Chicago Cubs vs Chicago White Sox Prediction 07/27/2025 Picks

The Chicago Cubs and Chicago White Sox meet Sunday in MLB action at Rate Field. Here’s a Chicago Cubs vs Chicago White Sox Prediction. This article will include a Chicago Cubs vs Chicago White Sox Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 61-43 on the year and play the Brewers, Orioles, and Reds next. The Chicago Cubs are batting .256 on the season, have a .325 OBP, and a .445 slugging percentage. The Chicago Cubs pitching staff has a 3.89 ERA and a 1.23 WHIP. Nico Hoerner leads the Chicago Cubs with 109 hits and 41 RBI, while Pete Crow-Armstrong and Kyle Tucker have combined for 211 hits and 132 RBI. 

Ben Brown gets the ball for the Chicago Cubs, and he is 4-7 with a 6.48 ERA and 95 strikeouts this season. This will be Brown’s first career game against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 38-67 on the year and play the Phillies, Angels, and Mariners next. The Chicago White Sox are batting .226 on the season, have a .299 OBP, and a .359 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.38 WHIP. Miguel Vargas leads the Chicago White Sox with 84 hits and 41 RBI, while Lenyn Sosa and Chase Meidroth have combined for 159 hits and 52 RBI.

Grant Taylor gets the ball for the Chicago White Sox, and he is 0-1 with a 3.93 ERA and 23 strikeouts this season. This will be Taylor’s first career game against the Chicago Cubs.

Why the Chicago White Sox will win

• The White Sox have won each of their last four day games against the Cubs following a home loss.
• The Cubs have lost each of their last four road games against AL Central opponents following a win.
• The White Sox have covered the run line in 10 of their last 11 day games following a loss.
• The Cubs have failed to cover the run line in each of their last four road games against AL Central opponents following a win.

Why the Chicago Cubs will win

• The White Sox have lost 15 of their last 16 day games against NL Central opponents that held a winning record.
• The Cubs have won nine of their last 10 games against the White Sox.
• The Cubs have covered the run line in six of their last seven day games against AL Central opponents that held a losing record.
• The White Sox have failed to cover the run line in each of their last four games against the Cubs following a loss.
• The Cubs have led after 3 innings in five of their last six day games against American League opponents that held a losing record.

Chicago White Sox Player Prop Facts

• Mike Tauchman has hit a home run in each of the White Sox’s last three games against NL opponents.
• Michael A. Taylor has recorded a Double in three of his last four appearances against NL Central opponents.
• Luis Robert has recorded at least one hit in each of his last nine appearances.

Chicago Cubs Player Prop Facts

• Kyle Tucker has recorded at least one hit in each of his last 11 road appearances against the White Sox.
• Ian Happ has hit a home run in three of the Cubs’ last five games against the White Sox at Rate Field.
• Carson Kelly has recorded a Double in three of his last four appearances in day games against AL teams that held a losing record.

Chicago Cubs vs Chicago White Sox Prediction

The Cubs are the better team, and the White Sox are a team we’ve blindly faded for years. However, I want nothing to do with Brown, a pitcher who has allowed 37 hits and 24 earned runs in his last 26.2 innings. In 43.2 road innings, Brown has a 6.80 ERA and .294 allowed batting average. The White Sox have played their best ball of the season over the last week, and the offense has put up numbers. They should like their chances with Brown on the bump. Give me the White Sox.