Apr 23, 2026; Phoenix, Arizona, USA; Chicago White Sox shortstop Colson Montgomery (12) makes the play for an out against the Arizona Diamondbacks in the first inning at Chase Field. Mandatory Credit: Rick Scuteri-Imagn Images
Rick Scuteri-Imagn Images

Nationals vs White Sox Prediction 4/26/2026 Today’s MLB Picks

Pick details

MATCHUP Washington Nationals Chicago White Sox
Team Records 12-16 11-16
Spread +1.5 -194 -1.5 159
Moneyline +109 -131
Total Over 8 (-117) Under 8 (-103)
Where Rate Field, Chicago, Illinois
When Sunday, April 26, 2026
Time 02:10 PM EDT
TV MLB.TV

In this article we will formulate a Nationals vs White Sox prediction for this MLB game on Sunday, April 26th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 12-16 this year after they split the first two games in this series by scores of 4-5 and 6-3. In game two, Washington blew a 2-0 lead in the eighth inning, but they scored four runs in the 10th to get the win. The Nationals recorded six hits and they committed one error, while they were led by Nunez, who went 2-4 with four RBIs in the game. Irvin allowed four hits and zero earned runs over 5.2 innings, while Varland blew the save and Perez got the win. Prior to this series, Washington lost three out of four against the Braves and two out of three against the Giants. 

This season, Washington has a 5.44 ERA with a 1.51 WHIP and a .269 opponent batting average, while they have scored 154 runs with a .247 batting average and a .331 on base percentage. CJ Abrams has led the Nationals with seven home runs and 20 RBIs, while James Wood has added 10 home runs and 21 RBIs. The projected starting pitcher for Washington is Foster Griffin, who is 3-0 with a 3.38 ERA and a 1.20 WHIP over 26.2 innings pitched this year. 

Chicago White Sox Betting Preview

The Chicago White Sox are 11-16 this season after they lost game two by a score of 6-3 in extra innings. Chicago scored two runs in the eighth inning to tie the game, but their pitching fell apart in the 10th for the loss. The White Sox recorded seven hits in the game and they were led by Meidroth, who went 2-3 with one RBI and one walk. Schultz allowed four hits and two earned runs over 6.0 innings, while Leasure picked up the loss in relief. Prior to this series, Chicago won two out of three against the Diamondbacks and two out of three against the Athletics. 

This season, Chicago has a 4.83 ERA with a 1.48 WHIP and a .246 opponent batting average, while they have scored 112 runs with a .226 batting average and a .319 on base percentage. Munetaka Murakami has led the White Sox with 11 home runs and 20 RBIs, while Colson Montgomery has added seven home runs and 19 RBIs. The projected starting pitcher for Chicago is Bryan Hudson, who is 0-0 with a 1.54 ERA and a 1.63 WHIP over 11.2 innings pitched this season. 

Why the Chicago White Sox will win

  • The Nationals have lost each of their last five games against American League opponents following a win.
  • The White Sox have won five of their last six day games at Rate Field after going to extra innings.
  • The White Sox have covered the run line in each of their last seven home games against National League opponents following a loss.
  • The Nationals have failed to cover the run line in each of their last five games as underdogs following a win.
  • The White Sox have led after 5 innings in three of their last four day games against National League opponents that held a losing record.

Why the Washington Nationals will win

  • The White Sox have lost each of their last five games as home favorites following an extra innings loss.
  • The underdogs have won four of the White Sox’s last six games.
  • The White Sox have failed to cover the run line in each of their last eight games as favorites against National League opponents.
  • The underdogs have covered the run line in seven of the White Sox’s last eight games.
  • The Nationals have led after 5 innings in six of their last seven road games against AL Central opponents.

Total Runs Facts

  • Five of the White Sox’s last six day games against NL East opponents have gone OVER the total runs line.
  • Eight of the Nationals’ last 10 road games against American League opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last six home games against NL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last four day games at Rate Field.

Chicago White Sox Player Prop Facts

  • Miguel Vargas has recorded at least one hit in each of the White Sox’s last six home games against NL opponents.
  • Andrew Benintendi has hit at least one home run in three of his last six home appearances against NL opponents that held a losing record.

Washington Nationals Player Prop Facts

  • CJ Abrams has hit a home run in three of the Nationals’ last nine games against AL Central opponents.
  • Keibert Ruiz has recorded at least one hit in each of his last seven Sunday day appearances against teams that held a losing record.

Nationals vs White Sox Prediction 

Washington was able to snap their losing streak with a win in extra innings on Saturday, but they have allowed 23 runs in their last four games. The Nationals are 9-6 on the road this year, while the White Sox are 4-7 at home. Chicago has won two of their last three games and they have scored at least five runs in three of their last five. Washington is starting Griffin, who has allowed three earned runs or fewer in four of his five starts, and I really like how this Washington team hits the ball, so I will take the Nationals here.

David Racey's Pick: Nationals ML

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