Jul 6, 2025; Minneapolis, Minnesota, USA; Minnesota Twins center fielder Byron Buxton (25) runs the bases on his solo home run in the first inning at Target Field. Mandatory Credit: Bruce Kluckhohn-Imagn Images

Minnesota Twins vs Chicago Cubs Prediction 07/10/2025 Picks

Pick details

Chicago (54-38) vs Minnesota (45-47)

July 10, 2025 at 01:10 PM EDT

The Line: Betting Odds: Minnesota +105 — Over/Under: +9.5

(Get latest betting odds)

The Chicago Cubs and the Minnesota Twins meet Thursday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Cubs vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Chicago Cubs will start Colin Rea here and Rea is 6-3 with a 4.13 ERA and 60 strikeouts this season. This will be Rea’s second career start against the Twins. Chris Paddack will get the nod for Minnesota here and is 3-7 with a 4.64 ERA and 68 strikeouts this season. In his career, Paddack is 1-1 with a 4.35 ERA and 13 strikeouts against the Cubs.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to rebound from a 4-2 loss at the hands of the Twins in Wednesday’s matchup to slip to 54-38 on the year. After this series, the Cubs will head on the road for a series against the New York Yankees.

Cubs Looking To Avoid Sweep

Ian Happ has 76 hits with 15 doubles, 12 home runs and 45 RBIs. Kyle Tucker has 97 hits including 18 doubles, 4 triples, 17 home runs and 55 RBIs while Seiya Suzuki also has 91 hits with 22 doubles and 25 home runs and 77 RBIs of his own. Miguel Amaya’s added 9 doubles and 25 RBIs and Pete Crow-Armstrong also has contributed 95 hits, 20 doubles, 4 triples, 23 home runs and 67 RBIs as well this season. Dansby Swanson has added 15 home runs and 42 RBIs, while also having 100 strikeouts and Suzuki has a team-high 106 strikeouts so far this season. Crow-Armstrong also has a team-high 27 stolen bases while Nico Hoerner has 16 stolen bases this season. Tucker’s also added 22 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 18 home runs and 56 RBIs this season.

Why the Chicago Cubs will win

The Cubs have won each of their last 10 day games following a road loss.
The Twins have lost six of their last seven day games against NL Central opponents.
The Twins have failed to cover the run line in 12 of their last 13 day games following a win.
The Cubs have covered the run line in each of their last six games as favorites against AL Central opponents following a loss.

Chicago Cubs Player Prop Facts


Carson Kelly has hit a home run in each of the Cubs’ last two day games.
Dansby Swanson has recorded at least one hit in each of the Cubs’ last 10 games as favorites.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to build on their win over the Cubs from Wednesday to sit at 45-47 on the year. After this series, the Twins will welcome the Pittsburgh Pirates to town.

Twins Win 4 Of Their Last 5

Byron Buxton has 77 hits along with 12 doubles, a team-high 20 home runs and 53 RBIs with 17 stolen bases and 3 triples while Carlos Correa has 77 hits with 16 doubles and Willi Castro has 64 hits with 14 doubles as well. Harrison Bader’s added 11 home runs and 34 RBIs while Buxton’s contributed a team-high 85 strikeouts as well this season. Ty France has also added 80 hits, 16 doubles, 6 home runs and 42 RBIs and Trevor Larnach’s chipped in 80 hits with 15 doubles, 12 home runs and 39 RBIs as well this season.

Why the Minnesota Twins will win

The Twins have won each of their last five games as underdogs following a home win.
The Cubs have lost seven of their last eight road games against AL Central opponents.
The Cubs have failed to cover the run line in eight of their last nine games against teams that held a losing record.
The Twins have covered the run line in seven of their last eight games as home underdogs against NL Central opponents.

Minnesota Twins Player Prop Facts

Chris Paddack has recorded five or more strikeouts in each of his last four home appearances against NL opponents that held a winning record.
Carlos Correa has recorded at least one hit in each of his last 12 appearances with the Twins as home underdogs.
Byron Buxton has hit at least one home run in three of the Twins’ last four games as underdogs against NL Central opponents.
Ryan Jeffers has recorded at least one Double in five of his last six appearances with the Twins as home underdogs.

Total Runs Facts

Each of the Cubs’ last seven road games against AL Central opponents have gone UNDER the total runs line.
Each of the Twins’ last five games against National League opponents have gone UNDER the total runs line.

Chicago Cubs vs. Minnesota Twins Prediction

I’m on the Cubs in this one. I get the case to be made for the Twins but the thing is that the Cubs are hitting well against righties for the most part this season and Chris Paddack is not a pitcher I’m willing to trust, home or away right now. Rea has been a decent option for the Cubs this season and I think that the Cubs salvage something from this series. Give me the Cubbies in this one.

Chris Ruffolo's Pick: Chicago Cubs -125

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