Kansas City Royals vs Chicago White Sox Prediction 8/25/2025 Today’s MLB Picks

In this article, we will formulate a Royals vs White Sox Prediction for this MLB game on Monday, August 25th at the Rate Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 47-83 record this season and are sitting on the last place of the AL Central. The White Sox have a 28-37 home record and are 59-63 in over/under. They are coming off an 8-0 home victory over the Twins, and have back-to-back wins. Over is 4-2 in their last 6 games and are playing the Twins and the Yankees next.

The White Sox have a .233 batting average this season, .303 OBP and .372 Slugging percentage. Chicago’s pitching staff has a 4.16 ERA and 1.37 WHIP. Lenyn Sosa leads the White Sox with 110 hits, and he is the team’s best hitter with a .270 batting average. He also leads the team in RBI with 57, adding a team-high 17 home runs.

Shane Smith (R) is the projected starting pitcher for the White Sox, and he has a 3-7 record, 4.12 ERA and 1.29 WHIP.

Kansas City Royals Preview

The Kansas City Royals have a 67-64 record this season and are sitting on the second place of the AL Central. The Royals have a 31-34 road record and are 57-73 in over/under. They are coming off a 10-8 road victory over the Tigers, which ended their previous two-game losing streak. Over is 4-1 in their last 5 games and are playing the Tigers and the Angels next.

The Royals have a .247 batting average this season, .308 OBP and .395 Slugging percentage. Kansas’ pitching staff has a 3.65 ERA and 1.25 WHIP. Bobby Witt Jr. leads the Royals with 151 hits, while Maikel Garcia is the team’s best hitter with a .300 batting average. Vinnie Pasquantino leads the team in RBI, with 92, and a team-high 28 home runs.

Noah Cameron (R) is the projected starter for the Royals, and he has a 7-5 record, 2.53 ERA and 1.07 WHIP.

Why the Chicago White Sox will win

• The Royals have lost each of their last seven road games against AL Central opponents following a win.
• The home team has won nine of the last 10 games between the Royals and White Sox.
• The Royals have failed to cover the run line in each of their last seven road games against AL Central opponents following a win.
• The White Sox have covered the run line in each of their last six home games after playing the previous day.
• The White Sox have won the first inning in three of their last four games against AL Central opponents.
• The White Sox have led after 5 innings in three of their last four games against American League opponents.
• The White Sox have led after 3 innings in each of their last four games against American League opponents.

Why the Kansas City Royals will win

• The White Sox have lost each of their last 13 Monday night games against AL Central opponents.
• The Royals have won 22 of their last 25 games against the White Sox.
• The Royals have covered the run line each of their last eight Monday games against AL Central opponents that held a losing record.
• The White Sox have failed to cover the run line in seven of their last eight night games against the Royals following a win.
• The Royals have led after 3 innings in five of their last six games as favorites against American League opponents.
• The Royals have won the first inning in five of their last six night games against opponents that held a losing record.
• The Royals have led after 5 innings in five of their last six night games against opponents that held a losing record.

Total Runs Facts

• Each of the Royals’ last six games as favorites against AL Central opponents have gone UNDER the total runs line.
• Four of the White Sox’s last five night games as underdogs have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Royals’ last 10 games as favorites.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four games between the Royals and White Sox.

Matchup/League Facts

• The White Sox rank 29th in the league for walks allowed this season (477).
• The White Sox rank T28th in the league for hits this season (1003).
• The Royals rank 2nd in the league for strikeouts against this season (896).
• The Royals rank 29th in the league for walks this season (345).

Royals vs White Sox Prediction

The Royals are 8-2 in their last 10 meetings against the White Sox, but the White Sox are 2-1 in their last 3 meetings in Chicago. Under is 7-3 in their last 10 meetings.

In this Royals vs White Sox Prediction, the Royals are coming as -135 road favorites. The Royals have the pitching advantage with Cameron on the mound, who has been elite this season, and even better on the road, with a 2.11 road ERA. He has been in excellent form lately, having given up just 3 runs in 14.5 inning pitched across his last three starts. On top of that, Kansas City has a better bullpen to back him up, so I like the guests to get away with the win for a decent price in this one.