Jul 15, 2025; Cumberland, Georgia, USA; National League pitcher Jacob
Misiorowski of the Milwaukee Brewers pitches  during the eighth inning during the 2025 MLB All Star Game at Truist Park. Mandatory Credit: Dale Zanine-Imagn Images

Milwaukee Brewers vs Seattle Mariners Prediction 07/22/2025 Picks

Pick details

Milwaukee (60-40) vs Seattle (53-47)

July 22, 2025 at 09:40 PM EDT

The Line: Betting Odds: Seattle -1.5 — Over/Under: 7

(Get latest betting odds)

In this article, we will formulate a Brewers vs Mariners prediction for this MLB game on Tuesday, July 22, at T-Mobile Park in Seattle, Washington. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (60-40, 27-23 Away) continue with a red-hot form after winning their 11th consecutive game last night in Seattle. Before this, the Brewers swept the Dodgers twice and the Nationals, while on Monday, they secured a comfortable 6-0 victory over the Mariners. Jackson Chourio led the offense with two RBI, while Brandon Woodruff got the win after allowing no runs on two hits with five strikeouts and no walks across 6.0 innings of work.

This season, the Brewers average 4.79 runs per game (7th in the MLB) on a .250/.325/.385 triple-slash. When it comes to pitching, the Brewers’ staff has a 3.62 ERA (5th) and 1.23 WHIP (10th). Christian Yelich leads the Brewers with a .261 batting average, 19 home runs, and 66 RBI this season.

Jacob Misiorowski will take the mound for the Brewers on Tuesday. The 23-year-old right-hander has a 4-1 record in five starts this year with a 2.81 ERA and 0.90 WHIP in 25.2 innings.

Seattle Mariners Betting Preview

The Seattle Mariners (53-47, 27-23 Home) finished the first half with a sweep of the Detroit Tigers and started the second half with a victory against the Houston Astros. Seattle failed to score a single run in a 6-0 defeat to the Brewers in Game 1 of the current series. The Mariners were outhit 10-5, while George Kirby took the loss after allowing four runs on five hits with three strikeouts and one walk in 6.0 innings.

This year, the Mariners average 4.67 runs per game (8th in the MLB) on a .249/.325/.415 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.94 ERA (15th) and 1.26 WHIP (17th). Cal Raleigh leads the Mariners with a .255 batting average, 38 home runs, and 83 RBI this season.

The projected starting pitcher for the Mariners is Logan Gilbert, who is 2-3 in 12 starts this season, with a 3.39 ERA and 1.05 WHIP in 61.0 innings.

Total Runs Facts

Nine of the Mariners’ last 10 home games against NL Central opponents have gone UNDER the total runs line.
Ten of the Brewers’ last 12 night games against American League opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last six road games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last six games at T-Mobile Park.

Matchup/League Facts

The Mariners are one of only three teams in the league to rank top 10 in both steals and home runs this season.
The Mariners rank 27th in the league for strikeouts against this season (886).
The Brewers rank 5th in the league for opponent batting average this season (.232).
The Brewers rank 5th in the league for hits allowed this season (771).

Brewers vs Mariners Prediction

The Brewers won seven of the previous ten H2H encounters, including the last two. I am not sure who’s going to win this one, but I am pretty certain we will have another low-scoring affair, much tighter than on Monday. Jacob Misiorowski is enjoying a great rookie season so far; he hasn’t allowed more than two runs in four of his five starts, while he’s coming from a 12-strikeout performance against the Dodgers. Logan Gilbert, on the other hand, spent some time on the sidelines due to an injury, but he is pitching well in July, allowing five runs in three starts. Gilbert surrendered zero earned runs in the latest win over Detroit. Go with Under.

Oliver Zivic's Pick: Under 7.5

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