Arizona Diamondbacks infielder Geraldo Perdomo (2) tags out San Francisco Giants base runner Dominic Smith (7) at Chase Field on June 30, 2025.

Arizona Diamondbacks vs San Francisco Giants Prediction 07/01/2025 Picks

Pick details

San Francisco (45-40) vs Arizona (42-42)

July 1, 2025 at 09:40 PM EDT

The Line: Betting Odds: Arizona -135 / San Francisco +115 — Over/Under: +9

(Get latest betting odds)

The San Francisco Giants are visiting the Arizona Diamondbacks on Tuesday, July 1st at the Chase Field in the second game of this series, with the Dbacks having the 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs Arizona Diamondbacks Prediction. We will examine:
The Arizona Diamondbacks recent form and player performance
The San Francisco Giants recent form and player performance
Recent betting trends and streaks involving the Arizona Diamondbacks
Recent betting trends and streaks involving the San Francisco Giants
Recent betting trends in games played between the San Francisco Giants vs Arizona Diamondbacks
A summary that ties it all together and produces a favorable betting outcome for the San Francisco Giants vs Arizona Diamondbacks game

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 42-42 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 21-21 home record and are 42-37 in over/under They are coming off a 4-2 home victory over the Giants, which snapped their previous four-game losing streak. Over is 4-1 in their last 5 games and are playing the Padres and the Royals next.

The Diamondbacks have a .254 batting average this season, .329 OBP and .447 slugging percentage. Arizona’s pitching staff has a 4.75 ERA and 1.34 WHIP. Josh Naylor leads the Diamondbacks with 89 hits, and he is the team’s best hitter with a .304 batting average. Eugenio Suarez leads the team in RBI, with 69, and in home runs with 26.

Zac Gallen (R) is the projected starting pitcher for the Diamondbacks, and he has a 5-9 record, 5.75 ERA and 1.41 WHIP.

San Francisco Giants Preview

The San Francisco Giants have a 45-40 record this season and are sitting on the third place of the NL West. They have a 20-23 road record and are 38-45 in over/under. They are coming off a 2-4 road defeat by the Dbacks, and are 1-6 in their last 7 games. Under is 4-0 in their last 4 games, and are playing the Athletics and the Phillies next.

The Giants have a .230 batting average this season, .311 OBP and .371 Slugging percentage. San Francisco’s pitching staff has a 3.39 ERA and 1.24 WHIP.  Heliot Ramos leads the Giants with 88 hits and is the team’s best hitter, with a .275 batting average, adding a team-high 13 home runs. Wilmer Flores leads the team in RBI with 55.

Hayden Birdsong (R) is the projected starting pitcher for the Giants, and he has a 3-2 record, 4.13 ERA and 1.38 WHIP.

Why the Arizona Diamondbacks will win

The Diamondbacks have won each of their last seven night games following a win.
The Giants have lost each of their last six games against National League opponents.
The Diamondbacks have covered the run line in each of their last seven night games following a win.
The Giants have failed to cover the run line in eight of their last nine games following a loss.
The Giants have lost the first inning in five of their last six games as underdogs against NL West opponents.
The Diamondbacks have led after 5 innings in eight of their last nine night games against NL West opponents.
The Diamondbacks have led after 3 innings in each of their last five home night games.

Why the San Francisco Giants will win

The underdogs have won each of the Diamondbacks’ last five games.
The Diamondbacks have lost each of their last four games as favorites.
The Giants have covered the run line in each of their last nine games as underdogs following a loss.
The Diamondbacks have failed to cover the run line in 14 of their last 16 home games against National League opponents following a home win.
The Diamondbacks have lost the first inning in three of their last four night games against opponents that held a winning record.

Total Runs Facts

Each of the Diamondbacks’ last five games as home favorites have gone OVER the total runs line.
Thirteen of the Giants’ last 15 night games as underdogs have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last six games as underdogs against NL West opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Diamondbacks’ last six games as favorites.

Matchup/League Facts

The Diamondbacks rank 2nd in the league for doubles this season (149).
The Diamondbacks rank 2nd in the league for slugging percentage this season (.447).
The Giants rank 2nd in the league for ERA this season (3.39).
The Giants rank 2nd in the league for home runs allowed this season (67).

San Francisco Giants vs Arizona Diamondbacks Prediction

The Dbacks are 4-1 in their last 5 meetings against the Giants, but the Giants are 3-2 in their last 5 visits in Arizona. Over is 7-3-1 in their last 11 meetings.   
In this San Francisco Giants vs Arizona Diamondbacks Prediction, the Diamondbacks are coming as -135 home favorites. The Giants have a better overall record, but both teams have almost identical home/away splits. Gallen has been terrible for the Dbacks this season, but the Giants have been in terrible form lately, and their offense is struggling. The Dbacks have a better offense, and are better against right-handed pitching. If the Giants cannot win with Logan Webb on the mound, they will surely not win with Birdsong. Take the Dbacks to take care of business at home.

Nikos Lagouretos's Pick: Arizona Diamondbacks -135

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