Arizona Diamondbacks base runner Alek Thomas (5) slides safely into third base against the San Francisco Giants at Chase Field on June 30, 2025.

Arizona Diamondbacks vs San Francisco Giants Prediction 07/03/2025 Picks

Pick details

San Francisco (46-41) vs Arizona (43-43)

July 3, 2025 at 09:40 PM EDT

The Line: Betting Odds: Arizona +100 / San Francisco -120 — Over/Under: +8.5

(Get latest betting odds)

The San Francisco Giants are visiting the Arizona Diamondbacks on Thursday, July 3rd at the Chase Field in the fourth game of this series, with the Dbacks having the 2-1 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs Arizona Diamondbacks Prediction. We will examine:
The Arizona Diamondbacks recent form and player performance
The San Francisco Giants recent form and player performance
Recent betting trends and streaks involving the Arizona Diamondbacks
Recent betting trends and streaks involving the San Francisco Giants
Recent betting trends in games played between the San Francisco Giants vs Arizona Diamondbacks
A summary that ties it all together and produces a favorable betting outcome for the San Francisco Giants vs Arizona Diamondbacks game

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 43-43 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 22-22 home record and are 44-37 in over/under They are coming off a 5-6 home defeat by the Giants, which ended their previous two-game winning streak. Over is 6-1 in their last 7 games and are playing the Padres and the Royals next.

The Diamondbacks have a .255 batting average this season, .329 OBP and .450 slugging percentage. Arizona’s pitching staff has a 4.71 ERA and 1.33 WHIP. Josh Naylor leads the Diamondbacks with 90 hits, and he is the team’s best hitter with a .303 batting average. Eugenio Suarez leads the team in RBI, with 69, and in home runs with 26.

Brandon Pfaadt (R) is the projected starting pitcher for the Diamondbacks, and he has an 8-5 record, 5.38 ERA and 1.38 WHIP.

San Francisco Giants Preview

The San Francisco Giants have a 46-41 record this season and are sitting on the third place of the NL West. They have a 21-24 road record and are 40-45 in over/under. They are coming off a 6-5 road victory over the Dbacks, which snapped their previous four-game losing streak. Under is 4-2 in their last 6 games, and are playing the Athletics and the Phillies next.

The Giants have a .230 batting average this season, .310 OBP and .371 Slugging percentage. San Francisco’s pitching staff has a 3.42 ERA and 1.25 WHIP.  Heliot Ramos leads the Giants with 89 hits and is the team’s best hitter, with a .275 batting average, adding a team-high 13 home runs. Wilmer Flores leads the team in RBI with 55.

Robbie Ray (R) is the projected starting pitcher for the Giants, and he has an 8-3 record, 2.75 ERA and 1.15 WHIP.

Why the Arizona Diamondbacks will win

The Giants have lost each of their last five games as favorites against National League opponents.
The Diamondbacks have won each of their last four games as underdogs against National League opponents.
The Diamondbacks have covered the run line in each of their last nine Thursday games as underdogs against National League opponents.
The Giants have failed to cover the run line in 10 of their last 11 games as favorites against National League opponents.
The Diamondbacks have led after 5 innings in each of their last seven Thursday games against National League opponents that held a winning record.
The Giants have trailed after 3 innings in three of their last four games as favorites against National League opponents.

Why the San Francisco Giants will win

The Giants have won each of their last seven games following an extra innings win.
The Diamondbacks have lost four of their last five night games after going to extra innings.
The Diamondbacks have failed to cover the run line in each of their last six night games at Chase Field following an extra innings loss.
The Giants have covered the run line in each of their last four road games after going to extra innings.
The Diamondbacks have trailed after 3 innings in four of their last five night games against opponents that held a winning record.

Total Runs Facts

Fourteen of the Diamondbacks’ last 15 games following an extra innings loss have gone OVER the total runs line.
Each of the Giants’ last four games as favorites have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Giants’ last 15 night games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the last five games between the Giants and Diamondbacks at Chase Field.

Matchup/League Facts

The Diamondbacks rank T2nd in the league for doubles this season (151).
The Diamondbacks rank 2nd in the league for slugging percentage this season (.450).
The Giants rank 2nd in the league for ERA this season (3.42).
The Giants rank T2nd in the league for home runs allowed this season (73).

San Francisco Giants vs Arizona Diamondbacks Prediction

The Dbacks are 5-1 in their last 6 meetings against the Giants, and both teams are tied 3-3 in their last 6 meetings in Arizona. Over is 8-3-1 in their last 12 meetings.  
In this San Francisco Giants vs Arizona Diamondbacks Prediction, the Giants are coming as -120 road favorites. The Giants have a slightly better overall record, but both teams have almost identical home/away splits. The Giants have the best bullpen in the league, and they have the pitching advantage today, as Robbie Ray with a 2.75 ERA, is facing Brandon Pfaadt who has been abysmal lately, with a 11.00 ERA in his last five starts. Pfaadt also had 4 earned runs in 4 innings pitched in his last previous start against the Giants this season, so I expect the guests to take care of business in this one. Take the San Francisco Giants on the moneyline.

Nikos Lagouretos's Pick: San Francisco Giants -120

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