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St. Louis Cardinals vs Milwaukee Brewers Prediction 6/14/25 MLB Picks

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Milwaukee Brewers (38-33) vs St. Louis Cardinals (36-34)

June 14, 2025 at 04:10 PM EDT

The Line: Betting Odds: Milwaukee Brewers -123 / St. Louis Cardinals +101 — Over/Under: 8

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In this article, we will formulate a Cardinals vs Brewers prediction for this MLB game on Saturday, June 14, at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals (36-34, 14-20 Away) are going through their worst period of the season after suffering six consecutive defeats. St. Louis lost to the Dodgers (but won that series), was swept by the Blue Jays, and lost the opening two games of the current series against the Brewers. In Friday’s 3-2 defeat, Erick Fedde took the loss after allowing three runs on four hits with five strikeouts and one walk in 5.1 innings. 

This year, the Cardinals average 4.54 runs per game (9th in the MLB) on a .255/.326/.390 triple-slash. When it comes to pitching, the Cardinals’ staff has a 4.00 ERA (18th) and 1.28 WHIP (16th). Willson Contreras leads the Cardinals with a .255 batting average, eight home runs, and 43 RBI this season.

The projected starting pitcher for the Cardinals is Andre Pallante, who is 4-3 in 13 starts this season, with a 4.75 ERA and 1.38 WHIP in 72.0 innings.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (38-33, 22-14 Home) lost back-to-back series at home to the San Diego Padres and Atlanta Braves, but will surely avoid the third straight defeat after beating the Cardinals in the first two games of the current series. Following a 6-0 win, the Brewers edged out the Cards 3-2. William Contreras led the team with two RBI, while Freddy Peralta got the win after allowing one run on four hits with six strikeouts and one walk across 6.0 innings of work.

This season, the Brewers’ average 4.34 runs per game (13th in the MLB) on a .235/.312/.362 triple-slash. When it comes to pitching, the Brewers’ staff has a 3.78 ERA (13th) and 1.30 WHIP (18th). Christian Yelich leads the Brewers with a .236 batting average, 13 home runs, and 42 RBI this season.

Jose Quintana will take the mound for the Brewers on Saturday. The 36-year-old left-hander has a 4-1 record in eight starts this year with a 2.66 ERA and 1.32 WHIP in 44.0 innings.

Why the Brewers will beat the Cardinals

  • The Cardinals have lost each of their last six games after playing the previous day.
  • The home team has won four of the last five games between the Cardinals and Brewers.
  • The Brewers have covered the run line in seven of their last eight day games against NL Central opponents that held a winning record.
  • The Cardinals have failed to cover the run line in five of their last six games against teams that held a winning record.
  • The Brewers have led after 5 innings in 14 of their last 18 day games against the Cardinals.

Total Runs Facts

  • Each of the Brewers’ last four games as favorites have gone UNDER the total runs line.
  • Six of the Cardinals’ last seven road games against National League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last 10 games at American Family Field.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last five games against National League opponents.

Matchup/League Facts

  • The Brewers rank 28th in the league for walks allowed this season (255).
  • The Brewers rank 25th in the league for doubles this season (94).
  • The Cardinals rank 3rd in the league for home runs allowed this season (57).
  • The Cardinals rank 4th in the league for doubles this season (124).

Cardinals vs Brewers Prediction

The Cardinals won six of the previous ten H2H encounters, but the Brewers lead this season’s series 3-2. Milwaukee won three straight, and I am backing the hosts to win again on Saturday. Jose Quintana already faced the Cards this season and secured a win after allowing just one run in 5.0 innings. Quintana surrendered four runs in his previous three starts, and I am backing him to display another strong start here. Andre Pallante, on the other hand, allowed multiple runs in ten consecutive starts, and I believe Milwaukee will score 3+ off him in the opening five innings. Back the Brewers. 

Oliver Zivic's Pick: Brewers ML

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