Jun 18, 2025; San Francisco, California, USA; San Francisco Giants pitcher Justin Verlander (35) throws a pitch during the second inning against the Cleveland Guardians at Oracle Park. Mandatory Credit: Bob Kupbens-Imagn Images

Oakland Athletics vs San Francisco Giants Prediction 07/04/2025 Picks

Pick details

San Francisco (47-41) vs Oakland (36-53)

July 4, 2025 at 10:05 PM EDT

The Line: Betting Odds: Oakland -110 / San Francisco -110 — Over/Under: +10

(Get latest betting odds)

The San Francisco Giants are visiting the Athletics on Friday, July 4th at the Sutter Health Park in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs Athletics Prediction. We will examine:
The Athletics recent form and player performance
The San Francisco Giants recent form and player performance
Recent betting trends and streaks involving the Athletics
Recent betting trends and streaks involving the San Francisco Giants
Recent betting trends in games played between the San Francisco Giants vs Athletics
A summary that ties it all together and produces a favorable betting outcome for the San Francisco Giants vs Athletics game

Athletics Preview

The Athletics have a 36-53 record this season and are sitting on the last place of the AL West. The Athletics have a 15-27 home record and are 47-37 in over/under They are coming off a 5-6 road defeat by the Rays, and saw their previous two-game winning streak getting snapped. Over is 3-1 in their last 4 games and are playing the Braves and the Blue Jays next.

The Athletics have a .248 batting average this season, .316 OBP and .410 Slugging percentage. Athletics’ pitching staff has a 5.33 ERA and 1.48 WHIP. Jacob Wilson leads the Athletics with 108 hits and he is the team’s best hitter with a .339 batting average. Tyler Soderstrom leads the team with 48 RBI, and Brent Rooker adds a team-high 18 home runs.

JP Sears (L) is the projected starter for the Athletics, and he has a 6-7 record, 5.09 ERA and 1.30 WHIP.

San Francisco Giants Preview

The San Francisco Giants have a 47-41 record this season and are sitting on the 4th place of the NL West. They have a 22-24 road record and are 41-45 in over/under. They are coming off a 7-2 road victory over the Dbacks, and are 2-7 in their last 9 games. Over is 3-0 in their last 3 games, and are playing the Phillies and the Dodgers next.

The Giants have a .231 batting average this season, .311 OBP and .372 Slugging percentage. San Francisco’s pitching staff has a 3.40 ERA and 1.24 WHIP.  Heliot Ramos leads the Giants with 91 hits and is the team’s best hitter, with a .277 batting average, adding a team-high 13 home runs. Wilmer Flores leads the team in RBI with 55.

Justin Verlander (R) is the projected starting pitcher for the Giants, and he has a 0-5 record, 4.26 ERA and 1.39 WHIP.

Why the Athletics will win

The Giants have lost five of their last six games as road favorites against American League opponents.
The Athletics have won four of their last five games as underdogs following a road loss.
The Giants have failed to cover the run line in 10 of their last 11 games against American League opponents following a win.
The Athletics have covered the run line in 14 of their last 16 games against the Giants following a road loss.
The Giants have lost the first inning in three of their last four games against American League opponents.

Why the San Francisco Giants will win

The Giants have won each of their last seven games against AL West opponents that held a losing record.
The Athletics have lost each of their last six night games against National League opponents that held a winning record.
The Giants have covered the run line in seven of their last eight road games against AL West opponents following a road win.
The Athletics have failed to cover the run line in five of their last six night games at Sutter Health Park following a loss.
The Athletics have lost the first inning in three of their last four games against National League opponents that held a winning record.
The Athletics have trailed after 5 innings in four of their last five home games against NL West opponents that held a winning record.
The Athletics have trailed after 3 innings in each of their last six Friday games against National League opponents that held a winning record.

Total Runs Facts

Each of the Giants’ last six road games against American League opponents have gone UNDER the total runs line.
Nine of the Athletics’ last 10 night games against NL West opponents have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Giants’ last eight night games against AL West opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four night games between the Giants and Athletics.

Matchup/League Facts

The Athletics rank 30th in the league for home runs allowed this season (131).
The Athletics rank 29th in the league for ERA this season (5.33).
The Giants rank 2nd in the league for ERA this season (3.40).
The Giants rank 3rd in the league for walks this season (312).

San Francisco Giants vs Athletics Prediction

The Giants swept their previous series against the A’s this season in San Fran with 3-0 wins, bit the A’s are 3-1 in their last 4 home meetings against the Giants. Under is 6-1 in their last 7 meetings.
In this San Francisco Giants vs Athletics Prediction, both teams are coming at a pickem price. The Giants have a better overall record, and have by far more away wins than the A’s have at home. The Giants also have the best bullpen in the league, while the A’s are second to last. Verlander has been better on the road, while Sears have been weaker at home, so I like the Giants to get the job done on the road today.

Nikos Lagouretos's Pick: San Francisco Giants -110

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