Jul 4, 2025; Seattle, Washington, USA; Seattle Mariners designated hitter Cal Raleigh (29) rounds the bases after hitting a solo home run during the first inning against the Pittsburgh Pirates at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images

Pittsburgh Pirates vs Seattle Mariners Prediction 07/05/2025 Picks

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Pittsburgh (38-51) vs Seattle (46-42)

July 5, 2025 at 10:10 PM EDT

The Line: Betting Odds: Seattle -1.5 — Over/Under: +7.5

(Get latest betting odds)

In this article, we will formulate a Pirates vs Mariners prediction for this MLB game on Saturday, July 5, at T-Mobile Park in Seattle, Washington. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates (38-51, 12-30 Away) went through their best period of the season, during which they won six games in a row and swept the New York Mets and St. Louis Cardinals, without allowing a single run to the Cards. That positive run ended in Game 1 of the series against the Seattle Mariners, which the Pirates lost 6-0. Bailey Falter took the loss after allowing four runs (three earned) on three hits with four strikeouts and no walks in 5.2 innings.

This year, the Pirates average 3.48 runs per game (28th in the MLB) on a .234/.306/.345 triple-slash. When it comes to pitching, the Pirates’ staff has a 3.66 ERA (8th) and 1.19 WHIP (4th). Bryan Reynolds leads the Pirates with a .235 batting average, ten home runs, and 45 RBI this season.

The projected starting pitcher for the Pirates is Mike Burrows, who is 1-2 in 18 seven this season, with a 4.15 ERA and 1.30 WHIP in 34.2 innings.

Seattle Mariners Betting Preview

The Seattle Mariners (46-42, 23-21 Home) are unbeaten in the last four series. They beat the Cubs, split with the Twins, defeated the Rangers, and split with the Royals. In the opening game of the current series against the Pirates, Seattle secured an easy 6-0 victory on Friday. Cal Raleigh led the offense with a pair of homers and three RBI, while Bryan Woo got the win after allowing no runs on three hits with eight strikeouts and two walks across 6.0 innings of work.

This season, the Mariners average 4.55 runs per game (13th in the MLB) on a .248/.323/.408 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.85 ERA (15th) and 1.26 WHIP (15th). Cal Raleigh leads the Mariners with a .271 batting average, 35 home runs, and 74 RBI this season.

Luis Castillo will take the mound for the Mariners on Saturday. The 32-year-old right-hander has a 4-5 record in 17 starts this year with a 3.55 ERA and 1.29 WHIP in 96.1 innings.

Total Runs Facts

Each of the Pirates’ last five night games as underdogs have gone OVER the total runs line.
Each of the Mariners’ last five night games against National League opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mariners’ last five games as favorites against NL Central opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Pirates’ last six night games against American League opponents.

Matchup/League Facts

The Mariners rank 26th in the league for doubles this season (121).
The Mariners rank 5th in the league for steals this season (80).
The Pirates rank T3rd in the league for home runs allowed this season (77).
The Pirates rank T27th in the league for runs scored this season (310).

Pirates vs Mariners Prediction

The Mariners won seven of the previous ten H2H encounters, and although I am leaning toward them in this one, I will opt for the Over instead. I know that betting on Over when the Pirates are involved is tricky, but the run total is now high (7.5), and I am not impressed with the way Luis Castillo and Mike Burrows play of late. Castillo allowed multiple runs in four of his previous five starts, and although Burrows had better numbers in June (a 2.73 ERA), he will be under heavy fire from Cal Raleigh and co. Three of the last four H2H duels went Over. Go with Over again.

Oliver Zivic's Pick: Over 7.5

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