starting pitcher for the Brewers, and he has a 3-2 record, 2.45 ERA and 0.95 WHIP.

San Diego Padres Preview

The San Diego Padres have a 24-17 record this season and are sitting in the first place of the NL West. They have a 11-7 away record and are coming off a 4-6 loss on the road against the Brewers. They will face the Mariners and the Rockies next.

The Padres have a .223 batting average this season, .297 OBP and .370 Slugging percentage. San Diego’s pitching staff has a 4.13 ERA and 1.24 WHIP. Xander Bogaerts is the team’s best hitter with a .267 batting average, also leading the team in RBI with 23. He adds a team‑high 7 home runs.

Michael King (R) is the projected starting pitcher for the Padres, and he has a 3-2 record, 2.76 ERA and 1.05 WHIP.

San Diego Padres @ Milwaukee Brewers Betting Trends: May 13, 2026

• Probable Starting Pitcher: Jacob Misiorowski      Record this season: 3-2      ERA: 2.45
• Home Record: 2-0
• Last 5 against Padres: –

Why the Milwaukee Brewers will win

• The Brewers have won seven of their last eight home games.
• The Padres have lost each of their last four night games against teams that held a winning record.
• The Brewers have covered the run line in eight of their last nine games against National League opponents following a home win.
• The Padres have failed to cover the run line each of their last four night games against teams that held a winning record.
• The Brewers have led after 3 innings in seven of their last eight games as home favorites against NL West opponents.
• The Brewers have led after 5 innings in five of their last six games as home favorites.

• Probable Starting Pitcher: Michael King      Record this season: 3-2      ERA: 2.76
• Road Record: 2-1
• Last 5 against Brewers: 0-2

Why the San Diego Padres will win

• The Padres have won each of their last seven road games following a loss.
• The Brewers have lost each of their last four Wednesday night games as favorites against National League opponents.
• The Padres have covered the run line in each of their last seven road games following a loss.
• The Brewers have failed to cover the run line in 14 of their last 17 home games against National League opponents after playing the previous day.
• The Padres have led after 5 innings in four of their last five night games against the Brewers at American Family Field.

Total Runs Facts

• Eight of the Padres’ last nine games after playing the previous day have gone UNDER the total runs line.
• Five of the Brewers’ last six games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Padres’ last 13 games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last five games between the Padres and Brewers at American Family Field.

Milwaukee Brewers Player Prop Facts

• Brice Turang has recorded at least one hit in each of his last 13 appearances with the Brewers as home favorites against NL West opponents.
• Andrew Vaughn has hit a home run in each of his last two appearances with the Brewers as home favorites against NL opponents.
• Jacob Misiorowski ranks 1st in the league for total Strikeouts (70) this season.

San Diego Padres Player Prop Facts

• Xander Bogaerts has hit a home run in three of the Padres’ last four games as underdogs.
• Manny Machado has recorded at least one hit in each of the Padres’ last 10 road games against the Brewers.
• Fernando Tatis Jr. ranks T9th in the league in Steals (10) this season.

Matchup/League Facts

• The Brewers rank 30th in the league for home runs this season (27).
• The Brewers rank 1st in the league for home runs allowed this season (31).
• The Padres rank 30th in the league for hits this season (300).
• The Padres rank 29th in the league for batting average this season (.223).

Padres vs Brewers Prediction

Both teams are tied 4-4 in their last 8 meetings and are 2-2 in their last 4 meetings in Milwaukee.

In this Padres vs Brewers Prediction, the Brewers are coming as -150 home favorites. Both pitchers in this matchup have been excellent with a combined 5.21 ERA and both teams also have top-11 bullpens so far, so I don’t expect a lot of runs in this game. Prior to yesterday’s game, both teams were 14-2-1 to the under in their last 17 games combined and I expect them to switch back to that trend with two red-hot pitchers on the mound. Take the under 7 runs in this one.

Nikos Lagouretos's Pick: Under 7