Pick details
| MATCHUP | Chicago Cubs | San Diego Padres |
|---|---|---|
| Team Records | 17-11 | 18-9 |
| Spread | -1.5 144 | +1.5 -175 |
| Moneyline | -115 | -105 |
| Total | Over 8 (-105) | Under 8 (-115) |
| Where | Petco Park, San Diego, California | |
| When | Monday, April 27, 2026 | |
| Time | 09:40 PM EDT | |
| TV | MLB.TV | |
Chicago Cubs Betting Preview
The Chicago Cubs are 17-11 on the year and play the Diamondbacks and Reds next. The Chicago Cubs are batting .263 on the season and have a .354 OBP, and a .427 slugging percentage. The Chicago Cubs pitching staff has a 3.89 ERA and a 1.19 WHIP. Nico Hoerner leads the Chicago Cubs with 35 hits and 23 RBI, while Alex Bregman and Pete Crow-Armstrong have combined for 54 hits and 17 RBI.
Matthew Boyd gets the ball for the Chicago Cubs, and he is 1-1 with a 5.79 ERA and 22 strikeouts this season. Boyd is 1-1 with a 1.59 ERA and 8 strikeouts in his career against the San Diego Padres.
San Diego Padres Betting Preview
The San Diego Padres are 18-9 on the year and play the Giants and White Sox next. The San Diego Padres are batting. 235 on the season, have a .311 OBP, and have a .382 slugging percentage. The San Diego Padres pitching staff has a 3.96 ERA and a 1.29 WHIP. Xander Bogaerts leads the San Diego Padres with 27 hits and 16 RBI, while Ramon Laureano and Fernando Tatis Jr. have combined for 50 hits and 30 RBI.
Randy Vasquez gets the ball for the San Diego Padres, and he is 2-0 with a 1.88 ERA and 30 strikeouts this season. Vasquez is 0-1 with a 2.57 ERA and 10 strikeouts in his career against the Chicago Cubs.
Why the San Diego Padres will win
- The Padres have won each of their last eight games at Petco Park.
- The Cubs have lost seven of their last eight Monday games as road favorites against National League opponents.
- The Cubs have failed to cover the run line in eight of their last nine road games against teams that held a winning record.
- The Padres have covered the run line in seven of their last eight home games.
- The Padres have led after 5 innings in five of their last six games at Petco Park.
- The Padres have led after 3 innings in three of their last four home games.
Why the Chicago Cubs will win
- The Cubs have won each of their last eight road games against the Padres following a loss.
- The Cubs have covered the run line in seven of their last eight road games against the Padres following a loss.
- The Padres have failed to cover the run line in seven of their last eight Monday games at Petco Park.
- The Padres have trailed after 5 innings in three of their last four games.
Total Runs Facts
- Each of the Padres’ last four games as underdogs has gone UNDER the total runs line.
- Six of the Cubs’ last seven night games against National League opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last nine games as underdogs.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last seven night games at Petco Park.
San Diego Padres Player Prop Facts
- Nick Castellanos has recorded at least one hit in 18 of his last 19 appearances with his team as a home underdog against NL opponents.
- Luis Campusano has hit a home run in each of his last three appearances with the Padres against NL opponents.
Chicago Cubs Player Prop Facts
- Seiya Suzuki has hit a home run in each of the Cubs’ last two games as favorites against NL opponents.
- Matthew Boyd has recorded six or more strikeouts in three of his four previous road appearances against NL West opponents that held a winning record.
- Ian Happ has recorded at least one hit in each of his 10 previous Monday night appearances against NL West teams that held a winning record.
- Nico Hoerner ranks T9th in the league in Steals (7) this season.
Matchup/League Facts
- The Padres rank 25th in the league for hits this season (211).
- The Padres rank 6th in the league for doubles this season (51).
- The Cubs rank 3rd in the league for batting average this season (.263).
- The Cubs rank T3rd in the league for walks this season (126).
Chicago Cubs vs San Diego Padres Prediction
The Cubs are a decent team that’s worth a look, but I’ve been riding the Padres train for a while and not turning back now, especially in this matchup. We need to see a larger sample size from Boyd, as he’s pitched just 14 innings and has a 5.79 ERA and 1.14 WHIP. Through 28.2 frames, Vasquez has a 1.88 ERA and 1.08 WHIP while striking out 30. If we were getting a decent plus money price, I’d look at the Cubs more seriously. This is a pick-’em spot. Give me the Padres at home.


