Chicago Cubs vs Miami Marlins Prediction 9/6/2026 Today’s MLB Picks

In this article, we will formulate a Cubs vs Marlins Prediction for this MLB matchup on Sunday, September 6th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 71-72 record this season and are sitting in 3rd place in the NL East. They have a 42-29 home record and are coming off a 5-6 home loss against the Cubs. They will face the Mets and the Dodgers next.

The Miami Marlins have a .247 batting average this season, .325 OBP, and .398 slugging percentage. Miami’s pitching staff has a 3.99 ERA and 1.26 WHIP. Otto Lopez is the Marlins’ best hitter with a .300 batting average, while leading the team in RBI with 62, and Heriberto Hernandez leads the team with 23 home runs.

Tyler Phillips (R) is the projected starting pitcher for the Marlins, with a 4-6 record, 3.43 ERA, and 1.33 WHIP.

Chicago Cubs Preview

The Chicago Cubs have an 81-62 record this season and are sitting in 2nd place in the NL Central. They have a 40-31 road record and are coming off a 6-5 road win against the Marlins. They will face the Brewers and the Pirates next.

The Chicago Cubs have a .252 batting average this season, .340 OBP, and .432 slugging percentage. Chicago’s pitching staff has a 4.17 ERA and 1.26 WHIP. Pete Crow-Armstrong is the Cubs’ best hitter with a .279 batting average, while leading the team in RBI with 94, adding a team-high 39 home runs.

Clay Holmes (R) is the projected starting pitcher for the Cubs, with a 6-6 record, 2.09 ERA, and 1.07 WHIP.

The Chicago Cubs @ Miami Marlins Betting Trends: September 6, 2026

• Probable Starting Pitcher: Tyler Phillips      Record this season: 4-6      ERA: 3.43
• Home Record: 2-2
• Last 5 against Cubs: 0-0

Why the Miami Marlins will win

• The underdogs have won seven of the Marlins’ last 10 games.
• The Cubs have lost six of their last eight Sunday day games as road favorites against NL East opponents.
• The Marlins have covered the run line in each of their last eight games as underdogs against NL Central opponents following a home loss.
• The Cubs have failed to cover the run line in each of their last four day games following a win.
• The Marlins have led after 5 innings in each of their last six Sunday games against the Cubs.
• The Marlins have led after 3 innings in seven of their last nine day games against NL Central opponents that held a winning record.

• Probable Starting Pitcher: Clay Holmes      Record this season: 6-6      ERA: 2.09
• Road Record: 3-3
• Last 5 against Marlins: 2-0

Why the Chicago Cubs will win

• The Marlins have lost each of their last eight games against NL opponents that held a winning record.
• The Cubs have won 14 of their last 15 games against NL East opponents that held a losing record.
• The Cubs have covered the run line in six of their last seven road games against teams that held a losing record.
• The Marlins have failed to cover the run line in eight of their last 10 home games against NL opponents following a loss.
• The Cubs have won the first inning in each of their last three games against opponents that held a losing record.
• The Marlins have trailed after 5 innings in eight of their last nine games against NL opponents that held a winning record.
• The Cubs have led after 3 innings in eight of their last nine games.

Total Runs Facts

• Five of the Cubs’ last six games as favorites have gone OVER the total runs line.
• Fifteen of the Marlins’ last 20 day games against NL Central opponents have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of the Marlins’ last 12 games against NL Central opponents.
• There has been no run scored during the first inning in each of the Cubs’ last seven road games against NL opponents.

Miami Marlins Player Prop Facts

• Griffin Conine has hit a home run in four of the Marlins’ last five day games against opponents that held a winning record.
• Tyler Phillips has recorded four or more strikeouts in each of his last four home appearances.
• Javier Sanoja has recorded at least one hit in each of the Marlins’ last nine games against NL opponents that held a winning record.
• Otto Lopez ranks 2nd in the league in Hits (167) this season.

Chicago Cubs Player Prop Facts

• Pete Crow-Armstrong has hit at least one home run in three of the Cubs’ last four games against opponents that held a losing record.
• Pete Crow-Armstrong has recorded two or more hits in each of the Cubs’ last four games against opponents that held a losing record.
• Clay Holmes has recorded a win in each of his last three appearances with his team as a road favorite against NL East opponents.
• Clay Holmes has recorded five or more strikeouts in four of his last five appearances with his team as a road favorite.
• Pete Crow-Armstrong ranks 2nd in the league in Home Runs (39) this season.

Matchup/League Facts

• The Marlins rank T2nd in the league for triples this season (30).
• The Marlins rank 2nd in the league for steals this season (146).
• The Cubs rank 1st in the league for runs scored this season (765).
• The Cubs rank 1st in the league for home runs this season (200).

Cubs vs Marlins Prediction

The Cubs have won their last four meetings against the Marlins and are 4-0 in their last 4 visits in Miami.

In this Cubs vs Marlins Prediction, the Cubs are coming as -140 road favorites. I like the Cubs to keep rolling in this series with Clay Holmes on the mound, who has been excellent this season with a 2.09 ERA, and 1.07 WHIP and has been red-hot lately, having given up just one run across his last three starts. The Cubs have won both games in this series with a combined 12-6 score, their bats have been red-hot and they have both a better offense and bullpen than the Marlins this season. Take the Cubs in this one.

Nikos Lagouretos's Pick: Chicago Cubs ML