Astros vs Reds Prediction 5/10/2026 Today’s MLB Picks

In this article we will formulate an Astros vs Reds prediction for this MLB game on Sunday, May 10th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 16-24 this season after they split the first two games in this series by scores of 10-0 and 1-3. In game two, Houston led 1-0 in the fifth inning, but they couldn’t find anymore offense in the loss. The Astros recorded four hits and they committed two errors in the game, while they were led by Shewmake, who went 1-3 with one home run and one RBI. Arrighetti allowed five hits and one earned run over 5.2 innings for the loss, while Okert threw one scoreless inning in relief. Prior to this series, Houston lost two out of three against the Dodgers, but did win two out of three against the Red Sox before that. 

This season, Houston has a 5.56 ERA with a 1.59 WHIP and a .263 opponent batting average, while they have scored 196 runs with a .261 batting average and a .337 on base percentage. Yordan Alvarez has led the Astros with 13 home runs and 29 RBIs, while Christian Walker has added nine home runs and 27 RBIs. The projected starting pitcher for Houston is Kai-Wei Teng, who is 1-2 with a 2.35 ERA and a 0.96 WHIP over 23.0 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 21-19 this year after they won game two by a score of 3-1 on Saturday afternoon. Cincinnati scored all three of their runs in the fifth inning, which was enough to get the low scoring win. The Reds recorded five hits in the game and they were led by McLain, who went 1-3 with two RBIs. Burns allowed four hits and one earned run over 6.0 innings for the win, while Johnson picked up the save. Prior to this series, Cincinnati lost all four against the Cubs and all three against the Pirates. 

This season, Cincinnati has a 4.63 ERA with a 1.49 WHIP and a .254 opponent batting average, while they have scored 159 runs with a .218 batting average and a .303 on base percentage. Sal Stewart has led the Reds with 10 home runs and 30 RBIs, while Elly De La Cruz has added 10 home runs and 29 RBIs. The projected starting pitcher for Cincinnati is Andrew Abbott, who is 1-2 with a 5.13 ERA and a 1.64 WHIP over 40.1 innings pitched this year. 

Why the Cincinnati Reds will win

• The Reds have won seven of their last eight home games against the Astros.
• The Astros have lost each of their last five day games against National League opponents.
• The Astros have failed to cover the run line in seven of their last eight games against National League opponents after playing the previous day.
• The Reds have covered the run line in each of their last five home games against the Astros following a win.
• The Reds have led after 5 innings in six of their last eight games against the Astros at Great American Ball Park.

Why the Houston Astros will win

• The Astros have won each of their last four games as underdogs following a loss.
• The Reds have lost eight of their last nine games after playing the previous day.
• The underdogs have covered the run line in eight of the Astros’ last nine games at Great American Ball Park.
• The Reds have failed to cover the run line in seven of their last eight games at Great American Ball Park against AL West opponents that held a losing record.
• The Reds have trailed after 5 innings in 13 of their last 14 Sunday day games against AL West opponents that held a losing record.

Total Runs Facts

• Seven of the Reds’ last eight home games have gone OVER the total runs line.
• Four of the Astros’ last five games as underdogs against NL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Astros’ last eight road games against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Reds’ last five games as home favorites against American League opponents.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in four of the Reds’ last eight home games against AL opponents that held a losing record.
• Elly De La Cruz has recorded at least one hit in each of the Reds’ last eight games against AL West opponents.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in four of the Astros’ last five games against NL Central opponents that held a winning record.
• Jose Altuve has recorded at least one hit in each of his last eight appearances in day games against NL teams that held a winning record.

Astros vs Reds Prediction 

Cincinnati finally snapped their losing streak with a win on Saturday, but they have allowed 7+ runs in three of their last four games. The Reds are 11-9 at home this year, while the Astros are 7-14 on the road. Houston has alternated wins and losses over their last five games and they have scored three runs or fewer in four of their last five. The Astros are starting Teng, who will only pitch a couple of innings, while Abbott has allowed two earned runs in his last 11.2 innings. Take the Reds to get another win here.

David Racey's Pick: Reds ML