Pittsburgh Pirates vs Houston Astros Prediction 6/3/2026 Today’s MLB Picks

In this article, we will formulate a Pirates vs Astros Prediction for this MLB matchup on Wednesday, June 3rd in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have a 27-35 record this season and are sitting in the 4th place of the AL West. They have a 13-17 home record and are coming off a 6-10 home defeat against the Pirates. They will face the Athletics and the Angels next.

The Astros have a .243 batting average this season, .318 OBP and .408 Slugging percentage. Houston’s pitching staff has a 4.98 ERA and 1.44 WHIP. Yordan Alvarez is the team’s best hitter with a .305 batting average, also adding a team-high 21 home runs. Christian Walker leads the team in RBI with 44.

Spencer Arrighetti (R) is the projected starting pitcher for the Astros, and he has a 7-1 record, 1.34 ERA and 1.13 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 33-28 record this season and are sitting in the 2nd place of the NL Central. They have a 15-13 road record and are coming off a 10-6 road win against the Astros. They will face the Braves and the Dodgers next.

The Pirates have a .255 batting average this season, .338 OBP and .402 Slugging percentage. Pittsburgh’s pitching staff has a 3.92 ERA and 1.25 WHIP. Nick Gonzales is the team’s best hitter with a .312 batting average. Oneil Cruz leads the team in RBI with 44, while Brandon Lowe adds a team-high 15 home runs.

Paul Skenes (R) is the projected starting pitcher for the Pirates, and he has a 6-5 record, 2.89 ERA and 0.86 WHIP.

Pittsburgh Pirates @ Houston Astros Betting Trends: June 3, 2026

• Probable Starting Pitcher: Spencer Arrighetti      Record this season: 7-1      ERA: 1.34
• Home Record: 3-0
• Last 5 against Pirates: –

Why the Houston Astros will win

• The Astros have won seven of their last eight games as underdogs against National League opponents following a loss.
• The Pirates have lost each of their last five night games against American League opponents following a road win.
• The Astros have covered the run line in eight of their last nine games as underdogs against National League opponents following a loss.
• The Pirates have failed to cover the run line in each of their last four night games against American League opponents following a road win.
• The Pirates have trailed after 3 innings in each of their last six night games against American League opponents.
• The Astros have led after 5 innings in each of their last four home night games.
• The Astros have won the first inning in each of their last five Wednesday home games against National League opponents.

• Probable Starting Pitcher: Paul Skenes      Record this season: 6-5      ERA: 2.89
• Road Record: 3-2
• Last 5 against Astros: 0-1

Why the Pittsburgh Pirates will win

• The Pirates have won each of their last 10 games as road favorites against American League opponents following a win.
• The Astros have lost six of their last seven home games against NL Central opponents.
• The Pirates have covered the run line in each of their last six road games against the Astros.
• The Astros have failed to cover the run line in each of their last five home games against the Pirates following a loss.
• The Pirates have led after 3 innings in three of their last four games against AL West opponents that held a losing record.
• The Pirates have led after 5 innings in seven of their last eight games as road favorites.

Total Runs Facts

• Each of the Astros’ last eight night games against NL Central opponents have gone OVER the total runs line.
• Each of the Pirates’ last seven games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last nine Wednesday games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Pirates’ last eight road games against American League opponents.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in four of the Astros’ last five night games against NL Central opponents that held a winning record.
• Jake Meyers has recorded at least one hit in each of his last 10 appearances against NL Central opponents that held a winning record.
• Yordan Alvarez ranks 2nd in the league in Home Runs (21) this season.

Pittsburgh Pirates Player Prop Facts

• Brandon Lowe has hit a home run in five of his last six appearances in night games against AL West teams that held a losing record.
• Brandon Lowe has recorded at least one hit in each of his last eight appearances against AL West opponents that held a losing record.
• Oneil Cruz ranks T3rd in the league in Steals (19) this season.

Matchup/League Facts

• The Astros rank T29th in the league for triples this season (3).
• The Astros rank 29th in the league for steals this season (22).
• The Pirates rank 2nd in the league for hits this season (539).
• The Pirates rank 2nd in the league for on-base percentage this season (.338).

Pirates vs Astros Prediction

The Pirates are 3-1 in their last 4 meetings against the Astros and are 3-1 in their last 4 visits in Houston.

In this Pirates vs Astros Prediction, the Pirates are coming as -155 road favorites. The Pirates are being overvalued in this spot because Skenes takes the mound, while Arrighetti has been excellent for the Astros with a dominating 7-1 record and a better ERA than Skenes. The Pirates are rolling right now, so it’s hard to fade them, even for a decent plus money price. I will take a look at the total and go under in the first five innings and trust those two pitchers to remain hot.

Nikos Lagouretos's Pick: F5 Under 3.5