Guardians vs Cubs Prediction 07/03/2025 Picks

In this article we will formulate a Guardians vs Cubs prediction for this MLB game on Thursday, July 3rd at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview
The Cleveland Guardians are 40-44 this season after they lost the first two games in this series by scores of 2-5 and 4-5. In their game two loss, Cleveland led 3-0 in the third inning, but they allowed the next five runs for the loss. The Guardians recorded seven hits in the game and they were led by Fry, Santana, and Thomas, who all had solo home runs. Cleveland started Bibee, who allowed six hits and five earned runs over 4.0 innings for the loss, while three relievers combined for 4.0 scoreless innings. 

Prior to this series, the Guardians lost all three against the Cardinals and two out of three against the Blue Jays. Cleveland has lost seven of their last eight games and they are currently third in the AL Central standings. The Cleveland pitching staff has a 4.07 ERA with a 1.39 WHIP and a .254 opponent batting average, while the offense has scored 309 runs with a .225 batting average and a .297 on base percentage this season. Jose Ramirez has led Cleveland with 13 home runs and 38 RBIs, while Kyle Manzardo has added 13 home runs and 33 RBIs this year. The projected starting pitcher for Cleveland is Luis Ortiz, who is 4-9 with a 4.36 ERA and a 1.38 WHIP over 88.2 innings pitched this season. 

Chicago Cubs Betting Preview
The Chicago Cubs are 51-35 this year after they won game two by a score of 5-4 on Wednesday night. Chicago fell behind early in the game, but they responded with a big third and fourth inning, and they were able to hang on for the win. The Cubs recorded nine hits and they committed one error in the game, while they were led by Suzuki, who went 2-3 with three RBIs in the win. Chicago started Imanaga, who allowed four hits and three earned runs over 5.1 innings for the win, while Palencia picked up the save. 

Prior to this series, the Cubs lost two out of three against the Astros and split four games with the Cardinals. Chicago has won five of their last seven games and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.83 ERA with a 1.24 WHIP and a .247 opponent batting average, while their offense has scored 463 runs with a .257 batting average and a .327 on base percentage this season. Seiya Suzuki has led Chicago with 23 home runs and 73 RBIs, while Pete Crow-Armstrong has added 21 home runs and 64 RBIs this year. The projected starting pitcher for Chicago is Cade Horton, who is 3-2 with a 4.80 ERA and a 1.44 WHIP over 45.0 innings pitched this year. 

Why the Cubs will beat the Guardians
The Cubs have won 12 of their last 13 games against AL Central opponents that held a losing record.
The Guardians have lost each of their last six games.
The Guardians have failed to cover the run line in seven of their last eight games.
The Cubs have covered the run line in six of their last seven games against American League opponents that held a losing record.
The Guardians have trailed after 5 innings in each of their last five night games against NL Central opponents.
The Guardians have trailed after 3 innings in five of their last six games against opponents that held a winning record.

Why the Guardians will beat the Cubs
The Cubs have lost five of their last six games against American League opponents following a win.
The Cubs have failed to cover the run line in each of their last six games as favorites against the Guardians following a win.
The Guardians have covered the run line in six of their last seven games as road underdogs following a road loss.
The Cubs have trailed after 3 innings in three of their last four night games against American League opponents.

Total Runs Facts
Seven of the Guardians’ last eight road games against National League opponents have gone UNDER the total runs line.
Ten of the Cubs’ last 12 home games against American League opponents have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last 10 night games between the Guardians and Cubs.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last seven games at Wrigley Field.

Guardians vs Cubs Prediction 
Chicago has won the first two games in this series and they are going for the series sweep with a win here. The Cubs are 27-15 at home this year, while the Guardians are 20-24 on the road. Cleveland continues to really struggle over their last ten games and they are now 12.5 games behind Detroit in the Central. The Guardians are starting Ortiz, who has allowed at least four earned runs in three of his last four starts. Chicago is going with Horton, who has allowed 7, 3, 0, and 4 earned runs in his last four outings. Take the over here.