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Athletics vs Chicago White Sox Prediction 4/17/25 MLB Picks

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Chicago White Sox (4-13) vs Athletics (8-10)

April 17, 2025 at 02:10 PM EDT

The Line: Betting Odds: Chicago White Sox +136 / Athletics -162 — Over/Under: 8

(Get latest betting odds)

The Athletics and Chicago White Sox meet Thursday in MLB action at Rate Field. Here’s a Athletics vs Chicago White Sox Prediction. This article will include a Athletics vs Chicago White Sox Pick.

Athletics Betting Preview

The Athletics are 8-10 on the year and play the Brewers, Rangers, and White Sox next. The Athletics are batting .247 on the season, have a .312 OBP, and a .411 slugging percentage. The Athletics pitching staff has a 4.58 ERA and a 1.50 WHIP. Jacob Wilson leads the Athletics with 22 hits and 8 RBI, while Tyler Soderstrom and Lawrence Butler have combined for 41 hits and 21 RBI. 

JP Sears gets the ball for the Athletics, and he is 1-2 with a 4.24 ERA and 16 strikeouts this season. Sears is 1-3 with a 7.29 ERA and 19 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 4-13 on the year and play the Red Sox, Twins, and Athletics next. The Chicago White Sox are batting .200 on the season, have a .273 OBP, and a .306 slugging percentage. The Chicago White Sox pitching staff has a 4.03 ERA and a 1.30 WHIP. Lenyn Sosa leads the Chicago White Sox with 14 hits and 5 RBI while Brooks Baldwin and Miguel Vargas have combined for 21 hits and 14 RBI.

Davis Martin gets the ball for the Chicago White Sox, and he is 1-1 with a 4.24 ERA and 10 strikeouts this season. Martin is 0-0 with a 1.93 ERA and 7 strikeouts in his career against the Athletics.

Why the Chicago White Sox will win

  • The Athletics have lost five of their last six games as favorites following a win.
  • The White Sox have covered the run line in seven of their last eight day games against AL West opponents that held a losing record.
  • The Athletics have failed to cover the run line in six of their last seven day games against American League opponents.
  • The White Sox have led after 3 innings in each of their last five day games against the Athletics.
  • The White Sox have led after 5 innings in each of their last five day games against the Athletics.

Why the Athletics will win

  • The White Sox have lost 13 of their last 14 day games following a home loss.
  • The Athletics have won each of their last 10 Thursday games as road favorites.
  • The Athletics have covered the run line in each of their last five games against American League opponents.
  • The White Sox have failed to cover the run line in five of their last six games at Rate Field against teams that held a losing record.

Matchup/League Facts

  • The White Sox rank 29th in the league for runs scored this season (54).
  • The White Sox rank 29th in the league for RBIs this season (52).
  • The Athletics rank 27th in the league for ERA this season (4.58).
  • The Athletics rank 27th in the league for opponent batting average this season (.263).

Athletics vs Chicago White Sox Prediction

The Athletics aren’t world-beaters, but they’ve shown signs of life lately and are the better team here. The White Sox were historically bad last season and they’ve done nothing through 17 games to convince this season will be any different. The White Sox have scored three or fewer runs in 13 of their last 15 games. There’s going to be a lot of fading the White Sox this season and that includes this game. I want nothing to do with the White Sox in their current form. Give me the Athletics for the sweep, and I’ll lay the RL to shave down the juice.

Randy Chambers's Pick: Athletics -1.5

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