Cardinals vs Cubs Prediction 8/16/2026 Today’s MLB Picks

In this article we will formulate a Cardinals vs Cubs prediction for this MLB game on Sunday, August 16th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 62-61 this year after they split the first two games by scores of 0-3 and 8-4. In game two, St. Louis blew an early 3-0 lead, but they scored the next five runs to pull away in the win. The Cardinals recorded seven hits and they committed one error in the game, while they were led by Baez, who went 3-4 with three home runs and five RBIs. McGreevy allowed five hits and zero earned runs over 6.0 innings for the win, while Stanek allowed one earned run in relief. Prior to this series, St. Louis won two out of three against the Phillies and two out of three against the Rockies. 

This season, St. Louis has a 4.04 ERA with a 1.34 WHIP and a .252 opponent batting average, while they have scored 537 runs with a .239 batting average and a .315 on base percentage. Jordan Walker has led the Cardinals with 23 home runs and 84 RBIs, while Alec Burleson has added 20 home runs and 86 RBIs. The projected starting pitcher for St. Louis is Hunter Dobbins, who is 2-3 with a 3.40 ERA and a 1.31 WHIP over 45.0 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 72-52 this season after they lost game two by a score of 4-8 on Saturday. Chicago scored three runs in the second inning, but didn’t score again until the eighth in the loss. The Cubs recorded eight hits in the game and they were led by Conforto, who went 1-2 with one home run and three RBIs. Boyd allowed five hits and seven earned runs over 5.1 innings for the loss, while Rea allowed one earned run in relief. Prior to this series, Chicago won two out of three against the Nationals and two out of three against the Royals. 

This season, Chicago has a 4.10 ERA with a 1.25 WHIP and a .244 opponent batting average, while they have scored 641 runs with a .249 batting average and a .338 on base percentage. Pete Crow-Armstrong has led the Cubs with 27 home runs and 73 RBIs, while Dansby Swanson has added 18 home runs and 66 RBIs. The projected starting pitcher for Chicago is Edward Cabrera, who is 5-4 with a 5.10 ERA and a 1.40 WHIP over 72.1 innings pitched this season. 

Why the Chicago Cubs will win

• The Cubs have won each of their last seven day games following a loss.
• The Cardinals have lost seven of their last eight day games against National League opponents following a win.
• The Cubs have covered the run line in each of their last six home games following a loss.
• The Cardinals have failed to cover the run line in seven of their last eight day games against National League opponents following a win.

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last three games as underdogs after playing the previous day.
• The Cubs have lost six of their last eight home games against NL Central opponents.
• The Cardinals have covered the run line in each of their last five games after playing the previous day.
• The Cubs have failed to cover the run line in 12 of their last 15 home games against NL Central opponents.

Total Runs Facts

• Eight of the Cardinals’ last 10 games as road underdogs have gone UNDER the total runs line.
• Three of the Cubs’ last four games as favorites against the Cardinals have gone OVER the total runs line.
• There has been no run scored during the first inning in six of the Cardinals’ last seven games as underdogs.
• There has been at least one run scored in the first inning in four of the Cubs’ last five games as home favorites against National League opponents.

Chicago Cubs Player Prop Facts

• Seiya Suzuki has hit a home run in each of the Cubs’ last two day games against NL Central opponents that held a winning record.
• Edward Cabrera has recorded five or more strikeouts in each of his last seven Sunday day appearances against NL teams that held a winning record.
• Seiya Suzuki has recorded at least one hit in each of his last nine appearances against opponents that held a winning record.

St. Louis Cardinals Player Prop Facts

• Jordan Walker has hit a home run in four of the Cardinals’ last 11 road games against NL Central opponents.
• Hunter Dobbins has recorded four or more strikeouts in each of his last seven appearances against NL opponents.
• Blaze Jordan has recorded at least one hit in each of his last eight road appearances.

Cardinals vs Cubs Prediction

St. Louis bounced back from their game one loss with a win on Saturday and they are back above .500 for the season. The Cardinals are 30-27 on the road this year, while the Cubs are 36-25 at home. Chicago has lost two of their last three games and they have allowed 6+ runs in four of their last five. The Cubs are starting Cabrera, who has been on the IL since June, while Dobbins has allowed two earned runs or fewer in three of his last four starts. Take the Cardinals to win again here.

David Racey's Pick: Cardinals ML