Los Angeles Angels vs New York Yankees Prediction 4/16/2026 Today’s MLB Picks

The Los Angeles Angels and the New York Yankees meet Thursday in MLB action from Yankee Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Angels vs. New York Yankees prediction.

Starting Pitching Matchup

The Los Angeles Angels did not have a starting pitcher announced at the time that this article was posted. The New York Yankees will start Max Fried here and Fried is 2-0 with a 1.93 ERA and 20 strikeouts this season. This will be Fried’s first career start against the Angels. 

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to bounce back from a 5-4 loss at the hands of the Yankees last time out to sit at 9-10 this season. After this series, the Angels will head home for a series against the San Diego Padres.

Angels Alternate Wins & Losses In 7 Straight

Going into Wednesday, Nolan Schanuel has 13 hits with 2 doubles, a pair of homers and 11 RBIs while Mike Trout’s added 14 hits with 3 doubles, 5 home runs and 13 RBIs this season. Zach Neto’s also added 17 hits with 3 doubles, 5 homers and 9 RBIs and Jo Adell has 23 hits with 2 home runs and 8 RBIs as well this season. Oswald Peraza has 12 hits with 2 doubles, 3 home runs and 5 RBIs and Jorge Soler has 15 hits with 3 doubles, 5 home runs and 18 RBIs well this season.

New York Yankees Recap

The New York Yankees come into this game looking to add on to their win over the Angels last time out to sit at 10-9 this season. After this series, the Yankees will take on the Kansas City Royals in a series at home.

Yankees Looking For Consistency

Giancarlo Stanton has 17 hits with 3 doubles, a home run and 8 RBIs while Ben Rice has 17 hits with 6 doubles, 4 home runs and 13 RBIs and Aaron Judge has 15 hits with 2 doubles, 6 home runs and 12 RBIs. Cody Bellinger also has 14 hits with a double, a triple, a home run and 6 RBIs.

Los Angeles Angels @ New York Yankees Betting Trends: April 16, 2026

• Probable Starting Pitcher: Max Fried      Record this season: 2-0      ERA: 1.93
• Home Record: 0-0
• Last 5 against Angels: –

Why the New York Yankees will win

• The Angels have lost each of their last eight day games against AL East opponents that held a winning record.
• The home team has won five of the Yankees’ last six games.
• The Angels have failed to cover the run line in five of their last six day games against teams that held a winning record.
• The Yankees have covered the run line in each of their last four day games against the Angels at Yankee Stadium following a win.
• The Yankees have won the first inning in five of their last six day games at Yankee Stadium.
• The Yankees have led after 5 innings in each of their last seven day games against the Angels at Yankee Stadium.
• The Yankees have led after 3 innings in seven of their last eight home day games.

• Probable Starting Pitcher: TBD

Why the Los Angeles Angels will win

• The Yankees have lost each of their last six games as favorites against AL West opponents following a win.
• The Angels have won each of their last three games as road underdogs following a loss.
• The Angels have covered the run line in each of their last nine games as underdogs against AL East opponents.
• The Yankees have failed to cover the run line in each of their last nine games after playing the previous day.
• The Angels have led after 5 innings in four of their last five games against American League opponents.

Total Runs Facts

• Each of the Angels’ last six day games after playing the previous day have gone OVER the total runs line.
• Nine of the last 10 games between the Angels and Yankees have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last 10 day games against AL East opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the last 10 day games between the Angels and Yankees at Yankee Stadium.

New York Yankees Player Prop Facts

• Max Fried has recorded seven or more strikeouts in four of his last five home appearances against AL opponents that held a losing record.
• Aaron Judge has hit at least one home run in three of the Yankees’ last four games.
• Amed Rosario has recorded at least one hit in each of his last eight appearances with his team as a favorite against the Angels.
• Max Fried has recorded a win in each of his last four appearances in day games against teams that held a losing record.
• Max Fried ranks T9th in the league for Wins (2) this season.

Los Angeles Angels Player Prop Facts

• Mike Trout has hit at least one home run in each of the Angels’ last five games as underdogs against AL East opponents.
• Mike Trout has recorded at least one hit in each of his last 11 appearances against the Yankees.
• Jo Adell ranks T6th in the league in Hits (23) this season.

Matchup/League Facts

• The Yankees rank T2nd in the league for walks allowed this season (47).
• The Yankees rank 3rd in the league for steals this season (22).
• The Angels rank 1st in the league for walks this season (88).
• The Angels rank 2nd in the league for home runs this season (29).

Los Angeles Angels vs. New York Yankees Prediction

I’m on the Yankees in this one. I get the case to be made for the Angels who have been competitive in this series, but Fried is the Yankees’ ace, and I think he shows up to help the Yankees win this series so give me New York in this one.

Chris Ruffolo's Pick: New York Yankees -275