Red Sox vs Yankees Prediction 8/21/2025 Today’s MLB Picks

In this article we will formulate a Red Sox vs Yankees prediction for this MLB game on Thursday, August 21st at Yankee Stadium in New York. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 68-59 this season after they lost both games against Baltimore by scores of 3-6 and 3-4. In their game two loss, Boston rallied to tie the game in the ninth, but they failed to score in the 10th and 11th for the loss. The Red Sox recorded eight hits in the game and they were led by Lowe, who went 1-4 with one home run and two RBIs in the game. Boston started Buehler, who allowed four hits and two earned runs over 4.0 innings, while Whitlock picked up the loss. 

Prior to that series, the Red Sox won two out of three against the Marlins, but did lose two out of three against the Astros before that. Boston has lost three games in a row and they are currently third in the AL East standings. The Boston pitching staff has a 3.75 ERA with a 1.30 WHIP and a .245 opponent batting average, while their offense has scored 632 runs with a .252 batting average and a .323 on base percentage this season. Wilyer Abreu has led Boston with 22 home runs and 69 RBIs, while Trevor Story has added 19 home runs and 79 RBIs this year. The projected starting pitcher for Boston is Lucas Giolito, who is 8-2 with a 3.63 ERA and a 1.25 WHIP over 106.2 innings pitched this season. 

New York Yankees Betting Preview

The New York Yankees are 69-57 this year after they won both games against Tampa Bay by scores of 13-3 and 6-4. In their game two win, New York blew a 3-1 lead in the ninth inning, but they answered with three in the 10th to secure the win. The Yankees recorded nine hits in the game and they were led by Stanton and Grisham, who both had two RBIs in the win. New York started Schlittler, who allowed one hit and zero earned runs over 6.2 innings, while Bednar blew the save, but also got the win. 

Prior to that series, the Yankees swept the Cardinals in three games and won two out of three against the Twins. New York has won seven of their last eight games and they are currently second in the AL East standings. The New York pitching staff has a 4.00 ERA with a 1.25 WHIP and a .229 opponent batting average, while the offense has scored 655 runs with a .251 batting average and a .331 on base percentage this season. Aaron Judge has led New York with 40 home runs and 92 RBIs, while Cody Bellinger has added 24 home runs and 75 RBIs this year. The projected starting pitcher for New York is Luis Gil, who is 1-1 with a 5.14 ERA and a 1.64 WHIP over 14.0 innings pitched this year.

Why the Yankees will beat the Red Sox 

• The Yankees have won each of their last 10 Thursday games at Yankee Stadium.
• The Red Sox have lost eight of their last nine games at Yankee Stadium after going to extra innings.
• The Red Sox have failed to cover the run line in each of their last five night games against AL East opponents.
• The Yankees have covered the run line in each of their last four games as favorites.
• The Yankees have led after 5 innings in each of their last six Thursday games as home favorites.
• The Red Sox have trailed after 3 innings in four of their last five games at Yankee Stadium against American League opponents that held a winning record.

Total Runs Facts

• Each of the Yankees’ last four games have gone OVER the total runs line.
• Five of the Red Sox’s last six road games against AL East opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Yankees’ last eight games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Red Sox’s last six games against AL East opponents.

New York Yankees Player Prop Facts

• Aaron Judge has hit a home run in each of his last five home appearances against AL East opponents that held a winning record.
• Cody Bellinger has recorded at least one hit in each of his last 12 appearances against AL East opponents.

Boston Red Sox Player Prop Facts

• Lucas Giolito has recorded five or more strikeouts in 12 of his last 13 road appearances against AL opponents.
• Alex Bregman has recorded at least one hit in each of his last eight appearances after not playing the previous day.
• Lucas Giolito has recorded a win in each of his last five appearances against AL opponents.
• Alex Bregman has hit at least one home run in three of his last four road appearances against AL East opponents.
• Jarren Duran has recorded a Double in three of the Red Sox’s last four games.

Red Sox vs Yankees Prediction 

New York rolls into this series on a five game winning streak and they are starting to separate from Boston in the standings. The Yankees are 37-25 at home this year, while the Red Sox are 27-34 on the road. Boston has scored exactly three runs in three straight games and they are facing Gil, who has allowed three earned runs in his last 10.2 innings. New York is red hot at the plate and they are going against Giolito, who has allowed one earned run in three of his last four starts. I don’t want to get in the way of this Yankees team right now, so I will take them at home here.