Feb 21, 2026; Tempe, Arizona, USA; Los Angeles Dodgers pitcher Yoshinobu Yamamoto against the Los Angeles Angels during a spring training game at Tempe Diablo Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images
Mark J. Rebilas-Imagn Images

Arizona Diamondbacks vs. Los Angeles Dodgers Prediction 3/26/25 MLB Picks

Pick details

MATCHUP Arizona Diamondbacks Los Angeles Dodgers
Team Records 0-0 0-0
Spread +1.5 104 -1.5 -126
Moneyline +209 -259
Total Over 9 (-102) Under 9 (-118)
Where Dodger Stadium, Los Angeles, California
When Thursday, March 26, 2026
Time 08:30 PM EDT
TV NBC

The Arizona Diamondbacks and the Los Angeles Dodgers will meet on Thursday night at Dodger Stadium in Los Angeles, California.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks finished the 2025 season with an 81–81 win-loss record, placing third in the National League West. Arizona did not qualify for the postseason and enters 2026 looking to rebound behind its established core and frontline pitching. The Diamondbacks will open the season on the road, where they were competitive at times last year but struggled with consistency.

The confirmed Opening Day starter for Arizona is Zac Gallen, who remains the anchor of the rotation. Gallen is coming off another strong season and continues to be one of the most reliable starters in the National League. Last season, Zac Gallen compiled a 13-15 win-loss record, a 4.83 ERA, 175 strikeouts (25th in MLB) and a 1.26 WHIP. His presence on the mound gives the Diamondbacks a legitimate chance to control this matchup.

Arizona’s lineup returns several key contributors, including Corbin Carroll and Ketel Marte, both of whom remain central to the team’s offensive identity. Let’s take a look at the numbers to better illustrate Carroll and Marte’s contributions last season. Outfielder Corbin Carroll amassed 31 home runs (21st in MLB), 84 RBIs and an .883 OPS which ranked ninth in Major League Baseball, while second baseman Ketel Marte compiled a .283 batting average (22nd in MLB), 72 RBIs and an .893 OPS.       

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers finished the 2025 season with a 93–69 record, winning the National League West and continuing their run as one of baseball’s most successful franchises. Los Angeles also posted a 7–6 record against the Diamondbacks last season, giving them a slight edge in the head‑to‑head matchup entering Opening Day.

The Dodgers will start Yoshinobu Yamamoto, who delivered an outstanding first MLB season in 2025. Yamamoto finished the year with a 12–8 win-loss record, a 2.49 ERA (4th in MLB) , 201 strikeouts and a 0.99 WHIP which ranked sixth in Major League Baseball. His elite command and strikeout ability give Los Angeles a clear advantage in this game.

Los Angeles returns a deep and experienced lineup featuring Mookie Betts, Freddie Freeman, and Will Smith, all of whom remain central to the Dodgers offensive production. Let me be more specific. In 2025, first baseman Freddie Freeman compiled a rather impressive .295 batting average (9th in MLB), 24 home runs, 90 RBIs and an .869 OPS. Catcher Will Smith amassed a .296 batting average and an .901 OPS, while shortstop Mookie Betts compiled a .258 batting average, 20 home runs and 82 RBIs.     

Why the Arizona Diamondbacks will win.

• Zac Gallen gives Arizona a legitimate chance to control the early innings in this matchup.

• The Diamondbacks were competitive in the season series last year. More specifically, in 13 games played in 2025, the Diamondbacks compiled a 6-7 record versus the Dodgers.

• Arizona’s speed and athleticism can pressure opposing defenses.

• The Diamondbacks core lineup remains intact entering the 2026 MLB regular season.

Why the Los Angeles Dodgers will win.

• Los Angeles finished 93–69 last season and won the NL West.

• Yamamoto is coming off a top‑three Cy Young finish with elite strikeout numbers.

• The Dodgers lineup remains one of the deepest in baseball.

• Los Angeles has historically performed well in Opening Day home games.

Arizona Diamondbacks vs. Los Angeles Dodgers Prediction

This matchup features Arizona’s best starting pitcher in Zac Gallen, but the Dodgers enter tomorrow’s contest with the deeper roster, the stronger offensive core, and a clear mound advantage behind Yoshinobu Yamamoto. Yamamoto’s command and strikeout profile pair with an offense that can perform at a high level. With that said, Los Angeles is the right side to be on in this matchup. For the reasons just noted, I am backing the Dodgers to cover the 1.5 runs in this game.

Hans Geevers's Pick: Los Angeles Dodgers -1.5