Cincinnati Reds vs Oakland Athletics Prediction 9/12/2025 Today’s MLB Picks

In this article, we will formulate a Reds vs Athletics Prediction for this MLB game on Friday, September 12th at the Sutter Health Park the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 67-80 record this season and are sitting on the last place of the AL West. The Athletics have a 30-42 home record and are 73-68 in over/under. They are coming off a 5-4 home victory over the Red Sox, which ended their three-game losing streak. Under is 6-2 in their last 8 games and are playing the Red Sox and the Pirates next.

The Athletics have a .255 batting average this season, .320 OBP and .434 Slugging percentage. Athletics’ pitching staff has a 4.81 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 154 hits, while Jacob Wilson is the team’s best hitter with a .319 batting average. Tyler Soderstrom adds a team-high 88 RBI, while Shea Langeliers adds a team-high 30 home runs. 

J.T. Ginn (R) is the projected starter for the Athletics, and he has a 3-6 record, 4.95 ERA, and 1.34 WHIP. 

Cincinnati Reds Preview

The Cincinnati Reds have a 74-72 record this season and are sitting in the third place of the NL Central. The Reds have a 34-38 road record and are 54-84 in over/under. They are coming off a 4-2 road victory over the Padres, and are 3-1 in their last 4 games. Under is 4-0-1 in their last 5 games and are playing the Cardinals and the Cubs next.

The Reds have a .246 batting average this season, .316 OBP and .391 slugging percentage. Cincinnati’s pitching staff has a 3.91 ERA and 1.24 WHIP.  Elly De La Cruz leads the Reds with 153 hits, and in RBI, with 82, adding a team-high 19 home runs. He is also the team’s best hitter with a .266 batting average.

Brady Singer (R) is the projected starting pitcher for the Reds, and he has a 13-9 record, 3.98 ERA and 1.26 WHIP.

Cincinnati Reds @ Athletics Betting Trends: September 12, 2025

• Probable Starting Pitcher: J.T. Ginn      Record this season: 3-6      ERA: 4.95
• Home Record: 1-4
• Last 5 against Reds: 0-0

Why the Athletics will win

• The Reds have lost each of their last five night games against teams that held a losing record.
• The Athletics have won three of their last four games against the Reds.
• The Reds have failed to cover the run line in seven of their last eight games against the Athletics following a win.
• The Athletics have covered the run line in each of their last five games against the Reds.
• The Reds have lost the first inning in four of their last five road games against opponents that held a losing record.
• The Reds have trailed after 5 innings in each of their last four night games against opponents that held a losing record.
• The Athletics have led after 3 innings in four of their last five games against the Reds.

• Probable Starting Pitcher: Brady Singer      Record this season: 13-9      ERA: 3.98
• Road Record: 5-5
• Last 5 against Athletics: 1-3

Why the Cincinnati Reds will win

• The underdogs have won eight of the Athletics’ last nine games.
• The Athletics have lost each of their last five games as favorites.
• The underdogs have covered the run line in each of the Reds’ last six games.
• The Athletics have failed to cover the run line in 10 of their last 11 home games against National League opponents following a home win.
• The Athletics have lost the first inning in four of their last five night games against National League opponents that held a winning record.
• The Athletics have trailed after 5 innings in each of their last four home night games.
• The Athletics have trailed after 3 innings in each of their last six home games against NL Central opponents.

Total Runs Facts

• Each of the Athletics’ last five games as favorites have gone UNDER the total runs line.
• Each of the Reds’ last four games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last six games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Reds’ last 12 night games against AL West opponents.

Athletics Player Prop Facts

• Lawrence Butler has hit at least one home run in each of the Athletics’ last three games against the Reds.
• Zack Gelof has recorded a Double in three of his last four appearances against NL Central opponents.
• Lawrence Butler has recorded at least one hit in each of his last six home appearances.
• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.319) this season.

Cincinnati Reds Player Prop Facts

• Austin Hays has recorded at least one Double in each of his three previous road appearances against the Athletics after not playing the previous day.
• Brady Singer has recorded a win in four of his last five appearances.
• Tyler Stephenson has recorded at least one hit in each of his last 12 road appearances against AL opponents.
• Will Benson has hit a home run in each of the Reds’ last two games against the Athletics.
• Elly De La Cruz ranks T7th in the league in Steals (34) this season.

Matchup/League Facts

• The Athletics rank 2nd in the league for doubles this season (271).
• The Athletics rank 28th in the league for ERA this season (4.81).
• The Reds rank 6th in the league for opponent batting average this season (.235).
• The Reds rank 7th in the league for hits allowed this season (1148).

Reds vs Athletics Prediction

The Athletics are 3-1 in their last 4 head-to-head meetings against the Reds, but the Reds are 3-1 in their last 4 road meetings against the A’s. Over is 3-1 in their last 4 meetings.

In this Reds vs Athletics Prediction, the Athletics are coming as -120 home favorites. The Reds have the pitching advantage, the better bullpen, and are better than the A’s against righties, and we can take them at plus money. Ginn has been terrible at home for the A’s, with a 6.64 home ERA, while Singer has been red-hot for the Reds lately, with a 5-0 record and 1.80 ERA across his last 5 starts. I like the guests as road dogs in this matchup, so take the Cincinnati Reds on the moneyline for plus money.