San Diego Padres vs Los Angeles Dodgers Prediction 8/16/2025 Today’s MLB Picks

In this article, we will formulate a Padres vs Dodgers Prediction for this MLB game on Saturday, August 16th at the Dodger Stadium in the second game of this series, with the Dodgers having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Dodgers Preview

The Los Angeles Dodgers have a 69-53 record this season and are sitting on the first place of the NL West. The Dodgers have a 39-24 home record and 60-58 in over/under. They are coming off a 3-2 home victory over the Padres, which ended their four-game losing streak. Over is 4-1-1 in their last 6 games, and are playing the Padres and the Rockies next.

The Dodgers have a .254 batting average this season, .331 OBP and .440 slugging percentage. LA’s pitching staff has a 4.15 ERA and 1.31 WHIP. Sohei Ohtani leads the Dodgers with 132 hits, in RBI, with 80 and in home runs, with 43. Freddie Freeman is the team’s best hitter with a .308 batting average.

Blake Snell (L) is the projected starting pitcher for the Dodgers, and he has a 2-1 record, 2.37 ERA and 1.53 WHIP.

San Diego Padres Preview

The San Diego Padres have a 69-53 record this season and are sitting on the second place of the NL West. They have a 31-33 road record, and are 51-68 in over/under. The Padres are coming off a 2-3 road defeat by the Dodgers, which ended their five-game winning streak. Under is 3-1 in their last 4 games and are playing the Dodgers and the Giants next.

The Padres have a .251 batting average this season, .322 OBP and .383 Slugging percentage. San Diego’s pitching staff has a 3.55 ERA and 1.20 WHIP. Manny Machado leads the Padres with 138 hits and team-high .294 batting average. He also leads the team in RBI, with 72, adding a team-high 20 home runs.

Dylan Cease (R) is the projected starting pitcher for the Padres, and he has a 5-10 record, 4.52 ERA and 1.28 WHIP.

Why the Los Angeles Dodgers will win

• The Padres have lost each of their last nine Saturday games at Dodger Stadium.
• The Dodgers have won eight of their last nine games against NL West opponents following a home win.
• The Padres have failed to cover the run line in each of their last six Saturday games at Dodger Stadium.
• The Dodgers have covered the run line in each of their last four games as favorites against NL West opponents following a win.
• The Dodgers have led after 5 innings in each of their last 11 Saturday games against the Padres.
• The Dodgers have led after 3 innings in four of their last five home games against National League opponents.

Why the San Diego Padres will win

• The Dodgers have lost each of their last five games as home favorites against National League opponents following a win.
• The Padres have won each of their last five games as underdogs after playing the previous day.
• The Padres have covered the run line in 12 of their last 13 games as underdogs.
• The Dodgers have failed to cover the run line in each of their last six home games against National League opponents following a win.
• The Padres have led after 3 innings in six of their last eight night games against NL West opponents that held a winning record.

Total Runs Facts

• Thirteen of the Padres’ last 14 night games as underdogs have gone UNDER the total runs line.
• Seven of the Dodgers’ last eight games as favorites against NL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Dodgers’ last six games against NL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Padres’ last six games as underdogs against NL West opponents.

Matchup/League Facts

• The Dodgers rank 1st in the league for RBIs this season (608).
• The Dodgers rank 2nd in the league for runs scored this season (629).
• The Padres rank 1st in the league for opponent batting average this season (.226).
• The Padres rank 1st in the league for hits allowed this season (904).

Padres vs Dodgers Prediction

The Dodgers are 8-2 in their last 10 meetings against the Padres, and are 6-2 in their 8 meetings this season. The Dodgers are also 5-1 in their last 6 meetings in Los Angeles and under is 3-0 in their last 3 meetings.

In this Padres vs Dodgers Prediction, the Dodgers are coming as -130 home favorites. The Dodgers managed to bounce back yesterday with a quality start for Kershaw, and today they are putting Snell on the mound, who is coming off a shutout start against the Blue Jays, and has been excellent overall this season, despite his injury. He has been almost unhittable at home, with a 1.29 home ERA, while Cease has been weaker on the road for the Padres, with a 5.52 road ERA. The Padres are weaker against left-handed pitching, while the Dodgers are better against righties, so I really like the Dodgers at home in a reasonable price.