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Oakland Athletics vs Cleveland Guardians Prediction 06/22/2025 Picks
Pick details
Cleveland (38-37) vs Oakland (32-47)
June 22, 2025 at 04:05 PM EDT
The Line: Betting Odds: Oakland +100 / Cleveland -120 — Over/Under: +9.5
The Cleveland Guardians are visiting the Athletics on Sunday, June 22nd at the Sutter Health Park in the third game of this series, with both teams being tied 1-1 wins. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs Athletics Prediction. We will examine:
The Athletics recent form and player performance
The Cleveland Guardians recent form and player performance
Recent betting trends and streaks involving the Athletics
Recent betting trends and streaks involving the Cleveland Guardians
Recent betting trends in games played between the Cleveland Guardians vs Athletics
A summary that ties it all together and produces a favorable betting outcome for the Cleveland Guardians vs Athletics game
Athletics Preview
The Athletics have a 32-47 record this season and are sitting on the last place of the AL West. The Athletics have a 15-26 home record and are 43-31 in over/under They are coming off a 2-4 home defeat by the Guardians, and saw their previous two-game winning streak getting snapped. They are playing the Yankees and the Tigers next.
The Athletics have a .252 batting average this season, .319 OBP and .416 Slugging percentage. Athletics’ pitching staff has a 5.45 ERA and 1.50 WHIP. Jacob Wilson leads the Athletics with 102 hits and a team-high .353 batting average, while Tyler Soderstrom leads the team with 45 RBI, and Brent Rooker adds a team-high 15 home runs.
JP Sears (L) is the projected starter for the Athletics, and he has a 5-6 record, 5.45 ERA and 1.30 WHIP. He has been weaker at home, with a 6.91 ERA across 6 home starts, and he has been in terrible form lately, having given up 4+ runs in five of his last seven starts. JP Sears is 0-2 with an ERA of 5.50 and 15 strikeouts in 4 appearances against the Guardians in his career.
Cleveland Guardians Preview
The Cleveland Guardians have a 38-36 record this season and are sitting on the second place of the AL Central. The Guardians have a 19-21 road record and are 34-37 in over/under They are coming off a 4-2 road victory over the Athletics, ending their previous two-game losing streak. Under is 6-0 in their last 6 games and are playing the Blue Jays and the Giants next.
The Guardians have a .230 batting average this season, .300 OBP and .371 Slugging percentage. Cleveland’s pitching staff has a 3.89 ERA and 1.37 WHIP. Jose Ramirez leads the Guardians with 89 hits and a team-high .324 batting average, while leading the team in home runs, with 13. Carlos Santana leads the team in RBI, with 36.
Slade Cecconi (R) is the projected starting pitcher for the Guardians, and he has a 2-3 record, 4.15 ERA and 1.35 WHIP. He has been better on the road, with a 3.43 ERA across four road starts, and he has given up 2 runs or less in four of his last five starts. In his only previous start against the A’s last season, he gave up 3 runs on 5 hits across 4 innings of work.
Why the Athletics will win
The Athletics have won five of their last six games as underdogs against AL Central opponents.
The Guardians have lost three of their last four games as road favorites.
The Athletics have covered the run line in each of their last five day games against American League opponents.
The Guardians have failed to cover the run line in each of their last four road games against AL West opponents following a win.
The Athletics have led after 3 innings in each of their last four home day games.
The Athletics have won the first inning in each of their last four day games at Sutter Health Park.
The Guardians have trailed after 5 innings in seven of their last eight road day games.
Why the Cleveland Guardians will win
The Athletics have lost each of their last 11 Sunday games against American League opponents that held a winning record.
The Guardians have won each of their last seven day games against AL West opponents following a win.
The Athletics have failed to cover the run line each of their last 10 Sunday day games against American League opponents that held a winning record.
The Guardians have covered the run line in five of their last six day games against AL West opponents that held a losing record.
The Athletics have trailed after 3 innings in seven of their last eight day games against AL Central opponents that held a winning record.
The Athletics have trailed after 5 innings in seven of their last eight day games against AL Central opponents that held a winning record.
Total Runs Facts
Each of the Guardians’ last six games have gone UNDER the total runs line.
Each of the Athletics’ last four games against AL Central opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last 10 Sunday games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last four day games at Sutter Health Park.
Matchup/League Facts
The Athletics rank 30th in the league for walks allowed this season (299).
The Athletics rank 30th in the league for home runs allowed this season (115).
The Guardians rank 29th in the league for hits this season (562).
The Guardians rank 26th in the league for slugging percentage this season (.371).
Cleveland Guardians vs Athletics Prediction
The Guardians are 10-2 in their last 12 overall meetings against the Athletics, and are 4-2 in their last 6 visits in Oakland. Over is 6-3 in their last 9 meetings.
In this Cleveland Guardians vs Athletics Prediction, the Guardians are coming as -120 road favorites. The Guardians are rightfully favored, as they have a better overall record, and they are facing an A’s team that has been terrible on the road. The A’s have by far the worst bullpen in the league, and while I trust either pitcher in this matchup, Cecconi has been looking much better than Sears. Sears has an ERA of almost 7.00 at home, and has been hit hard against Guardians bats historically. With Cleveland having the edge both at the pitcher and at the bullpen, I like them to get away with the road win today.