Sep 13, 2025; Minneapolis, Minnesota, USA; Arizona Diamondbacks catcher Gabriel Moreno (14) dislikes the called third strike against him and for the Minnesota Twins in the eighth inning at Target Field. Mandatory Credit: Bruce Kluckhohn-Imagn Images

Arizona Diamondbacks vs Minnesota Twins Prediction 9/14/2025 Today’s MLB Picks

Pick details

Arizona (74-75) vs Minnesota (65-83)

September 14, 2025 at 02:10 PM EDT

The Line: Betting Odds: Minnesota -125 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a Diamondbacks vs Twins Prediction for this MLB game on Sunday, September 14th at the Target Field the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Minnesota Twins Preview

The Minnesota Twins have a 65-83 record this season and are sitting on the 4th place of the AL Central. The Twins have a 36-37 home record and are 70-69 in over/under. They are coming off a 2-5 home defeat by the Dbacks, and are 1-3 in their last 4 games. Over is 7-5 in their last 12 games and are playing the Yankees and the Guardians next.

The Twins have a .240 batting average this season, .313 OBP and .399 Slugging percentage. Minnesota’s pitching staff has a 4.60 ERA and 1.33 WHIP. Trevor Larnach leads the Twins with 119 hits, while Byron Buxton adds team-highs both in RBI, with 76, and in home runs, with 31. He is also the team’s best hitter with a .274 batting average.

Bailey Ober (R) is the projected starter for the Twins, and he has a 5-7 record, 5.08 ERA and 1.34 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 74-75 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 35-41 road record and are 71-69 in over/under They are coming off a 5-2 road victory over the Twins, that ended their three-game losing streak. Over is 4-2 in their last 6 games and are playing the Phillies and the Giants next.

The Diamondbacks have a .250 batting average this season, .323 OBP and .434 slugging percentage. Arizona’s pitching staff has a 4.49 ERA and 1.32 WHIP. Geraldo Perdomo leads the Diamondbacks with 156 hits, adding a team-high 95 RBI. He Is also the team’s best hitter with a .286 batting average, while Corbin Carroll leads the team in home runs with 29.

Nabil Crismatt (R) is the projected starting pitcher for the Diamondbacks, and he has a 2-0 record, 3.24 ERA and 1.40 WHIP.

Arizona Diamondbacks @ Minnesota Twins Betting Trends: September 14, 2025


  • Probable Starting Pitcher: Bailey Ober      Record this season: 5-7      ERA: 5.08
  • Home Record: 2-4
  • Last 5 against Diamondbacks: 0-0

Why the Minnesota Twins will win

  • The Twins have won each of their last eight day games against NL West opponents following a loss.
  • The Diamondbacks have lost nine of their last 10 games at Target Field.
  • The Twins have covered the run line in each of their last eight day games against NL West opponents following a loss.
  • The Diamondbacks have failed to cover the run line in four of their last five road games after going to extra innings.
  • The Diamondbacks have trailed after 5 innings in five of their last six road games against AL Central opponents.

  • Probable Starting Pitcher: Nabil Crismatt      Record this season: 2-0      ERA: 3.24
  • Road Record: 1-0
  • Last 5 against Twins: 0-0

Why the Arizona Diamondbacks will win

  • The Twins have lost each of their last seven games as favorites after playing the previous day.
  • The Diamondbacks have won each of their last six Sunday games as underdogs against American League opponents.
  • The underdogs have covered the run line in each of the Twins’ last 12 games.
  • The Twins have failed to cover the run line each of their last nine home games against teams that held a losing record.
  • The Twins have trailed after 5 innings in each of their last four day games against opponents that held a losing record.
  • The Twins have lost the first inning in three of their last four games as favorites.
  • The Twins have trailed after 3 innings in each of their last four day games against opponents that held a losing record.

Total Runs Facts

  • Five of the Diamondbacks’ last six games as underdogs against the Twins have gone OVER the total runs line.
  • Five of the Twins’ last six home games against NL West opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last four day games at Target Field.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Diamondbacks’ last seven day games.

Minnesota Twins Player Prop Facts

  • Trevor Larnach has recorded a Double in four of his last five appearances in day games.
  • Bailey Ober has recorded five or more strikeouts in each of his last four appearances against NL opponents that held a losing record.
  • Ryan Jeffers has hit at least one home run in three of his last four appearances with the Twins as favorites against the Diamondbacks.
  • Ryan Jeffers has recorded at least one hit in each of his last six appearances with the Twins as favorites against NL opponents.
  • Byron Buxton ranks 5th amongst qualified players for Slugging Percentage (.561) this season.

Arizona Diamondbacks Player Prop Facts

  • Lourdes Gurriel Jr. has hit a home run in each of his two previous appearances with the Diamondbacks as road underdogs against the Twins.
  • Lourdes Gurriel Jr. has recorded at least one hit in each of his last eight road appearances against the Twins.
  • Corbin Carroll ranks 6th amongst qualified players for Slugging Percentage (.544) this season.

Matchup/League Facts

  • The Twins rank 3rd in the league for walks allowed this season (424).
  • The Twins rank 27th in the league for opponent batting average this season (.260).
  • The Diamondbacks rank T1st in the league for triples this season (35).
  • The Diamondbacks rank 3rd in the league for RBIs this season (717).

Diamondbacks vs Twins Prediction

The Twins are 6-2 in their last 8 head-to-head meetings against the Diamondbacks, and are 5-1 in their last 6 meetings in Minnesota. Over is 5-2 in their last 7 meetings.

In this Diamondbacks vs Twins Prediction, the Twins are coming as -125 home favorites. I don’t trust Ober on the mound for the Twins, and Crismatt has been weaker on the road for the Dbacks, with a 4.30 road ERA. Both teams are better against right-handed pitching, averaging 9.6 runs per game against righties, and both teams have bottom-5 bullpen
ERA. I expect a lot of runs in this game, so take the over 9 runs.

Nikos Lagouretos's Pick: Over 9

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