Jun 30, 2024; Chicago, Illinois, USA; Colorado Rockies outfielder Brenton Doyle (9) makes a catch against Chicago White Sox outfielder Luis Robert Jr. (not pictured) during the sixth inning at Guaranteed Rate Field. Mandatory Credit: David Banks-Imagn Images

Colorado Rockies vs Chicago White Sox Prediction 07/04/2025 Picks

Pick details

Chicago (28-59) vs Colorado (20-67)

July 4, 2025 at 08:10 PM EDT

The Line: Betting Odds: Colorado +105 / Chicago -125 — Over/Under: +11

(Get latest betting odds)

The Chicago White Sox are visiting the Colorado Rockies on Friday, July 4th at the Coors Field in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs Colorado Rockies Prediction. We will examine:
The Colorado Rockies recent form and player performance
The Chicago White Sox recent form and player performance
Recent betting trends and streaks involving the Colorado Rockies
Recent betting trends and streaks involving the Chicago White Sox
Recent betting trends in games played between the Chicago White Sox vs Colorado Rockies
A summary that ties it all together and produces a favorable betting outcome for the Chicago White Sox vs Colorado Rockies game

Colorado Rockies Preview

The Colorado Rockies have a 20-67 record this season and are sitting on the last place of the NL West. The Rockies have a 9-34 home record and are 35-49 in over/under. They are coming off a 7-6 home victory over the Astros, and are 2-7 in their last 9 games. Under is 4-1 in their last 5 games, and are playing the Reds and the Red Sox next.

The Rockies have a .231 batting average this season, .292 OBP and .381 Slugging percentage. Colorado’s pitching staff has a 5.50 ERA and 1.56 WHIP. Hunter Goodman leads the Rockies with 85 hits, adding a team-high 50 RBI, and he is the team’s best hitter with a .286 batting average. He also adds a team-high 16 home runs.

Antonio Senzatela (R) is the projected starting pitcher for the Rockies, and he has a 3-11 record, 6.69 ERA and 1.93 WHIP.

Chicago White Sox Preview

The Chicago White Sox have a 28-59 record this season and are sitting on the last place of the AL Central. The White Sox have a 9-35 road record and are 37-45 in over/under. They are coming off a 2-6 road defeat by the Dodgers, and have three consecutive losses. Over is 6-0 in their last 6 games and are playing the Blue Jays and the Guardians next.

The White Sox have a .220 batting average this season, .292 OBP and .342 Slugging percentage. Chicago’s pitching staff has a 4.13 ERA and 1.39 WHIP. Lenyn Sosa leads the White Sox with 68 hits, while Miguel Vargas leads the team in RBI, with 34, in home runs, with 9, while being the team’s best hitter with a team-high .220 batting average.

Adrian Houser (R) is the projected starter for the White Sox, and he has a 3-2 record, 1.90 ERA and 1.17 WHIP.

Why the Colorado Rockies will win

The White Sox have lost each of their last 10 night games against NL West opponents.
The home team has won each of the White Sox’s last five games.
The White Sox have failed to cover the run line in seven of their last eight night games against National League opponents.
The Rockies have covered the run line each of their last five games against teams that held a losing record.
The Rockies have led after 3 innings in five of their last six night games against American League opponents that held a losing record.
The Rockies have led after 5 innings in each of their last four games against the White Sox at Coors Field.
The White Sox have lost the first inning in six of their last eight games at Coors Field against National League opponents that held a losing record.

Why the Chicago White Sox will win

The Rockies have lost each of their last eight games against American League opponents following a win.
The White Sox have won three of their last four games against the Rockies.
The Rockies have failed to cover the run line in each of their last five games as underdogs against AL Central opponents.
The White Sox have covered the run line in five of their last six road games following a loss.
The White Sox have led after 3 innings in five of their last six night games against National League opponents that held a losing record.
The White Sox have led after 5 innings in each of their last five night games against National League opponents that held a losing record.
The Rockies have lost the first inning in four of their last five night games against American League opponents.

Total Runs Facts

Seven of the White Sox’s last eight games as favorites against NL West opponents have gone OVER the total runs line.
Each of the Rockies’ last four home games against AL Central opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last nine night games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last eight games against American League opponents.

Matchup/League Facts

The Rockies rank 1st in the league for triples this season (25).
The Rockies rank 30th in the league for on-base percentage this season (.292).
The White Sox rank 30th in the league for RBIs this season (279).
The White Sox rank 30th in the league for batting average this season (.220).

Chicago White Sox vs Colorado Rockies Prediction

The White Sox are 3-1 in their last 4 overall meetings against the Rockies, but the Rockies are 3-1 in their last 4 meetings in Colorado. Over is 5-1 in their last 6 meetings.   
In this Chicago White Sox vs Colorado Rockies Prediction, the White Sox are coming as -125 road favorites. The White Sox are rightfully favored, as they have a better overall record, facing the worst team in the league. The White Sox also have a huge pitching advantage, as they are putting their best pitcher on the mound in Adrian Houser, who is going up against Antonio Senzatela, who has been terrible this season, and even weaker at home. The White Sox also have a better bullpen, while both teams are equally bad offensively. Take the Chicago White Sox for the road victory.

Nikos Lagouretos's Pick: Chicago White Sox -125

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