Cleveland Guardians vs Houston Astros Prediction 07/08/2025 Picks

In this article, we will formulate a Guardians vs Astros prediction for this MLB game on Tuesday, July 8, at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup.

Cleveland Guardians Betting Preview

The Cleveland Guardians (41-48, 21-25 Away) went through their worst period of the season, during which they suffered ten consecutive losses and failed to score in five of them. The Guardians were swept by the Cardinals, Cubs, and Tigers, but opened the series against the Astros with a 7-5 victory on Monday. Jose Ramirez led the offense with three RBI, while Tanner Bibee pitched for 4.2 innings in a no-decision, allowing four runs on four hits with three strikeouts and one walk. Matt Festa was credited with the win.

This year, the Guardians average 3.58 runs per game (26th in the MLB) on a .224/.295/.363 triple-slash. When it comes to pitching, the Guardians’ staff has a 3.97 ERA (18th) and 1.35 WHIP (24th). Jose Ramirez leads the Guardians with a .298 batting average, 15 home runs, and 42 RBI this season.

The projected starting pitcher for the Guardians is Joey Cantillo, who is 1-0 in one start this season, with a 3.41 ERA and 1.39 WHIP in 31.2 innings.

Houston Astros Betting Preview

The Houston Astros (55-36, 32-15 Home) returned home from two road series and two wins against the Colorado Rockies and Los Angeles Dodgers. Following a three-game sweep of the Dodgers, the Astros surprisingly lost Game 1 of the series against the Guardians at home, 7-5. Taylor Trammell led the offense with a three-run homer, while Colton Gordon took the loss after allowing five runs on seven hits with two strikeouts and one walk in 5.2 innings.

This season, the Astros average 4.41 runs per game (15th in the MLB) on a .260/.325/.413 triple-slash. When it comes to pitching, the Astros’ staff has a 3.52 ERA (5th) and 1.16 WHIP (1st). Isaac Paredes leads the Astros with a .257 batting average, 19 home runs, and 49 RBI this season.

Hunter Brown will take the mound for the Astros on Tuesday. The 26-year-old right-hander has a 9-3 record in nine starts this year with a 1.82 ERA and 0.90 WHIP in 104.0 innings.

Why the Astros will cover

The Astros have won each of their last nine games at Daikin Park following a home loss.
The Guardians have lost 10 of their last 11 games against teams that held a winning record.
The Astros have covered the run line in eight of their last nine night games against the Guardians following a loss.
The Guardians have failed to cover the run line in eight of their last nine night games against the Astros following a win.
The Guardians have trailed after 5 innings in nine of their last 10 Tuesday night games against opponents that held a winning record.

Total Runs Facts

Five of the Astros’ last six games as favorites against American League opponents have gone OVER the total runs line.
Four of the Guardians’ last five games against AL West opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Guardians’ last 10 games as underdogs against AL West opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Astros’ last eight games as home favorites against AL Central opponents.

Matchup/League Facts

The Astros rank 1st in the league for opponent batting average this season (.224).
The Astros rank 2nd in the league for hits allowed this season (672).
The Guardians rank 29th in the league for on-base percentage this season (.295).
The Guardians rank 28th in the league for RBIs this season (304).

Guardians vs Astros Prediction

The Astros won seven of the previous ten H2H encounters, including five of the last seven. This season, the series is tied at 2-2. I am going with the Astros to win and cover the run line in this one because they are starting Hunter Brown, one of the best AL pitchers this year. Brown hasn’t allowed more than two runs in his previous seven starts, and he already faced the Guardians this season, allowing one run in 5.1 innings in Houston’s 5-3 win. Joey Cantillo, on the other hand, is a reliever who started just one game this year, and I don’t think he will have a good time against the Astros, who have a .263 BA in 548 at-bats against southpaws.