Jul 14, 2025; Atlanta, GA, USA; The National Anthem during the 2025 Home Run Derby at Truist Park. Mandatory Credit: Dale Zanine-Imagn Images

MLB All-Star Game Prediction 07/15/2025 Picks

Pick details

American vs National

July 15, 2025 at 08:00 PM EDT

The Line: Betting Odds: National -110 — Over/Under: 7

(Get latest betting odds)

In this article, we will formulate a MLB All-Star Game Prediction between the National League and American League on Tuesday, July 15th at Truist Park in Atlanta, Georgia. Let’s take a look at the MLB All-Star Game Prediction.

National League Betting Preview
The National League has struggled to find wins in the All Star Game over the last 11 years, but they did win in 2023 by a score of 3-2. Here are the NL starters:
C – Will Smith (LAD)
1B – Freddie Freeman (LAD)
2B – Ketel Marte (AZ)
SS – Francisco Lindor (NYM)
3B – Manny Machado (SD)
OF – Kyle Tucker (CHC)
OF – Ronald Acuna Jr. (ATL)
OF – Pete Crow-Armstrong (CHC)
DH – Shohei Ohtani (LAD)
SP – Paul Skenes (PIT)
Here are a few other notable reserves and pitchers for the National League: Pete Alonso, Elly De La Cruz, Corbin Carroll, Fernando Tatis Jr., Clayton Kershaw, Zack Wheeler, and Edwin Diaz. 

American League Betting Preview
The American League has dominated this series over the last decade, including a 5-3 win last year, where they scored the last five runs in the game after falling behind 3-0. Here are the AL starters:
C – Cal Raleigh (SEA)
1B – Vladimir Guerrero Jr. (TOR)
2B – Gleyber Torres (DET)
SS – Jacob Wilson (ATH)
3B – Junior Caminero (TB) – Jose Ramirez was the starter, but will not be playing 
OF – Riley Greene (DET)
OF – Aaron Judge (NYY)
OF – Javier Baez (DET)
DH – Ryan O’Hearn (BAL)
SP – Tarik Skubal (DET)
Here are some of the other notable reserves and pitchers for the American League: Bobby Witt Jr., Randy Arozarena, Byron Buxton, Julio Rodriguez, Jacob deGrom, Aroldis Chapman, and Josh Hader. 

MLB All-Star Game Recent History 
The American League has won 10 of the last 11 All Star Games dating back to 2013 and they have a record of 22-4-1 dating back to 1997. Here are the last 10 games that the AL has won: 5-3, 3-2, 5-2, 4-3, 8-6, 2-1, 4-2, 6-3, 5-3, and 3-0. The NL has won four games since 2010 by scores of 3-2, 8-0, 5-1, and 3-1. 

MLB All-Star Game Prediction 
We get to see the National League and the American League face off once again in the All-Star game here, but it has been a one sided rivalry over the last 25 years or so. The game is pretty meaningless and you can question how hard they try, so keep that in mind. I would say going with the AL is a smart thing to do when looking at recent results, but I actually think the NL has a slightly better team. Take the National League to get the win and make it two out of their last three. 

David Racey's Pick: National League ML

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