Chicago Cubs vs Kansas City Royals Prediction 07/23/2025 Picks

The Kansas City Royals and the Chicago Cubs meet Wednesday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Kansas City Royals vs. Chicago Cubs prediction.

Starting Pitching Matchup

The Kansas City Royals will send out Seth Lugo for the start here, and Lugo is 6-5 with a 2.94 ERA and 93 strikeouts this season. In his career, Lugo is 0-3 with an 8.35 ERA and 12 strikeouts against the Cubs. The Chicago Cubs did not have a starting pitcher announced at the time that this article was posted.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to rebound from a 6-0 loss at the hands of the Cubs on Tuesday to sit at 49-53 this season. After this series, the Royals will head home for a division series against the Cleveland Guardians.

Royals Looking For Series Win

Bobby Witt Jr. has 116 hits with 33 doubles and 27 stolen bases along with 3 triples, 14 home runs and 56 RBIs, while Vinnie Pasquantino has 102 hits with 14 doubles, a triple, 15 home runs and 57 RBIs. Maikel Garcia added 108 hits with 26 doubles, 3 triples, 8 home runs, and 41 RBIs, and 18 stolen bases and Salvador Perez also has 17 home runs and 60 RBIs, but also has 77 strikeouts so far this season.

Why the Kansas City Royals will win

The Royals have won five of their last six games as underdogs against NL Central opponents following a loss.
The Cubs have lost four of their last five day games following a home win.
The Royals have covered the run line in each of their last 13 games as road underdogs against National League opponents following a loss.
The Cubs have failed to cover the run line in each of their last five games against AL Central opponents following a win.

Kansas City Royals Player Prop Facts

Seth Lugo has recorded five or more strikeouts in each of his last seven road appearances.
Seth Lugo has recorded a win in three of his last four appearances with the Royals as underdogs.
Salvador Perez has hit at least one home run in three of the Royals’ last four games against NL opponents.
Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 29 road games against opponents that held a winning record.
Adam Frazier has recorded a Double in three of his last four appearances against NL opponents.
Bobby Witt Jr. ranks T3rd in the league in Hits (116) this season.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to add onto their win over the Royals from Tuesday to end at 60-41 this season. After this series, the Cubs will take on the Chicago White Sox in a crosstown rivalry matchup.

Cubs Trying To Keep Series Win Streak Alive

Ian Happ has 83 hits with 16 doubles, 13 home runs and 48 RBIs. Kyle Tucker has 102 hits including 19 doubles, 4 triples, 18 home runs and 57 RBIs while Seiya Suzuki also has 100 hits with 24 doubles and 26 home runs and 81 RBIs of his own. Pete Crow-Armstrong also has contributed 105 hits, 25 doubles, 4 triples, 26 home runs and 73 RBIs as well this season. Dansby Swanson has added 16 home runs and 47 RBIs, while also having 112 strikeouts and Suzuki has a team-high 112 strikeouts so far this season. Crow-Armstrong also has a team-high 28 stolen bases while Nico Hoerner has 19 stolen bases this season. Tucker’s also added 23 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 20 home runs and 60 RBIs this season.

Why the Chicago Cubs will win

The Cubs have won each of their last eight day games against AL Central opponents that held a losing record.
The Royals have lost each of their last four games against the Cubs following a road loss.
The Cubs have covered the run line each of their last six day games against AL Central opponents that held a losing record.
The Royals have failed to cover the run line in five of their last six games against National League opponents that held a winning record.

Chicago Cubs Player Prop Facts

Carson Kelly has hit a home run in three of his last five appearances with the Cubs as home favorites.
Dansby Swanson has recorded at least one hit in each of the Cubs’ last 12 games against AL Central opponents that held a losing record.
Pete Crow-Armstrong ranks 5th in the league in Steals (28) this season.

Total Runs Facts

Twelve of the Royals’ last 14 day games after playing the previous day have gone UNDER the total runs line.
Six of the Cubs’ last seven games as favorites against American League opponents have gone UNDER the total runs line.

Kansas City Royals vs. Chicago Cubs Prediction

I’m on the Cubs in this one. I just don’t know how much I trust Seth Lugo on the road, and against a Cubs lineup that from a talent perspective, is one of the most complete teams in the majors. The Royals are a team that continues to be hit or miss offensively, and I think the Royals are in some trouble here. Give me Chicago here.