Cleveland Guardians vs Houston Astros Prediction 07/07/2025 Picks

The Cleveland Guardians and Houston Astros meet Monday in MLB action at Daikin Park. Here’s a Cleveland Guardians vs Houston Astros Prediction. This article will include a Cleveland Guardians vs Houston Astros Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 40-48 on the year and play the White Sox, Athletics, and Orioles next. The Cleveland Guardians are batting .224 on the season, have a .295 OBP, and a .361 slugging percentage. The Cleveland Guardians pitching staff has a 3.96 ERA and a 1.36 WHIP. Steven Kwan leads the Cleveland Guardians with 99 hits and 28 RBI, while Jose Ramirez and Carlos Santana have combined for 163 hits and 77 RBI. 

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 4-9 with a 4.20 ERA and 87 strikeouts this season. Bibee is 0-0 with a 3.18 ERA and 10 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 55-35 on the year and play the Rangers, Mariners, and Diamondbacks next. The Houston Astros are batting .261 on the season, have a .326 OBP, and a .412 slugging percentage. The Houston Astros pitching staff has a 3.48 ERA and a 1.16 WHIP. Jeremy Pena leads the Houston Astros with 102 hits and 40 RBI while Jose Altuve and Jake Meyers have combined for 180 hits and 67 RBI.

Hunter Brown gets the ball for the Houston Astros, and he is 9-3 with a 1.82 ERA and 126 strikeouts this season. Brown is 0-0 with a 5.91 ERA and 16 strikeouts in his career against the Cleveland Guardians.

Why the Houston Astros will win

The Guardians have lost each of their last 10 games against teams that held a winning record.
The Astros have won 10 of their last 11 home games.
The Astros have covered the run line in five of their last six games after playing the previous day.
The Guardians have failed to cover the run line in five of their last six games against AL West opponents that held a winning record.
The Astros have led after 5 innings in four of their last five home games.

Why the Cleveland Guardians will win

The Guardians have won 22 of their last 29 games as road underdogs against American League opponents following a home loss.
The Astros have lost three of their last four night games against American League opponents following a win.
The Guardians have covered the run line in seven of their last eight games following an extra innings loss.
The Astros have failed to cover the run line in seven of their last eight games as home favorites against American League opponents.

Houston Astros Player Prop Facts

Jose Altuve has recorded at least one hit in each of his last 11 appearances against the Guardians at Daikin Park.
Jeremy Pena has hit a home run in each of the Astros’ last two games as favorites against AL opponents.

Cleveland Guardians Player Prop Facts

Carlos Santana has hit a home run in seven of his last 15 appearances with his team as a road underdog against AL West opponents.
Steven Kwan has recorded a Double in three of the Guardians’ last four games against AL opponents that held a winning record.
Will Brennan has recorded at least one hit in each of his last six appearances against AL West opponents.
Steven Kwan ranks T7th in the league in Hits (99) this season.

Cleveland Guardians vs Houston Astros Prediction

The Guardians have lost 10 straight games and have scored two or fewer runs in eight of those games. There’s no backing the Guardians in their current form. The Astros are an even stronger pick with Brown on the mound, a pitcher who has a 1.82 ERA and 0.90 WHIP, and he’s allowed just six runs in his last 36.1 innings. In 44.2 home innings, Brown has a 1.01 ERA and .144 allowed batting average. There’s only one way to go here with the way the Guardians are watching their season fall apart. Give me the Astros and the RL for max betting value.