Jul 9, 2025; Boston, Massachusetts, USA; Boston Red Sox outfielder Wilyer Abreu (52) runs the bases after hitting a two-run home run against the Colorado Rockies during the fifth inning at Fenway Park. Mandatory Credit: Brian Fluharty-Imagn Images

Red Sox vs Cubs Prediction 07/19/2025 Picks

Pick details

Boston (53-46) vs Chicago (58-39)

July 19, 2025 at 07:15 PM EDT

The Line: Betting Odds: Chicago -155 — Over/Under: +9.5

(Get latest betting odds)

In this article, we will formulate a Red Sox vs Cubs prediction for this MLB game on Saturday, July 19th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 53-46 this season after they lost game one by a score of 4-1 on Friday afternoon. Boston cut the deficit to 3-1 in the third inning, but they went scoreless over the final six innings for the loss. The Red Sox recorded seven hits and they committed one error in the game, while they were led by Anthony, who went 1-3 with one RBI in the loss. Boston started Giolito, who allowed five hits and four earned runs over 5.1 innings for the loss, while Bernardino pitched 1.1 scoreless innings in relief. 

Prior to this series, the Red Sox swept the Rays in four games and also swept the Rockies in three games. Boston has won 10 of their last 11 games, and they are currently third in the AL East standings. The Boston pitching staff has a 3.80 ERA with a 1.30 WHIP and a .245 opponent batting average, while their offense has scored 492 runs with a .255 batting average and a .326 on-base percentage this season. Wilyer Abreu has led Boston with 18 home runs and 52 RBIs, while Trevor Story has added 15 home runs and 58 RBIs this year. The projected starting pitcher for Boston is Brayan Bello, who is 6-3 with a 3.14 ERA and a 1.28 WHIP over 91.2 innings pitched this season.

Chicago Cubs Betting Preview

The Chicago Cubs are 58-39 this year after they won game one by a score of 4-1 to open this series. Chicago led 3-0 in the first inning, which was enough to get the low-scoring win. The Cubs recorded six hits in the game, and they were led by Suzuki, who went 2-4 with one home run and three RBIs in the win. Chicago started Rea, who allowed four hits and one earned run over 5.0 innings for the win, while Palencia got the save. 

Prior to this series, the Cubs won two out of three against the Yankees, but did lose two out of three against the Twins before that. Chicago has won four of their last five games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.81 ERA with a 1.23 WHIP and a .246 opponent batting average, while their offense has scored 516 runs with a .255 batting average and a .325 on-base percentage this season. Seiya Suzuki has led Chicago with 26 home runs and 80 RBIs, while Pete Crow-Armstrong has added 25 home runs and 71 RBIs this year. The projected starting pitcher for Chicago is Shota Imanaga, who is 6-3 with a 2.65 ERA and a 0.93 WHIP over 68.0 innings pitched this year. 

Why the Cubs will beat the Red Sox

The favorites have won each of the Red Sox’s last 11 games.
The Red Sox have lost 11 of their last 12 road games against National League opponents that held a winning record.
The Red Sox have failed to cover the run line in seven of their last eight night games against NL Central opponents following a road loss.
The Cubs have covered the run line in four of their last five games against teams that held a winning record.
The Red Sox have trailed after 5 innings in three of their last four games as road underdogs.
The Cubs have won the first inning in four of their last five games against opponents that held a winning record.
The Cubs have led after 3 innings in 10 of their last 13 games as home favorites against AL East opponents.

Why the Red Sox will beat the Cubs

The Red Sox have won each of their last six night games after playing the previous day.
The Cubs have lost each of their last three night games against American League opponents.
The Cubs have failed to cover the run line in each of their last six night games against American League opponents following a win.
The Red Sox have covered the run line in eight of their last nine games against National League opponents after playing the previous day.
The Cubs have trailed after 3 innings in each of their last three night games against American League opponents that held a winning record.
The Red Sox have led after 5 innings in six of their last eight games against National League opponents.

Total Runs Facts

Eight of the Cubs’ last nine games against AL East opponents have gone UNDER the total runs line.
Seven of the Red Sox’s last eight games against National League opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last six games as underdogs against National League opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the Cubs’ last 15 night games at Wrigley Field.

Chicago Cubs Player Prop Facts

Shota Imanaga has recorded six or more strikeouts in each of his three previous appearances against AL East opponents that held a winning record.
Seiya Suzuki has hit at least one home run in four of the Cubs’ last five games at Wrigley Field against opponents that held a winning record.
Shota Imanaga has recorded a win in each of his three previous appearances against AL East opponents that held a winning record.
Justin Turner has recorded at least one hit in each of his last 14 appearances in night games against AL East teams that held a winning record.

Boston Red Sox Player Prop Facts

Ceddanne Rafaela has recorded at least one Double in each of the Red Sox’s last three night games against NL opponents that held a winning record.
Triston Casas has hit a home run in each of his three previous road appearances against the Cubs.
Jarren Duran has recorded at least one hit in each of the Red Sox’s last 11 games against NL opponents.

Red Sox vs Cubs Prediction 

Boston had their long winning streak come to an end on Friday afternoon, but they are back in the AL East race, and they are playing very well right now. The Red Sox are 21-26 on the road this year, while the Cubs are 31-16 at home. Chicago has allowed two runs or fewer in four of their last five games, and they are starting Imanaga, who has allowed two earned runs or fewer in four of his last five starts. The Red Sox are going with Bello, who has allowed two earned runs or fewer in three straight outings. This should be a very good pitching matchup, and I like the under, despite the wind blowing out. 

David Racey's Pick: Under 9.5

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