Boston Red Sox vs Baltimore Orioles Prediction 4/24/2026 Today’s MLB Picks

The Boston Red Sox and the Baltimore Orioles meet Friday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Baltimore Orioles prediction.

Starting Pitching Matchup

The Boston Red Sox will start Brayan Bello here and Bello is 1-2 with a 6.75 ERA and 13 strikeouts this season. In his last five starts against Baltimore, Bello is 3-0 with a 3.00 ERA and 31 strikeouts. Brandon Young will start this one for the Orioles and is 1-0 with a 0.00 ERA and 2 strikeouts this season. This will be Young’s first career start against the Red Sox.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from their 4-2 loss at the hands of the New York Yankees last time out to sit at 9-16 this season. After this series, the Red Sox will head on the road for a series against the Toronto Blue Jays.

Red Sox Drop 5 Of Last 6

Wilyer Abreu leads the Red Sox with 26 hits including 4 doubles, a triple, 3 home runs and 11 RBIs while Trevor Story has 19 hits with 5 doubles, 2 homers and 17 RBIs and Marcelo Mayer’s added 12 hits with 5 doubles, a home run and 4 RBIs as well. Roman Anthony has 18 hits with 3 doubles, a triple, a home run and 4 RBIs so far this season while Jarren Duran has 15 hits with 5 doubles, a home run and 11 RBIs as well this season. Willson Contreras has added 21 hits with 2 doubles, 4 homers and 12 RBIs of his own on the year.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to build on their 8-6 win over Kansas City last time out to improve to 12-13 this season. After this series, the Orioles will take on the Houston Astros in a series at home.

Orioles Alternate Wins & Losses In 4 Straight

Taylor Ward has 28 hits with 13 doubles and 11 RBIs while Gunnar Henderson has 20 hits with 4 doubles, 7 home runs and 15 RBIs and Pete Alonso has 20 hits with 6 doubles, 3 home runs and 10 RBIs. Adley Rutschman has 12 hits with 6 doubles and 5 RBIs. Jeremiah Jackson has 23 hits with 2 doubles, 5 home runs and 19 RBIs while Dylan Beavers also has 14 hits with 3 doubles, a home run and 7 RBIs.

Boston Red Sox @ Baltimore Orioles Betting Trends: April 24, 2026

• Probable Starting Pitcher: Brandon Young      Record this season: 1-0      ERA: 0.00
• Home Record: 0-0
• Last 5 against Red Sox: –

Why the Baltimore Orioles will win

• The Red Sox have lost each of their last eight games as underdogs after playing the previous day.
• The Orioles have won five of their last six games against American League opponents that held a losing record.
• The Red Sox have failed to cover the run line in each of their last nine night games against American League opponents.
• The Orioles have covered the run line in seven of their last eight games against the Red Sox.
• The Red Sox have lost the first inning in each of their last six road games against American League opponents.
• The Red Sox have trailed after 3 innings in five of their last six road night games.
• The Red Sox have trailed after 5 innings in eight of their last nine road games against American League opponents.

• Probable Starting Pitcher: Brayan Bello      Record this season: 1-2      ERA: 6.75
• Road Record: 1-1
• Last 5 against Orioles: 3-0

Why the Boston Red Sox will win

• The road team has won each of the last eight games between the Red Sox and Orioles.
• The Orioles have lost each of their last five games as home favorites against American League opponents following a win.
• The Orioles have failed to cover the run line in each of their last seven games as home favorites against American League opponents following a win.
• The underdogs have covered the run line in eight of the last nine games between the Red Sox and Orioles.
• The Red Sox have won the first inning in four of their last five games at Oriole Park at Camden Yards.
• The Orioles have trailed after 3 innings in each of their last five games against AL East opponents.
• The Orioles have trailed after 5 innings in four of their last five games.

Total Runs Facts

• Each of the Red Sox’s last seven games against AL East opponents have gone UNDER the total runs line.
• Seven of the last eight games between the Red Sox and Orioles have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last six road games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Orioles’ last 10 games as home favorites against AL East opponents.

Baltimore Orioles Player Prop Facts

• Gunnar Henderson has hit a home run in four of his last five appearances with the Orioles as home favorites against the Red Sox.
• Taylor Ward has recorded at least one hit in each of the Orioles’ last seven games as favorites against AL opponents.

Boston Red Sox Player Prop Facts

• Roman Anthony has hit a home run in three of his last four appearances in night games against teams that held a losing record.
• Roman Anthony has recorded at least one hit in each of his last 11 road appearances against opponents that held a losing record.

Matchup/League Facts

• The Orioles rank T25th in the league for strikeouts against this season (236).
• The Orioles rank 7th in the league for doubles this season (45).
• The Red Sox rank 30th in the league for slugging percentage this season (.331).
• The Red Sox rank T29th in the league for home runs this season (14).

Boston Red Sox vs. Baltimore Orioles Prediction

I’m on the Orioles here. I know the Red Sox just had a battle with the Yankees and that’s a big reason for their current struggles, but I’ve had issues backing this team pretty much all season long and all that series did was add fuel to my anti-Red Sox fire. The Orioles are a better team than what they’ve shown to this point, and I think this is a situation where the Orioles just take advantage of Boston while they’re down, so give me the Orioles in this one.

Chris Ruffolo's Pick: Baltimore -112