Baltimore Orioles vs Milwaukee Brewers Prediction 5/20/25 MLB Picks

In this article, we will formulate an Orioles vs Brewers prediction for this MLB game on Tuesday, May 20, at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Betting Preview

The Baltimore Orioles (15-31, 7-16 Away) have lost seven games in a row, their worst stretch of results this season. After a series win over the Los Angeles Angels, the Orioles were swept in back-to-back series by the Minnesota Twins and Washington Nationals. They opened this series in Milwaukee on Monday with a 5-4 defeat. Cedric Mullins led the offense with three RBI, while Dean Kremer pitched for 5.1 innings in a no-decision, allowing four runs on nine hits with six strikeouts and two walks. Yennier Cano took the loss.

This year, the Orioles average 3.76 runs per game (25th in the MLB) on a .230/.298/.388 triple-slash. When it comes to pitching, the Orioles’ staff has a 5.63 ERA (28th) and 1.48 WHIP (28th). Cedric Mullins leads the Orioles with a .229 batting average, ten home runs, and 30 RBI this season.

The projected starting pitcher for the Orioles is Keegan Akin, who is 0-0 in one start this season, with a 3.27 ERA and 1.23 WHIP in 22.0 innings.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (23-25, 14-9 Home) lost three consecutive series after suffering defeats to the Rays, Guardians, and Twins. The Brewers did manage to avoid a sweep with a Game 3 win over Minnesota, and then opened the current series against the Orioles with a 5-4 victory last night. Brice Turang and William Contreras led the team with two RBI apiece, while Quinn Priester pitched for 5.1 innings in a no-decision, allowing three runs on four hits with two strikeouts and one walk. Abner Uribe was credited with the win.

This season, the Brewers average 4.23 runs per game (16th in the MLB) on a .230/.308/.347 triple-slash. When it comes to pitching, the Brewers’ staff has a 4.14 ERA (19th) and 1.32 WHIP (20th). Christian Yelich leads the Brewers with a .194 batting average, seven home runs, and 26 RBI this season.

Logan Henderson will take the mound for the Brewers on Tuesday. The 23-year-old right-hander has a 2-0 record in two starts this year with a 2.45 ERA and 0.82 WHIP in 11.0 innings.

Why the Brewers will beat the Orioles

• The Orioles have lost each of their last eight night games against NL Central opponents that held a losing record.
• The Brewers have won eight of their last nine night games against American League opponents following a home win.
• The Orioles have failed to cover the run line each of their last 11 Tuesday night games against National League opponents that held a losing record.
• The favorites have covered the run line in three of the Brewers’ last four games.
• The Brewers have led after 5 innings in eight of their last nine games as home favorites against American League opponents.
• The Orioles have trailed after 3 innings in each of their last six night games against NL Central opponents.

Total Runs Facts

• Each of the last four games between the Orioles and Brewers have gone OVER the total runs line.
• Six of the Orioles’ last seven night games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Orioles’ last 10 night games against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Brewers’ last five home games against AL East opponents.

Matchup/League Facts

• The Brewers rank T27th in the league for home runs this season (37).
• The Brewers rank 26th in the league for walks allowed this season (178).
• The Orioles rank 29th in the league for opponent batting average this season (.277).
• The Orioles rank 27th in the league for walks this season (130).

Orioles vs Brewers Prediction

The Brewers won seven of the previous ten H2H encounters, including four of the last five. The Orioles will have a bullpen day in this one, and Keegan Akin will start on the mound, which is not a very encouraging sign for the struggling O’s. Akin hasn’t pitched from more than 2.0 innings in a game this year, and will likely stay that way on Tuesday, but I am sure the Brewers will get to him early on. Logan Henderson, on the other hand, impressed in his first two starts in the MLB. The rookie surrendered three runs in those two starts and registered 16 strikeouts with just two walks. I am backing him to record a quality start here and lead the Brewers to victory.