Nationals vs Tigers Prediction 9/22/2026 Today’s MLB Picks

In this article we will formulate a Nationals vs Tigers prediction for this MLB game on Tuesday, September 22nd at Comerica Park in Detroit, Michigan. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 73-84 this year after they lost game one by a score of 2-9 on Monday night. Washington allowed the first nine runs in the game, but they scored in the eighth to avoid being shutout. The Nationals recorded five hits and they committed one error in the game, while they were led by Morales, who went 1-1 with one home run and two RBIs. Herz allowed five hits and four earned runs over 4.0 innings for the loss, while Perales allowed five earned runs in relief. Prior to this series, Washington won two out of three against the Cardinals and split two games with the Phillies. 

This season, Washington has a 4.69 ERA with a 1.39 WHIP and a .253 opponent batting average, while they have scored 800 runs with a .247 batting average and a .322 on base percentage. CJ Abrams has led the Nationals with 31 home runs and 99 RBIs, while James Wood has added 30 home runs and 76 RBIs. The projected starting pitcher for Washington is Jackson Kent, who is 1-4 with a 6.40 ERA and a 1.76 WHIP over 32.1 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 74-83 this season after they won game one by a score of 9-2 last night. Detroit scored two runs in the first inning and never looked back in the blowout win. The Tigers recorded 12 hits in the game and they were led by Malgeri, who went 2-4 with one home run and three RBIs. Ryan allowed two hits and zero earned runs over 3.0 innings, while Montero picked up the win in relief. Prior to this series, Detroit lost three out of four against the White Sox, but did win two out of three against the Blue Jays before that. 

This season, Detroit has a 3.65 ERA with a 1.22 WHIP and a .232 opponent batting average, while they have scored 706 runs with a .241 batting average and a .319 on base percentage. Dillon Dingler has led the Tigers with 27 home runs and 89 RBIs, while Riley Greene has added 21 home runs and 75 RBIs. The projected starting pitcher for Detroit is Drew Anderson, who is 5-6 with a 3.62 ERA and a 1.29 WHIP over 102.0 innings pitched this season. 

Why the Detroit Tigers will win

• The Nationals have lost each of their last 12 games as road underdogs.
• The Tigers have won seven of their last eight games at Comerica Park against teams that held a losing record.
• The Tigers have covered the run line in eight of their last nine games against NL opponents that held a losing record.
• The Nationals have failed to cover the run line in seven of their last eight games against AL opponents that held a losing record.
• The Nationals have trailed after 3 innings in eight of their last 10 games as underdogs.
• The Nationals have trailed after 5 innings in four of their last five games as road underdogs.

Why the Washington Nationals will win

• The Tigers have lost nine of their last 10 night games against NL East opponents that held a losing record.
• The Nationals have won six of their last nine games as underdogs against AL opponents following a road loss.
• The Nationals have covered the run line in seven of their last eight games as road underdogs against AL Central opponents.
• The Tigers have failed to cover the run line in each of their last seven Tuesday night games against NL opponents.
• The Tigers have trailed after 3 innings in three of their last four home games against NL East opponents that held a losing record.
• The Nationals have led after 5 innings in three of their last four night games against the Tigers.

Total Runs Facts

• Eleven of the Nationals’ last 12 night games against AL Central opponents have gone OVER the total runs line.
• Seven of the Tigers’ last eight games as favorites against the Nationals have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Nationals’ last six night games.
• There has been at least one run scored in the first inning in each of the last four games between the Nationals and Tigers.

Detroit Tigers Player Prop Facts

• Drew Anderson has recorded four or more strikeouts in each of his last six appearances in night games.
• Spencer Torkelson has hit a home run in three of the Tigers’ last four games against the Nationals.
• Max Clark has recorded at least one hit in each of his last six appearances against opponents that held a losing record.

Washington Nationals Player Prop Facts

• Yohandy Morales has hit a home run in two of his last three appearances with the Nationals as road underdogs.
• James Wood has recorded at least one hit in each of the Nationals’ last seven games as underdogs against AL Central opponents.

Nationals vs Tigers Prediction 

Detroit was able to start this series with an easy win on Monday night and their offense finally woke up after a tough series with the White Sox. The Tigers are 40-36 at home this year, while the Nationals are 36-43 on the road. Washington has split their last four games and they have allowed 19 runs in their last three. The Nationals are starting Kent, who has allowed 3+ earned runs in four of his last five starts, while Anderson has allowed one earned run or fewer in three of his last four outings. Take the Tigers to win again here.

David Racey's Pick: Tigers ML